DK338985A - 1-(substitueret alkyl)-3-(3-hydroxyphenyl)piperidin-forbindelser ogfremgangsmaade til fremstilling deraf samt farmaceutiske praeparaterindeholdende disse - Google Patents

1-(substitueret alkyl)-3-(3-hydroxyphenyl)piperidin-forbindelser ogfremgangsmaade til fremstilling deraf samt farmaceutiske praeparaterindeholdende disse Download PDF

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Publication number
DK338985A
DK338985A DK338985A DK338985A DK338985A DK 338985 A DK338985 A DK 338985A DK 338985 A DK338985 A DK 338985A DK 338985 A DK338985 A DK 338985A DK 338985 A DK338985 A DK 338985A
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Prior art keywords
piperidine compounds
useful
formula
hydroxyphenyl
procedures
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Application number
DK338985A
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English (en)
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DK167974B1 (da
DK338985D0 (da
Inventor
Reinhard Sarges
Original Assignee
Pfizer
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Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK338985D0 publication Critical patent/DK338985D0/da
Publication of DK338985A publication Critical patent/DK338985A/da
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Publication of DK167974B1 publication Critical patent/DK167974B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK338985A 1984-07-26 1985-07-25 1-(phenylalkyl)-3-(3-hydroxyphenyl)piperidin-forbindelser fremgangsmaade til fremstilling deraf og 3-(3-methoxyphenylpiperidin-forbindelser til anvendelse som mellemprodukter ved deres fremstilling samt farmaceutiske praeparater indeholdende de foerstnaevnte forbindelser DK167974B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/634,910 US4593037A (en) 1984-07-26 1984-07-26 1,3-disubstituted piperidine compounds as neuroleptic agents
US63491084 1984-07-26

Publications (3)

Publication Number Publication Date
DK338985D0 DK338985D0 (da) 1985-07-25
DK338985A true DK338985A (da) 1986-03-13
DK167974B1 DK167974B1 (da) 1994-01-10

Family

ID=24545655

Family Applications (1)

Application Number Title Priority Date Filing Date
DK338985A DK167974B1 (da) 1984-07-26 1985-07-25 1-(phenylalkyl)-3-(3-hydroxyphenyl)piperidin-forbindelser fremgangsmaade til fremstilling deraf og 3-(3-methoxyphenylpiperidin-forbindelser til anvendelse som mellemprodukter ved deres fremstilling samt farmaceutiske praeparater indeholdende de foerstnaevnte forbindelser

Country Status (8)

Country Link
US (1) US4593037A (da)
EP (1) EP0175452B1 (da)
JP (1) JPS6137768A (da)
AT (1) ATE37358T1 (da)
DE (1) DE3565102D1 (da)
DK (1) DK167974B1 (da)
GR (1) GR851811B (da)
IE (1) IE58121B1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0299549A3 (en) * 1987-07-09 1989-02-08 Duphar International Research B.V Tertiary 2,5-dialkyl-3-phenyl-piperidine derivatives having opiate-antagonistic activity
HU207310B (en) * 1988-12-02 1993-03-29 Pfizer Process for producing aryl-piperidine derivatives
US5109002A (en) * 1989-09-08 1992-04-28 Du Pont Merck Pharmaceutical Company Antipsychotic 1-cycloalkylpiperidines
US5459151A (en) * 1993-04-30 1995-10-17 American Home Products Corporation N-acyl substituted phenyl piperidines as bronchodilators and antiinflammatory agents
US5457207A (en) * 1993-10-05 1995-10-10 Regents Of The University Of Minnesota Spirovesamicols
DE102004036349A1 (de) * 2004-07-27 2006-03-23 Grünenthal GmbH Substituierte 3-Phenylpiperidin-Derivate
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB984119A (en) * 1960-06-20 1965-02-24 Aspro Nicholas Ltd Substituted piperidines and methods for their preparation
GB1044309A (en) * 1964-05-07 1966-09-28 Koninklijke Pharma Fab Nv Substituted 1-aralklyl-piperidines
FR2310762A1 (fr) * 1975-05-16 1976-12-10 Roussel Uclaf Nouveaux derives n-substitues de la phenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments
US4241071A (en) * 1977-01-27 1980-12-23 American Hoechst Corporation Antidepressant (α-phenyl-2-tolyl)azacycloalkanes
US4332942A (en) * 1977-09-13 1982-06-01 Pfizer, Inc. 3-(2-Hydroxy-4-(substituted)phenyl)azacycloalkanes as analgesics
CA1147339A (en) * 1979-12-05 1983-05-31 Folke L. Arvidsson Phenyl-azacykloalkanes

Also Published As

Publication number Publication date
ATE37358T1 (de) 1988-10-15
US4593037A (en) 1986-06-03
IE58121B1 (en) 1993-07-14
JPH0533696B2 (da) 1993-05-20
IE851857L (en) 1986-01-26
GR851811B (da) 1985-11-26
JPS6137768A (ja) 1986-02-22
EP0175452B1 (en) 1988-09-21
DE3565102D1 (en) 1988-10-27
DK167974B1 (da) 1994-01-10
EP0175452A1 (en) 1986-03-26
DK338985D0 (da) 1985-07-25

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed