DK3389697T3 - Selektive glucagon-receptor-agonister omfattende en chelaterende del til billeddannelsesformål - Google Patents

Selektive glucagon-receptor-agonister omfattende en chelaterende del til billeddannelsesformål Download PDF

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Publication number
DK3389697T3
DK3389697T3 DK16819291.2T DK16819291T DK3389697T3 DK 3389697 T3 DK3389697 T3 DK 3389697T3 DK 16819291 T DK16819291 T DK 16819291T DK 3389697 T3 DK3389697 T3 DK 3389697T3
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Prior art keywords
receptor agonists
glucagon receptor
chelating moiety
imaging purposes
selective glucagon
Prior art date
Application number
DK16819291.2T
Other languages
English (en)
Inventor
Torsten Haack
Oliver Plettenburg
Andreas Evers
Michael Wagner
Martin Bossart
Romain Bertrand
Original Assignee
Antaros Medical Ab
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Publication of DK3389697T3 publication Critical patent/DK3389697T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK16819291.2T 2015-12-14 2016-12-12 Selektive glucagon-receptor-agonister omfattende en chelaterende del til billeddannelsesformål DK3389697T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15307000 2015-12-14
PCT/EP2016/080553 WO2017102613A1 (en) 2015-12-14 2016-12-12 Selective glucagon receptor agonists comprising a chelating moiety for imaging purposes

Publications (1)

Publication Number Publication Date
DK3389697T3 true DK3389697T3 (da) 2021-01-11

Family

ID=55129466

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16819291.2T DK3389697T3 (da) 2015-12-14 2016-12-12 Selektive glucagon-receptor-agonister omfattende en chelaterende del til billeddannelsesformål

Country Status (21)

Country Link
US (1) US11046743B2 (da)
EP (1) EP3389697B1 (da)
JP (1) JP6986516B2 (da)
KR (1) KR20180086270A (da)
CN (1) CN108697767B (da)
AU (1) AU2016372245B2 (da)
BR (1) BR112018011892A2 (da)
CA (1) CA3008052C (da)
DK (1) DK3389697T3 (da)
ES (1) ES2846023T3 (da)
HR (1) HRP20210073T1 (da)
HU (1) HUE053079T2 (da)
IL (1) IL259961A (da)
LT (1) LT3389697T (da)
MX (1) MX2018007323A (da)
PL (1) PL3389697T3 (da)
PT (1) PT3389697T (da)
RU (1) RU2018125958A (da)
SG (1) SG11201804993RA (da)
SI (1) SI3389697T1 (da)
WO (1) WO2017102613A1 (da)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004043153B4 (de) 2004-09-03 2013-11-21 Philipps-Universität Marburg Erfindung betreffend GLP-1 und Exendin
AU2006249869A1 (en) * 2005-05-26 2006-11-30 Bristol-Myers Squibb Company N-terminally modified GLP-1 receptor modulators
US20100022457A1 (en) * 2006-05-26 2010-01-28 Bristol-Myers Squibb Company Sustained release glp-1 receptor modulators
UA116217C2 (uk) * 2012-10-09 2018-02-26 Санофі Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
CN104902920A (zh) * 2012-12-21 2015-09-09 赛诺菲 作为glp1/gip双重激动剂或glp1/gip/胰高血糖素三重激动剂的毒蜥外泌肽-4衍生物
US9932381B2 (en) * 2014-06-18 2018-04-03 Sanofi Exendin-4 derivatives as selective glucagon receptor agonists

Also Published As

Publication number Publication date
ES2846023T3 (es) 2021-07-28
BR112018011892A2 (pt) 2018-12-04
KR20180086270A (ko) 2018-07-30
EP3389697B1 (en) 2020-12-16
RU2018125958A3 (da) 2020-06-09
SG11201804993RA (en) 2018-07-30
CA3008052A1 (en) 2017-06-22
CN108697767A (zh) 2018-10-23
LT3389697T (lt) 2021-02-10
IL259961A (en) 2018-07-31
AU2016372245B2 (en) 2020-07-16
US11046743B2 (en) 2021-06-29
PL3389697T3 (pl) 2021-04-19
HUE053079T2 (hu) 2021-06-28
PT3389697T (pt) 2021-01-22
WO2017102613A1 (en) 2017-06-22
CA3008052C (en) 2024-01-02
CN108697767B (zh) 2022-04-15
HRP20210073T1 (hr) 2021-04-30
MX2018007323A (es) 2019-01-10
RU2018125958A (ru) 2020-01-20
EP3389697A1 (en) 2018-10-24
JP6986516B2 (ja) 2021-12-22
US20200262885A1 (en) 2020-08-20
SI3389697T1 (sl) 2021-02-26
AU2016372245A1 (en) 2018-07-26
JP2019508480A (ja) 2019-03-28

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