DK3365323T3 - Salte af tetracycliner - Google Patents

Salte af tetracycliner Download PDF

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Publication number
DK3365323T3
DK3365323T3 DK16805888.1T DK16805888T DK3365323T3 DK 3365323 T3 DK3365323 T3 DK 3365323T3 DK 16805888 T DK16805888 T DK 16805888T DK 3365323 T3 DK3365323 T3 DK 3365323T3
Authority
DK
Denmark
Prior art keywords
tetracyclines
salts
Prior art date
Application number
DK16805888.1T
Other languages
English (en)
Inventor
De Arruda Livia Santana
Rafael Antunes
Margarida Figueiredo
Ana Paula Filipe
Luis Sobral
Original Assignee
Hovione Scientia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hovione Scientia Ltd filed Critical Hovione Scientia Ltd
Application granted granted Critical
Publication of DK3365323T3 publication Critical patent/DK3365323T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
DK16805888.1T 2015-11-24 2016-11-24 Salte af tetracycliner DK3365323T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT108978A PT108978B (pt) 2015-11-24 2015-11-24 Sais de tetraciclinas
PCT/GB2016/053695 WO2017089809A1 (en) 2015-11-24 2016-11-24 Salts of tetracyclines

Publications (1)

Publication Number Publication Date
DK3365323T3 true DK3365323T3 (da) 2020-04-06

Family

ID=57482470

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16805888.1T DK3365323T3 (da) 2015-11-24 2016-11-24 Salte af tetracycliner

Country Status (14)

Country Link
US (1) US10543298B2 (da)
EP (1) EP3365323B1 (da)
JP (1) JP6883578B2 (da)
CN (1) CN108602761B (da)
AU (1) AU2016358448B2 (da)
CA (1) CA3005806A1 (da)
CY (1) CY1122679T1 (da)
DK (1) DK3365323T3 (da)
ES (1) ES2775702T3 (da)
HU (1) HUE048839T2 (da)
IL (1) IL259572B (da)
PL (1) PL3365323T3 (da)
PT (1) PT108978B (da)
WO (1) WO2017089809A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CN102686205A (zh) 2009-10-02 2012-09-19 弗艾米克斯有限公司 局部四环素组合物
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas
MX2017011630A (es) 2016-09-08 2018-09-25 Foamix Pharmaceuticals Ltd Composiciones y metodos para tratar rosacea y acne.
CN115380022A (zh) * 2018-04-06 2022-11-22 帕拉特克药品公司 萨瑞环素盐酸盐的制造方法
CN110156624B (zh) * 2019-05-29 2022-03-08 河北冀衡药业股份有限公司 一种米诺环素及其衍生物的合成方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR892088A (fr) * 1942-03-10 1944-03-28 Forsch U Verwertungsgesellscha Procédé pour obtenir du caoutchouc à partir de parties de plantes qui en contiennent
CH365484A (fr) 1956-05-28 1962-11-15 American Cyanamid Co Procédé de préparation d'une substance antibiotique
US2929837A (en) * 1957-01-30 1960-03-22 American Cyanamid Co Method of purifying tetracycline
DE1045398B (de) * 1957-05-03 1958-12-04 Hiroshi Ogawa Verfahren zur Herstellung von reinen Tetracyclinsalzen bzw. reinem Tetracyclin
GB901209A (en) 1957-10-23 1962-07-18 Pfizer & Co C 6-deoxytetracyclines and compositions containing same
US2886595A (en) 1958-09-30 1959-05-12 Bristol Lab Inc Tetracycline recovery
US3036120A (en) * 1958-11-10 1962-05-22 Pfizer & Co C Dicarboxylic acid derivatives of tetracycline and its analogs
US3019260A (en) 1959-05-13 1962-01-30 American Cyanamid Co Process for the catalytic reduction of 6-hydroxy hydronaphthacenes
FR1430859A (da) 1960-05-23 1966-05-25
BE615425A (fr) * 1961-03-24 1962-07-16 Erba Carlo Spa Nouveaux sels de dérivés des antibiotiques du type tétracycline
US3042716A (en) 1961-12-04 1962-07-03 Pfizer & Co C Mannich bases of tetracycline compounds and amino acids
USRE26253E (en) 1963-05-17 1967-08-15 And z-alkylamino-g-deoxytetracycline
FR1453301A (fr) * 1965-05-17 1966-06-03 Manufactures J R Bottu Nouveau dérivé de la tétracycline et procédé de préparation
FR92088E (fr) 1966-10-25 1968-09-20 American Cyanamid Co Procédé de préparation des aminotétracyclines substituées
DE1767891C3 (de) 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
BE792050A (fr) * 1971-12-04 1973-03-16 Amezua Fernandez Piedal Procede d'obtention d'un nouveau derive antibiotique
US4743699A (en) 1982-01-19 1988-05-10 Plurichemie Anstalt Homogeneous catalytic system and a process for the preparation of same
BE896423A (fr) 1983-04-11 1983-08-01 Ct Europ De Rech S Therapeutiq Nouveaux sels liposolubles de doxycycline et leur preparation
PT102160B (pt) 1998-05-26 2001-04-30 Hovione Sociedade Quimica S A Processo para a preparacao de 4-(des-dimetilamino)-tetraciclinas
US6432934B1 (en) * 1998-08-06 2002-08-13 Advanced Vision Research Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease
TWI290053B (en) * 2000-09-19 2007-11-21 Daiichi Seiyaku Co Medicinal composition for preventing the generation of a disagreeable taste
CN1843505A (zh) * 2005-04-06 2006-10-11 广州威尓曼新药开发中心有限公司 复方多西环素溶菌酶肠溶胶囊
WO2009052152A2 (en) * 2007-10-16 2009-04-23 Wyeth Tigecycline and methods of preparing intermediates
WO2010046932A2 (en) 2008-10-21 2010-04-29 Jubilant Organosys Limited Extended release pharmaceutical composition of minocycline and process thereof
JP2012520745A (ja) * 2009-03-20 2012-09-10 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 医療装置に抗菌活性を付与するための方法
CN102970992B (zh) * 2010-05-12 2016-07-06 莱姆派克斯制药公司 四环素组合物
CN103860474A (zh) * 2012-12-14 2014-06-18 青岛宝依特生物制药有限公司 一种多西环素可溶性粉的制备方法
PT108978B (pt) 2015-11-24 2020-03-09 Hovione Farm S A Sais de tetraciclinas

Also Published As

Publication number Publication date
HUE048839T2 (hu) 2020-08-28
PT108978A (pt) 2017-05-24
EP3365323B1 (en) 2020-01-01
JP6883578B2 (ja) 2021-06-09
ES2775702T3 (es) 2020-07-28
CA3005806A1 (en) 2017-06-01
AU2016358448B2 (en) 2020-07-16
CY1122679T1 (el) 2021-03-12
JP2019503993A (ja) 2019-02-14
EP3365323A1 (en) 2018-08-29
AU2016358448A1 (en) 2018-06-28
WO2017089809A1 (en) 2017-06-01
IL259572B (en) 2020-05-31
IL259572A (en) 2018-07-31
CN108602761B (zh) 2021-11-02
PT108978B (pt) 2020-03-09
US10543298B2 (en) 2020-01-28
US20180344903A1 (en) 2018-12-06
PL3365323T3 (pl) 2020-07-13
CN108602761A (zh) 2018-09-28

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