DK3280799T3 - Produktion af adeno-associerede vektorer i stor størrelse - Google Patents

Produktion af adeno-associerede vektorer i stor størrelse Download PDF

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Publication number
DK3280799T3
DK3280799T3 DK16767050.4T DK16767050T DK3280799T3 DK 3280799 T3 DK3280799 T3 DK 3280799T3 DK 16767050 T DK16767050 T DK 16767050T DK 3280799 T3 DK3280799 T3 DK 3280799T3
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DK
Denmark
Prior art keywords
adeno
sized
production
associated vectors
vectors
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DK16767050.4T
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Danish (da)
English (en)
Inventor
Sirkka Kyostio-Moore
David Souza
Karen Vincent
Original Assignee
Genzyme Corp
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56943906&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3280799(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
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Publication of DK3280799T3 publication Critical patent/DK3280799T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10041—Use of virus, viral particle or viral elements as a vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14151—Methods of production or purification of viral material
    • C12N2750/14152—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK16767050.4T 2015-04-08 2016-04-07 Produktion af adeno-associerede vektorer i stor størrelse DK3280799T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562144862P 2015-04-08 2015-04-08
US201562220067P 2015-09-17 2015-09-17
PCT/US2016/026486 WO2016164609A2 (en) 2015-04-08 2016-04-07 Production of oversized adeno-associated vectors

Publications (1)

Publication Number Publication Date
DK3280799T3 true DK3280799T3 (da) 2025-01-27

Family

ID=56943906

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16767050.4T DK3280799T3 (da) 2015-04-08 2016-04-07 Produktion af adeno-associerede vektorer i stor størrelse

Country Status (27)

Country Link
US (1) US10815497B2 (OSRAM)
EP (2) EP4512429A3 (OSRAM)
JP (3) JP6878299B2 (OSRAM)
KR (2) KR20250126875A (OSRAM)
CN (1) CN107864657A (OSRAM)
AU (3) AU2016245806A1 (OSRAM)
BR (1) BR112017021505A2 (OSRAM)
CA (1) CA2982123A1 (OSRAM)
CL (1) CL2017002537A1 (OSRAM)
CO (1) CO2017011344A2 (OSRAM)
CR (1) CR20170505A (OSRAM)
DK (1) DK3280799T3 (OSRAM)
EA (1) EA201792236A1 (OSRAM)
EC (1) ECSP17074016A (OSRAM)
ES (1) ES3008382T3 (OSRAM)
GT (1) GT201700214A (OSRAM)
HU (1) HUE069779T2 (OSRAM)
IL (3) IL283291B (OSRAM)
MX (1) MX2017012935A (OSRAM)
PE (1) PE20171800A1 (OSRAM)
PH (1) PH12017501836A1 (OSRAM)
PL (1) PL3280799T3 (OSRAM)
SG (3) SG10201912912QA (OSRAM)
TN (1) TN2017000431A1 (OSRAM)
TW (1) TWI707951B (OSRAM)
UY (1) UY36611A (OSRAM)
WO (1) WO2016164609A2 (OSRAM)

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Also Published As

Publication number Publication date
MX2017012935A (es) 2018-02-12
PL3280799T3 (pl) 2025-04-14
AU2022203942A1 (en) 2022-06-23
SG11201708203UA (en) 2017-11-29
NZ774736A (en) 2024-08-30
HK1246339A1 (en) 2018-09-07
KR20170133500A (ko) 2017-12-05
HUE069779T2 (hu) 2025-04-28
PE20171800A1 (es) 2017-12-28
WO2016164609A3 (en) 2016-12-15
JP6878299B2 (ja) 2021-05-26
SG10201912912QA (en) 2020-02-27
NZ737009A (en) 2024-01-26
SG10201909381WA (en) 2019-11-28
US20190048362A1 (en) 2019-02-14
ES3008382T3 (en) 2025-03-24
AU2016245806A1 (en) 2017-11-30
IL254933B (en) 2021-06-30
JP2023116678A (ja) 2023-08-22
CO2017011344A2 (es) 2018-03-28
UY36611A (es) 2016-11-30
JP2021118724A (ja) 2021-08-12
IL283291B (en) 2022-08-01
EP4512429A3 (en) 2025-05-21
CR20170505A (es) 2018-01-26
TWI707951B (zh) 2020-10-21
KR102848324B1 (ko) 2025-08-20
KR20250126875A (ko) 2025-08-25
WO2016164609A2 (en) 2016-10-13
BR112017021505A2 (pt) 2018-07-03
AU2024201619A1 (en) 2024-03-28
US10815497B2 (en) 2020-10-27
CL2017002537A1 (es) 2018-05-11
PH12017501836A1 (en) 2018-04-23
TN2017000431A1 (en) 2019-04-12
EP3280799B1 (en) 2024-10-30
EP3280799A2 (en) 2018-02-14
GT201700214A (es) 2018-10-24
JP2018510648A (ja) 2018-04-19
EP4512429A2 (en) 2025-02-26
AU2022203942B2 (en) 2023-12-14
CN107864657A (zh) 2018-03-30
TW201710498A (zh) 2017-03-16
IL254933A0 (en) 2017-12-31
ECSP17074016A (es) 2018-02-28
IL283291A (en) 2021-07-29
EA201792236A1 (ru) 2018-03-30
IL294965A (en) 2022-09-01
CA2982123A1 (en) 2016-10-13

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