DK32290A - APPLICATION OF 8'-ACYLED DERIVATIVES OF THE INTERMEDIATE COMPOUND MB-530A FOR THE PREPARATION OF A MEDICINE FOR TREATING HYPERCHOLESTEROLAEMIA - Google Patents
APPLICATION OF 8'-ACYLED DERIVATIVES OF THE INTERMEDIATE COMPOUND MB-530A FOR THE PREPARATION OF A MEDICINE FOR TREATING HYPERCHOLESTEROLAEMIA Download PDFInfo
- Publication number
- DK32290A DK32290A DK032290A DK32290A DK32290A DK 32290 A DK32290 A DK 32290A DK 032290 A DK032290 A DK 032290A DK 32290 A DK32290 A DK 32290A DK 32290 A DK32290 A DK 32290A
- Authority
- DK
- Denmark
- Prior art keywords
- acyled
- medicine
- derivatives
- preparation
- application
- Prior art date
Links
- 208000035150 Hypercholesterolemia Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55041292A JPH0692381B2 (en) | 1980-03-31 | 1980-03-31 | MB-530A derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
DK32290D0 DK32290D0 (en) | 1990-02-07 |
DK32290A true DK32290A (en) | 1990-02-07 |
Family
ID=12604367
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK145481A DK151273C (en) | 1980-03-31 | 1981-03-31 | PROCEDURE FOR THE PREPARATION OF THE CHOLESTEROL BIOSYNTHESE INHIBITOR MB-530A. |
DK032290A DK32290A (en) | 1980-03-31 | 1990-02-07 | APPLICATION OF 8'-ACYLED DERIVATIVES OF THE INTERMEDIATE COMPOUND MB-530A FOR THE PREPARATION OF A MEDICINE FOR TREATING HYPERCHOLESTEROLAEMIA |
DK032190A DK167805B1 (en) | 1980-03-31 | 1990-02-07 | INTERMEDIATE FOR THE PREPARATION OF CHOLESTEROL SYNTHESIS INHIBITORS |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK145481A DK151273C (en) | 1980-03-31 | 1981-03-31 | PROCEDURE FOR THE PREPARATION OF THE CHOLESTEROL BIOSYNTHESE INHIBITOR MB-530A. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK032190A DK167805B1 (en) | 1980-03-31 | 1990-02-07 | INTERMEDIATE FOR THE PREPARATION OF CHOLESTEROL SYNTHESIS INHIBITORS |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPH0692381B2 (en) |
AT (1) | ATA150781A (en) |
AU (1) | AU6893281A (en) |
BE (1) | BE888214A (en) |
CH (1) | CH646966A5 (en) |
DE (2) | DE3112566A1 (en) |
DK (3) | DK151273C (en) |
FI (1) | FI810991L (en) |
FR (1) | FR2479222A1 (en) |
GB (1) | GB2073193A (en) |
IE (1) | IE52367B1 (en) |
IT (1) | IT1144325B (en) |
MX (1) | MX9203567A (en) |
NL (1) | NL8101592A (en) |
SE (1) | SE461590B (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4472426A (en) * | 1982-12-22 | 1984-09-18 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
EP0215665B1 (en) * | 1985-09-13 | 1991-11-21 | Sankyo Company Limited | Hydroxy-ml-236b derivatives, their preparation and use |
US4997848A (en) * | 1987-10-27 | 1991-03-05 | Sankyo Company, Limited | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition |
US5075327A (en) * | 1988-08-10 | 1991-12-24 | Hoffmann-La Roche Inc. | Antipsoriatic agents |
US5021451A (en) * | 1988-11-14 | 1991-06-04 | Hoffman-La Roche Inc. | Method for inhibiting hyperproliferative diseases |
US5073568A (en) * | 1988-11-14 | 1991-12-17 | Hoffmann-La Roche Inc. | Antipsoriatic agents |
US5200549A (en) * | 1988-11-14 | 1993-04-06 | Hoffman-La Roche Inc. | Antipsoriatic agents |
US5159104A (en) * | 1991-05-01 | 1992-10-27 | Merck & Co., Inc. | Process to simvastatin ester |
FR2937537A1 (en) | 2008-10-29 | 2010-04-30 | Centre Nat Rech Scient | NANOPARTICLES OF STATIN |
KR101820099B1 (en) | 2013-01-18 | 2018-01-18 | 에스프린팅솔루션 주식회사 | resistive heat generating material, heating member and fusing device adopting the same |
JP2021509907A (en) * | 2018-01-09 | 2021-04-08 | リガンド・ファーマシューティカルズ・インコーポレイテッド | Acetal compounds and their therapeutic use |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5612114B2 (en) * | 1974-06-07 | 1981-03-18 | ||
JPS5925599B2 (en) * | 1979-02-20 | 1984-06-19 | 三共株式会社 | New physiologically active substance monacolin K and its production method |
AU535944B2 (en) * | 1979-06-15 | 1984-04-12 | Merck & Co., Inc. | Hypocholestermic fermentation products from aspergillus |
US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
US4282155A (en) * | 1980-02-04 | 1981-08-04 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
ZA81703B (en) * | 1980-02-04 | 1982-09-29 | Merck & Co Inc | New antihypercholesterolemic compounds,intermediates and processes |
AU548996B2 (en) * | 1980-02-04 | 1986-01-09 | Merck & Co., Inc. | Tetrahydro-2h-pyran-2-one derivatives |
PT72394B (en) * | 1980-02-04 | 1982-09-06 | Merck & Co Inc | Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics |
-
1980
- 1980-03-31 JP JP55041292A patent/JPH0692381B2/en not_active Expired - Lifetime
-
1981
- 1981-03-27 IE IE698/81A patent/IE52367B1/en not_active IP Right Cessation
- 1981-03-30 CH CH215381A patent/CH646966A5/en not_active IP Right Cessation
- 1981-03-30 DE DE19813112566 patent/DE3112566A1/en active Granted
- 1981-03-30 DE DE3153666A patent/DE3153666C2/en not_active Expired - Lifetime
- 1981-03-30 IT IT67438/81A patent/IT1144325B/en active
- 1981-03-31 NL NL8101592A patent/NL8101592A/en not_active Application Discontinuation
- 1981-03-31 AT AT0150781A patent/ATA150781A/en not_active IP Right Cessation
- 1981-03-31 SE SE8102047A patent/SE461590B/en not_active Application Discontinuation
- 1981-03-31 FI FI810991A patent/FI810991L/en not_active Application Discontinuation
- 1981-03-31 FR FR8106403A patent/FR2479222A1/en active Granted
- 1981-03-31 BE BE0/204328A patent/BE888214A/en not_active IP Right Cessation
- 1981-03-31 DK DK145481A patent/DK151273C/en not_active IP Right Cessation
- 1981-03-31 AU AU68932/81A patent/AU6893281A/en not_active Abandoned
- 1981-03-31 GB GB8110075A patent/GB2073193A/en not_active Withdrawn
-
1990
- 1990-02-07 DK DK032290A patent/DK32290A/en not_active Application Discontinuation
- 1990-02-07 DK DK032190A patent/DK167805B1/en not_active IP Right Cessation
-
1992
- 1992-06-26 MX MX9203567A patent/MX9203567A/en unknown
Also Published As
Publication number | Publication date |
---|---|
IT1144325B (en) | 1986-10-29 |
JPS56138181A (en) | 1981-10-28 |
IE810698L (en) | 1981-09-30 |
ATA150781A (en) | 1983-03-15 |
MX9203567A (en) | 1992-09-01 |
DE3112566A1 (en) | 1982-03-11 |
DE3112566C2 (en) | 1990-04-05 |
NL8101592A (en) | 1981-10-16 |
FI810991L (en) | 1981-10-01 |
FR2479222A1 (en) | 1981-10-02 |
SE461590B (en) | 1990-03-05 |
JPH0692381B2 (en) | 1994-11-16 |
IE52367B1 (en) | 1987-09-30 |
DK145481A (en) | 1981-10-01 |
SE8102047L (en) | 1981-10-01 |
DK32190A (en) | 1990-02-07 |
DK151273C (en) | 1988-07-04 |
BE888214A (en) | 1981-09-30 |
GB2073193A (en) | 1981-10-14 |
IT8167438A0 (en) | 1981-03-30 |
DK167805B1 (en) | 1993-12-20 |
DK32290D0 (en) | 1990-02-07 |
AU6893281A (en) | 1981-10-08 |
DE3153666C2 (en) | 1993-11-11 |
DK151273B (en) | 1987-11-16 |
DK32190D0 (en) | 1990-02-07 |
FR2479222B1 (en) | 1983-08-26 |
CH646966A5 (en) | 1984-12-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ARF | Application refused |