DK3213084T4 - Fremgangsmåde til berigelse af cirkulerende tumor dna - Google Patents
Fremgangsmåde til berigelse af cirkulerende tumor dna Download PDFInfo
- Publication number
- DK3213084T4 DK3213084T4 DK15790214.9T DK15790214T DK3213084T4 DK 3213084 T4 DK3213084 T4 DK 3213084T4 DK 15790214 T DK15790214 T DK 15790214T DK 3213084 T4 DK3213084 T4 DK 3213084T4
- Authority
- DK
- Denmark
- Prior art keywords
- enrichment
- procedure
- circulating tumor
- tumor dna
- dna
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7023—(Hyper)proliferation
- G01N2800/7028—Cancer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Electrochemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1419225.6A GB201419225D0 (en) | 2014-10-29 | 2014-10-29 | Method for the enrichment of circulating tumor DNA |
| GB201419299A GB201419299D0 (en) | 2014-10-30 | 2014-10-30 | Method for the enrichment of circulating tumour DNA |
| PCT/GB2015/053238 WO2016067029A1 (en) | 2014-10-29 | 2015-10-29 | Method for the enrichment of circulating tumor dna |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3213084T3 DK3213084T3 (da) | 2021-01-18 |
| DK3213084T4 true DK3213084T4 (da) | 2024-03-18 |
Family
ID=54427791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15790214.9T DK3213084T4 (da) | 2014-10-29 | 2015-10-29 | Fremgangsmåde til berigelse af cirkulerende tumor dna |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20180024141A1 (da) |
| EP (2) | EP3213084B2 (da) |
| JP (1) | JP6721599B2 (da) |
| CN (2) | CN107209190B (da) |
| AU (1) | AU2015340378B2 (da) |
| CA (1) | CA2965752C (da) |
| DK (1) | DK3213084T4 (da) |
| ES (1) | ES2839973T3 (da) |
| HK (1) | HK1243764A1 (da) |
| IL (1) | IL251896A0 (da) |
| PL (1) | PL3213084T3 (da) |
| SG (2) | SG10201903822XA (da) |
| WO (1) | WO2016067029A1 (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2930180T3 (es) | 2012-03-02 | 2022-12-07 | Sequenom Inc | Métodos para enriquecer ácido nucleico canceroso a partir de una muestra biológica |
| EP2971100A1 (en) | 2013-03-13 | 2016-01-20 | Sequenom, Inc. | Primers for dna methylation analysis |
| WO2015138774A1 (en) | 2014-03-13 | 2015-09-17 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| CN106544341A (zh) * | 2017-01-17 | 2017-03-29 | 上海亿康医学检验所有限公司 | 高效检测样本中的ctDNA的方法 |
| CN111433605B (zh) * | 2017-09-18 | 2023-09-08 | 圣特萨斯股份公司 | 用于针对循环无细胞dna纯化血液的方法和装置 |
| CN109932224A (zh) * | 2017-12-18 | 2019-06-25 | 中国科学院大连化学物理研究所 | 一种富集提取循环肿瘤dna的方法 |
| CN112119166A (zh) | 2018-03-13 | 2020-12-22 | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 无细胞dna染色质免疫沉淀的诊断应用 |
| CA3100345A1 (en) * | 2018-05-18 | 2019-11-21 | The Johns Hopkins University | Cell-free dna for assessing and/or treating cancer |
| GB201818965D0 (en) | 2018-11-21 | 2019-01-09 | Belgian Volition Sprl | Method for the detection of colorectal cancer |
| GB201818963D0 (en) | 2018-11-21 | 2019-01-09 | Belgian Volition Sprl | Methof for the detection of prostate cancer |
| CN109841265B (zh) * | 2019-02-22 | 2021-09-21 | 清华大学 | 使用片段化模式确定血浆游离核酸分子组织来源的方法和系统及应用 |
| GB201906201D0 (en) | 2019-05-02 | 2019-06-19 | Belgian Voltion Sprl | Method for the detection of protate cancer |
| GB201906199D0 (en) | 2019-05-02 | 2019-06-19 | Belgian Volition Sprl | Method for the detection of cancer |
| WO2021064463A1 (en) * | 2019-10-04 | 2021-04-08 | Santersus Ag | Method for isolating and analyzing cell free dna |
| JP7349104B2 (ja) * | 2019-11-13 | 2023-09-22 | 株式会社島津製作所 | ベロ毒素の検出方法 |
| MX2022006655A (es) | 2019-12-02 | 2022-09-07 | Belgian Volition Srl | Uso de nucleosomas libres de celulas como biomarcadores. |
| IL298458A (en) * | 2020-05-22 | 2023-01-01 | Aqtual Inc | Methods for characterizing cell-free nucleic acid fragments |
| GB202117799D0 (en) | 2021-12-09 | 2022-01-26 | Belgian Volition Srl | Method for the detection of blood cancer |
| WO2023122623A1 (en) * | 2021-12-21 | 2023-06-29 | Guardant Health, Inc. | Methods and systems for combinatorial chromatin-ip sequencing |
| US12053567B2 (en) | 2021-12-27 | 2024-08-06 | Santersus Ag | Method and device for removal of circulating cell free DNA |
| WO2023170298A1 (en) | 2022-03-11 | 2023-09-14 | Belgian Volition Srl | Differential diagnosis method |
| WO2024042210A1 (en) * | 2022-08-25 | 2024-02-29 | Belgian Volition Srl | Method for measuring cell free chromatin |
| WO2024148280A1 (en) | 2023-01-06 | 2024-07-11 | Ideaya Biosciences, Inc. | Treatment of er+ breast cancer comprising homologous recombination deficiency using parc inhibitor |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0319376D0 (en) † | 2003-08-18 | 2003-09-17 | Chroma Therapeutics Ltd | Histone modification detection |
| US20060115482A1 (en) * | 2004-04-27 | 2006-06-01 | The Regents Of The University Of California | Modifications of histone proteins as indicators of cell proliferation and differentiation |
| US20070243549A1 (en) * | 2006-04-12 | 2007-10-18 | Biocept, Inc. | Enrichment of circulating fetal dna |
| EP2062912A1 (en) * | 2007-11-26 | 2009-05-27 | Koninklijke Philips Electronics N.V. | Selective enrichment of post-translationally modified proteins and/or peptides |
| US20100240054A1 (en) * | 2008-09-22 | 2010-09-23 | Biocept, Inc. | Identification and isolation of fetal cells and nucleic acid |
| US20120094949A1 (en) * | 2009-04-14 | 2012-04-19 | The Regents Of The University Of California | Histone modification patterns for clinical diagnosis and prognosis of cancer |
| US20140213475A1 (en) * | 2011-07-14 | 2014-07-31 | University Of Massachusetts | Methods of diagnosing cancer using epigenetic biomarkers |
| GB201115098D0 (en) * | 2011-09-01 | 2011-10-19 | Belgian Volition Sa | Method for detecting nucleosomes containing histone variants |
| GB201115095D0 (en) | 2011-09-01 | 2011-10-19 | Singapore Volition Pte Ltd | Method for detecting nucleosomes containing nucleotides |
| EP2782928B1 (en) † | 2011-11-21 | 2017-01-04 | The Royal Institution for the Advancement of Learning / McGill University | Mutations of histone proteins associated with proliferative disorders |
| BR112014013082B1 (pt) | 2011-12-07 | 2021-02-02 | Singapore Volition Pte Limited | uso de um aduto nucleossomo-proteína e métodos para detectar a presença de um aduto nucleossomo-proteína |
| ES2930180T3 (es) * | 2012-03-02 | 2022-12-07 | Sequenom Inc | Métodos para enriquecer ácido nucleico canceroso a partir de una muestra biológica |
| US9388213B2 (en) * | 2012-09-10 | 2016-07-12 | The Rockefeller University | Polycomb repressive complex 2 (PRC2) inhibitors and uses thereof |
-
2015
- 2015-10-29 JP JP2017542357A patent/JP6721599B2/ja active Active
- 2015-10-29 PL PL15790214T patent/PL3213084T3/pl unknown
- 2015-10-29 SG SG10201903822XA patent/SG10201903822XA/en unknown
- 2015-10-29 EP EP15790214.9A patent/EP3213084B2/en active Active
- 2015-10-29 SG SG11201702978VA patent/SG11201702978VA/en unknown
- 2015-10-29 AU AU2015340378A patent/AU2015340378B2/en active Active
- 2015-10-29 US US15/523,280 patent/US20180024141A1/en not_active Abandoned
- 2015-10-29 CN CN201580058989.4A patent/CN107209190B/zh active Active
- 2015-10-29 WO PCT/GB2015/053238 patent/WO2016067029A1/en active Application Filing
- 2015-10-29 ES ES15790214T patent/ES2839973T3/es active Active
- 2015-10-29 DK DK15790214.9T patent/DK3213084T4/da active
- 2015-10-29 CN CN202010018617.1A patent/CN111505305B/zh active Active
- 2015-10-29 EP EP20203154.8A patent/EP3809140A1/en active Pending
- 2015-10-29 CA CA2965752A patent/CA2965752C/en active Active
-
2017
- 2017-04-25 IL IL251896A patent/IL251896A0/en active IP Right Grant
-
2018
- 2018-03-05 HK HK18103101.0A patent/HK1243764A1/zh active IP Right Maintenance
-
2022
- 2022-06-07 US US17/834,701 patent/US20220334128A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL251896A0 (en) | 2017-06-29 |
| EP3213084B2 (en) | 2023-12-13 |
| CA2965752A1 (en) | 2016-05-06 |
| EP3213084B1 (en) | 2020-11-25 |
| SG10201903822XA (en) | 2019-05-30 |
| NZ731116A (en) | 2024-03-22 |
| JP6721599B2 (ja) | 2020-07-15 |
| SG11201702978VA (en) | 2017-05-30 |
| ES2839973T3 (es) | 2021-07-06 |
| AU2015340378B2 (en) | 2021-08-12 |
| PL3213084T3 (pl) | 2021-07-26 |
| CN111505305A (zh) | 2020-08-07 |
| US20220334128A1 (en) | 2022-10-20 |
| DK3213084T3 (da) | 2021-01-18 |
| US20180024141A1 (en) | 2018-01-25 |
| CN107209190A (zh) | 2017-09-26 |
| CN111505305B (zh) | 2023-10-17 |
| EP3809140A1 (en) | 2021-04-21 |
| CN107209190B (zh) | 2021-07-16 |
| JP2017534300A (ja) | 2017-11-24 |
| EP3213084A1 (en) | 2017-09-06 |
| HK1243764A1 (zh) | 2018-07-20 |
| WO2016067029A1 (en) | 2016-05-06 |
| AU2015340378A1 (en) | 2017-05-11 |
| CA2965752C (en) | 2024-04-02 |
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