DK319685A - Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne - Google Patents
Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne Download PDFInfo
- Publication number
- DK319685A DK319685A DK319685A DK319685A DK319685A DK 319685 A DK319685 A DK 319685A DK 319685 A DK319685 A DK 319685A DK 319685 A DK319685 A DK 319685A DK 319685 A DK319685 A DK 319685A
- Authority
- DK
- Denmark
- Prior art keywords
- antibodies
- producing
- procedures
- hybridoma cells
- monoclonal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8132—Plasminogen activator inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8121—Serpins
- G01N2333/8132—Plasminogen activator inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK319685A DK319685A (da) | 1985-07-12 | 1985-07-12 | Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne |
EP86904118A EP0229126B1 (de) | 1985-07-12 | 1986-07-11 | Monoklonaler antikörper-inhibitor des plasminogenaktivators, hybridomen, herstellung monoklonaler antikörper und deren verwendung zur reinigung, beseitigung, inhibition oder zum testverfahren von inhibitoren |
JP50415186A JPS63500564A (ja) | 1985-07-12 | 1986-07-11 | モノクロ−ナル抗体 |
EP19930202290 EP0585995A1 (de) | 1985-07-12 | 1986-07-11 | Reiner menschlicher endothelbezüglicher Inhibitor von Plasminogen-aktivator (e-PAI) und ihre Herstellung |
PCT/DK1986/000080 WO1987000549A1 (en) | 1985-07-12 | 1986-07-11 | Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for purification, removal, inhibition or assay of the inhibitors |
DE3689766T DE3689766T2 (de) | 1985-07-12 | 1986-07-11 | Monoklonaler antikörper-inhibitor des plasminogenaktivators, hybridomen, herstellung monoklonaler antikörper und deren verwendung zur reinigung, beseitigung, inhibition oder zum testverfahren von inhibitoren. |
AU61446/86A AU6144686A (en) | 1985-07-12 | 1986-07-11 | Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for purification, removal, inhibition or assay of the inhibitors |
AT86904118T ATE103818T1 (de) | 1985-07-12 | 1986-07-11 | Monoklonaler antikoerper-inhibitor des plasminogenaktivators, hybridomen, herstellung monoklonaler antikoerper und deren verwendung zur reinigung, beseitigung, inhibition oder zum testverfahren von inhibitoren. |
US07/900,364 US5422245A (en) | 1985-07-12 | 1992-06-18 | Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for assay of the inhibitors |
US08/466,965 US6271352B1 (en) | 1985-07-12 | 1995-06-06 | PAI-1 determination and use thereof |
US09/922,718 US20020012950A1 (en) | 1985-07-12 | 2001-08-07 | Pai-1 determination and use thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK319685A DK319685A (da) | 1985-07-12 | 1985-07-12 | Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne |
Publications (2)
Publication Number | Publication Date |
---|---|
DK319685D0 DK319685D0 (da) | 1985-07-12 |
DK319685A true DK319685A (da) | 1987-01-13 |
Family
ID=8120155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK319685A DK319685A (da) | 1985-07-12 | 1985-07-12 | Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0229126B1 (de) |
JP (1) | JPS63500564A (de) |
AU (1) | AU6144686A (de) |
DE (1) | DE3689766T2 (de) |
DK (1) | DK319685A (de) |
WO (1) | WO1987000549A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4952512A (en) * | 1984-06-22 | 1990-08-28 | Loskutoff David J | Gene encoding an inhibitor of tissue-type and urokinase-type plasminogen activators |
FI89634C (fi) * | 1987-07-10 | 1993-10-25 | Yamanouchi Pharma Co Ltd | Foerfarande, anordning och kitt foer maetning av vaevnadsplasminogenaktivator-aktivitet |
DE3742997A1 (de) * | 1987-12-18 | 1989-06-29 | Behringwerke Ag | Peptide, verfahren zu ihrer herstellung, ihre verwendung zur gewinnung von antikoerpern sowie deren verwendung zur blockierung der pai-1-aktivitaet menschlichen blutes |
DK160189A (da) * | 1988-04-04 | 1989-10-05 | Teijin Ltd | Reagenssystem til immunologisk analyse af kompleks af human plasminogenaktivatorinhibitor og human vaevsplasminogenaktivator, analysesaet dertil samt monoklone antistoffer og hybridomer |
JP2750732B2 (ja) * | 1988-04-04 | 1998-05-13 | 帝人株式会社 | ヒトプラスミノーゲンアクティベーターインヒビター・1−ヒト組織プラスミノーゲンアクティベーター複合体の免疫学的測定方法 |
JP2868530B2 (ja) * | 1989-04-03 | 1999-03-10 | 帝人株式会社 | プラスミノーゲンアクティベーターインヒビターに対するモノクローナル抗体 |
DK0467932T3 (da) * | 1989-04-07 | 2001-02-12 | Cancerforskningsfonden Af 1989 | Plasminogen-aktivator-receptor af urokinasetypen |
AU633366B2 (en) * | 1989-10-02 | 1993-01-28 | Teijin Limited | Human tissue plasminogen activator-human plasminogen activator inhibitor complex immunoassay and kit therefor |
DK85193D0 (da) * | 1993-07-16 | 1993-07-16 | Cancerforskningsfondet Af 1989 | Suppression of inhibitors |
ES2770507T3 (es) * | 2013-08-13 | 2020-07-01 | Sanofi Sa | Anticuerpos dirigidos contra el inhibidor de los activadores del plasminógeno de tipo 1 (PAI-1) y usos de los mismos |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE896543A (fr) * | 1983-04-22 | 1983-08-16 | Wallone Region | Ensembles d'anticorps monoclonaux deriges contre les proteines humaines impliquees dans la coagulation et la fibrinolyse du sang |
US4791068A (en) * | 1984-06-22 | 1988-12-13 | Scripps Clinic And Research Foundation | Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators |
DE3586577T2 (de) * | 1984-07-26 | 1993-03-25 | Teijin Ltd | Immunologische bestimmung von menschlichem plasmin/alpha-2-plasmin-hemmstoff. |
JP5249920B2 (ja) * | 2007-07-05 | 2013-07-31 | パナソニック株式会社 | データ処理装置、データ処理方法、データ処理プログラム、記録媒体及び集積回路 |
-
1985
- 1985-07-12 DK DK319685A patent/DK319685A/da not_active Application Discontinuation
-
1986
- 1986-07-11 EP EP86904118A patent/EP0229126B1/de not_active Expired - Lifetime
- 1986-07-11 DE DE3689766T patent/DE3689766T2/de not_active Expired - Lifetime
- 1986-07-11 WO PCT/DK1986/000080 patent/WO1987000549A1/en active IP Right Grant
- 1986-07-11 JP JP50415186A patent/JPS63500564A/ja active Pending
- 1986-07-11 AU AU61446/86A patent/AU6144686A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE3689766D1 (de) | 1994-05-11 |
WO1987000549A1 (en) | 1987-01-29 |
AU6144686A (en) | 1987-02-10 |
EP0229126A1 (de) | 1987-07-22 |
DE3689766T2 (de) | 1994-12-01 |
DK319685D0 (da) | 1985-07-12 |
EP0229126B1 (de) | 1994-04-06 |
JPS63500564A (ja) | 1988-03-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |