DK3196300T3 - Mikroorganisme med forbedret L-lysin-produktivitet og fremgangsmåde til fremstilling af L-lysin under anvendelse af samme - Google Patents

Mikroorganisme med forbedret L-lysin-produktivitet og fremgangsmåde til fremstilling af L-lysin under anvendelse af samme Download PDF

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Publication number
DK3196300T3
DK3196300T3 DK15837358.9T DK15837358T DK3196300T3 DK 3196300 T3 DK3196300 T3 DK 3196300T3 DK 15837358 T DK15837358 T DK 15837358T DK 3196300 T3 DK3196300 T3 DK 3196300T3
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Denmark
Prior art keywords
lysine
microorganism
producing
improved
same
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DK15837358.9T
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English (en)
Inventor
Lan Huh
Kwang Ho Lee
Hyung Joon Kim
Jun Ok Moon
Song-Gi Ryu
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Cj Cheiljedang Corp
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Publication of DK3196300T3 publication Critical patent/DK3196300T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1247DNA-directed RNA polymerase (2.7.7.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07Nucleotidyltransferases (2.7.7)
    • C12Y207/07006DNA-directed RNA polymerase (2.7.7.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15Corynebacterium

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
DK15837358.9T 2014-09-05 2015-09-04 Mikroorganisme med forbedret L-lysin-produktivitet og fremgangsmåde til fremstilling af L-lysin under anvendelse af samme DK3196300T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020140119137A KR101755767B1 (ko) 2014-09-05 2014-09-05 L-라이신 생산능이 향상된 미생물 및 이를 이용한 l-라이신 생산방법
PCT/KR2015/009353 WO2016036191A1 (ko) 2014-09-05 2015-09-04 L-라이신 생산능이 향상된 미생물 및 이를 이용한 l-라이신 생산방법

Publications (1)

Publication Number Publication Date
DK3196300T3 true DK3196300T3 (da) 2022-07-25

Family

ID=55440139

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15837358.9T DK3196300T3 (da) 2014-09-05 2015-09-04 Mikroorganisme med forbedret L-lysin-produktivitet og fremgangsmåde til fremstilling af L-lysin under anvendelse af samme

Country Status (12)

Country Link
US (1) US10676512B2 (da)
EP (1) EP3196300B1 (da)
JP (1) JP6464260B2 (da)
KR (1) KR101755767B1 (da)
CN (2) CN111676205B (da)
BR (1) BR112017004368A2 (da)
DK (1) DK3196300T3 (da)
ES (1) ES2917498T3 (da)
MY (1) MY180044A (da)
PL (1) PL3196300T3 (da)
RU (1) RU2668176C1 (da)
WO (1) WO2016036191A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102291553B1 (ko) * 2021-01-29 2021-08-18 씨제이제일제당 (주) 신규한 프리모솜 조립 단백질 변이체 및 이를 이용한 l-라이신 생산 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69637684D1 (de) * 1995-05-30 2008-10-30 Astrazeneca Ab Dna moleküle
DE10162729A1 (de) * 2001-12-20 2003-07-03 Degussa Allele des sigA-Gens aus coryneformen Bakterien
ATE443757T1 (de) * 2004-01-30 2009-10-15 Ajinomoto Kk L-aminosäure produzierender mikroorganismus und verfahren zur l-aminosäureproduktion
DE602005021757D1 (de) 2004-03-05 2010-07-22 Kao Corp Zur gattung bacillus gehörendes mutantes bakterium
US8735132B2 (en) 2010-05-07 2014-05-27 Massachusetts Institute Of Technology Mutations and genetic targets for enhanced L-tyrosine production
CN105483145B (zh) 2011-12-21 2021-04-06 Cj第一制糖株式会社 利用具有产生l-赖氨酸能力的微生物产生l-赖氨酸的方法
BR112014017088B1 (pt) 2012-01-10 2022-04-19 Cj Cheiljedang Corporation Microrganismos de corynebacterium que podem utilizar xilose e método para a produção de l-lisina utilizando os mesmos

Also Published As

Publication number Publication date
US10676512B2 (en) 2020-06-09
CN111676205B (zh) 2023-11-07
EP3196300A1 (en) 2017-07-26
MY180044A (en) 2020-11-20
PL3196300T3 (pl) 2022-08-01
EP3196300B1 (en) 2022-05-11
JP6464260B2 (ja) 2019-02-06
KR20160029964A (ko) 2016-03-16
ES2917498T3 (es) 2022-07-08
BR112017004368A2 (pt) 2018-02-27
WO2016036191A1 (ko) 2016-03-10
CN106715688A (zh) 2017-05-24
EP3196300A4 (en) 2018-01-31
US20180037615A1 (en) 2018-02-08
RU2668176C1 (ru) 2018-09-26
CN111676205A (zh) 2020-09-18
JP2017525381A (ja) 2017-09-07
KR101755767B1 (ko) 2017-07-10

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