DK3174976T3 - Fremgangsmåder og systemer til forarbejdning af partikler - Google Patents
Fremgangsmåder og systemer til forarbejdning af partikler Download PDFInfo
- Publication number
- DK3174976T3 DK3174976T3 DK15827324.3T DK15827324T DK3174976T3 DK 3174976 T3 DK3174976 T3 DK 3174976T3 DK 15827324 T DK15827324 T DK 15827324T DK 3174976 T3 DK3174976 T3 DK 3174976T3
- Authority
- DK
- Denmark
- Prior art keywords
- systems
- processing methods
- particle processing
- particle
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462032520P | 2014-08-01 | 2014-08-01 | |
PCT/US2015/043500 WO2016019393A1 (en) | 2014-08-01 | 2015-08-03 | Methods and systems for processing particles |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3174976T3 true DK3174976T3 (da) | 2020-11-23 |
Family
ID=55218409
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15827324.3T DK3174976T3 (da) | 2014-08-01 | 2015-08-03 | Fremgangsmåder og systemer til forarbejdning af partikler |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP3174976B1 (da) |
DK (1) | DK3174976T3 (da) |
ES (1) | ES2839998T3 (da) |
WO (1) | WO2016019393A1 (da) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105264127B (zh) | 2013-03-15 | 2019-04-09 | Gpb科学有限责任公司 | 颗粒的片上微流体处理 |
US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
CN113512522A (zh) | 2013-03-15 | 2021-10-19 | 普林斯顿大学理事会 | 用于高通量纯化的方法和设备 |
US9925281B2 (en) | 2014-08-05 | 2018-03-27 | Case Western Reserve University | Coated plant virus imaging agents |
WO2016073972A1 (en) | 2014-11-07 | 2016-05-12 | Case Western Reserve University | Cancer immunotherapy using virus particles |
US11617787B2 (en) | 2014-11-07 | 2023-04-04 | Case Western Reserve University | Cancer immunotherapy using virus particles |
EP3313527B1 (en) | 2015-06-29 | 2021-02-24 | Case Western Reserve University | Anticancer drug-containing plant virus particles |
EP3322485B1 (en) | 2015-07-16 | 2020-07-01 | Case Western Reserve University | Plant virus particles for delivery of antimitotic agents |
WO2017197343A2 (en) * | 2016-05-12 | 2017-11-16 | 10X Genomics, Inc. | Microfluidic on-chip filters |
US11654117B2 (en) * | 2016-11-03 | 2023-05-23 | Case Western Reserve University | Melt processed viral nanoparticle constructs |
EP3545305B1 (en) | 2016-11-24 | 2020-05-20 | Koninklijke Philips N.V. | Device, system method and kit for isolating an analyte from a body fluid sample |
US11590183B2 (en) | 2017-03-10 | 2023-02-28 | Case Western Reserve University | Cancer immunotherapy using virus particles |
US11672840B2 (en) | 2017-05-17 | 2023-06-13 | Case Western Reserve University | Anticancer trail-targeted plant virus particles |
AU2018323875A1 (en) * | 2017-09-01 | 2020-04-23 | Gpb Scientific, Inc. | Methods for preparing therapeutically active cells using microfluidics |
CN107603850A (zh) * | 2017-10-13 | 2018-01-19 | 深圳先进技术研究院 | 用于细胞分选的微流控装置及其制备方法 |
WO2019084555A1 (en) | 2017-10-27 | 2019-05-02 | Case Western Reserve University | TYMOVIRUS VIRUSES AND VIRAL TYPE PARTICLES USEFUL AS NANOVECTORS FOR IMAGING AND THERAPEUTIC AGENTS |
EP3647767A1 (de) * | 2018-10-30 | 2020-05-06 | Siemens Healthcare GmbH | Isovolumetrisches aufkugeln von roten blutzellen |
US11896676B2 (en) | 2019-08-07 | 2024-02-13 | Case Western Reserve University | Targeting cancer cells and tissue using filamentous plant virus particles |
US20230033651A1 (en) * | 2020-01-08 | 2023-02-02 | The General Hospital Corporation | Microfluidic systems and methods for low-shear isolation of rare cells from large sample volumes |
CN114594170A (zh) * | 2020-12-03 | 2022-06-07 | 复旦大学 | 一种磁固相萃取结合快速原位衍生化的体内药物分析方法 |
CN113695748B (zh) * | 2021-08-23 | 2022-10-25 | 西安交通大学 | 一种基于空间光调制器的鲨鱼皮表面结构快速制备方法 |
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US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
US5216141A (en) | 1988-06-06 | 1993-06-01 | Benner Steven A | Oligonucleotide analogs containing sulfur linkages |
US5386023A (en) | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
US5602240A (en) | 1990-07-27 | 1997-02-11 | Ciba Geigy Ag. | Backbone modified oligonucleotide analogs |
US5644048A (en) | 1992-01-10 | 1997-07-01 | Isis Pharmaceuticals, Inc. | Process for preparing phosphorothioate oligonucleotides |
US5427663A (en) | 1993-06-08 | 1995-06-27 | British Technology Group Usa Inc. | Microlithographic array for macromolecule and cell fractionation |
US5637684A (en) | 1994-02-23 | 1997-06-10 | Isis Pharmaceuticals, Inc. | Phosphoramidate and phosphorothioamidate oligomeric compounds |
AU2002230979A1 (en) | 2000-12-18 | 2002-07-01 | Trustees Of Princeton University | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis |
US7704728B2 (en) * | 2001-07-18 | 2010-04-27 | The University Of Michigan | Microfluidic gravity pump with constant flow rate |
WO2003066191A1 (en) | 2002-02-04 | 2003-08-14 | Colorado School Of Mines | Laminar flow-based separations of colloidal and cellular particles |
EP2359689B1 (en) | 2002-09-27 | 2015-08-26 | The General Hospital Corporation | Microfluidic device for cell separation and use thereof |
WO2004037374A2 (en) | 2002-10-23 | 2004-05-06 | The Trustees Of Princeton University | Method for continuous particle separation using obstacle arrays asymmetrically aligned to fields |
US20070026417A1 (en) * | 2005-07-29 | 2007-02-01 | Martin Fuchs | Devices and methods for enrichment and alteration of circulating tumor cells and other particles |
US20070196820A1 (en) | 2005-04-05 | 2007-08-23 | Ravi Kapur | Devices and methods for enrichment and alteration of cells and other particles |
US7735652B2 (en) | 2006-06-01 | 2010-06-15 | The Trustees Of Princeton University | Apparatus and method for continuous particle separation |
US8579117B2 (en) | 2008-07-24 | 2013-11-12 | The Trustees Of Princeton University | Bump array device having asymmetric gaps for segregation of particles |
US9090663B2 (en) * | 2009-04-21 | 2015-07-28 | The Trustees Of Columbia University In The City Of New York | Systems and methods for the capture and separation of microparticles |
EP2421628A4 (en) * | 2009-04-23 | 2012-10-10 | Logos Energy Inc | LATERAL DISPLACEMENT ARRANGEMENT FOR MICROFILTRATION |
US8801922B2 (en) * | 2009-06-24 | 2014-08-12 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Dialysis system |
US8830451B1 (en) | 2010-05-07 | 2014-09-09 | Stc.Unm | Multinode acoustic focusing for parallel flow cytometry analysis applications |
CN103119441A (zh) | 2010-08-15 | 2013-05-22 | Gpb科学有限责任公司 | 血液分析中的微流体细胞分离 |
CN103889556A (zh) | 2011-01-06 | 2014-06-25 | Gpb科学有限责任公司 | 在引入亲和性和大小两者的微流体芯片上的循环肿瘤细胞捕获 |
WO2012149472A2 (en) | 2011-04-27 | 2012-11-01 | Ignite Institute For Individualized Health | Methods, compositions, and kits for treating and preventing neurological conditions |
EP2739394A2 (en) | 2011-08-04 | 2014-06-11 | Sage Science, Inc. | Microfluidic systems and methods for processing fluids |
EP2897730A4 (en) * | 2012-09-21 | 2016-04-27 | Massachusetts Inst Technology | MICROFLUIDIC DEVICE AND USES THEREOF |
US9804068B2 (en) * | 2012-09-28 | 2017-10-31 | University Of Maryland | Particle separation and concentration using spiral inertial filtration |
-
2015
- 2015-08-03 EP EP15827324.3A patent/EP3174976B1/en active Active
- 2015-08-03 ES ES15827324T patent/ES2839998T3/es active Active
- 2015-08-03 DK DK15827324.3T patent/DK3174976T3/da active
- 2015-08-03 WO PCT/US2015/043500 patent/WO2016019393A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
EP3174976A1 (en) | 2017-06-07 |
ES2839998T3 (es) | 2021-07-06 |
WO2016019393A1 (en) | 2016-02-04 |
EP3174976B1 (en) | 2020-10-28 |
EP3174976A4 (en) | 2018-01-17 |
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