DK3174532T3 - Pulverformede, direkte komprimerbare typer af polyvinylalkohol - Google Patents

Pulverformede, direkte komprimerbare typer af polyvinylalkohol Download PDF

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Publication number
DK3174532T3
DK3174532T3 DK15735852.4T DK15735852T DK3174532T3 DK 3174532 T3 DK3174532 T3 DK 3174532T3 DK 15735852 T DK15735852 T DK 15735852T DK 3174532 T3 DK3174532 T3 DK 3174532T3
Authority
DK
Denmark
Prior art keywords
polyvinyl alcohol
direct compressible
powdered
types
powdered direct
Prior art date
Application number
DK15735852.4T
Other languages
English (en)
Inventor
Finn Bauer
Thorsten Wedel
Guenter Moddelmog
Roberto Ognibene
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK3174532T3 publication Critical patent/DK3174532T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK15735852.4T 2014-07-30 2015-07-03 Pulverformede, direkte komprimerbare typer af polyvinylalkohol DK3174532T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14002664 2014-07-30
PCT/EP2015/001357 WO2016015814A1 (de) 2014-07-30 2015-07-03 Pulverförmige, direkt verpressbare polyvinlalkohol-typen

Publications (1)

Publication Number Publication Date
DK3174532T3 true DK3174532T3 (da) 2020-08-17

Family

ID=51260567

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15735852.4T DK3174532T3 (da) 2014-07-30 2015-07-03 Pulverformede, direkte komprimerbare typer af polyvinylalkohol

Country Status (13)

Country Link
US (1) US11040012B2 (da)
EP (1) EP3174532B1 (da)
JP (1) JP6713450B2 (da)
KR (1) KR20170038039A (da)
CN (1) CN106659793A (da)
AU (1) AU2015295847B2 (da)
BR (1) BR112017001749A2 (da)
CA (1) CA2956540C (da)
DK (1) DK3174532T3 (da)
ES (1) ES2811120T3 (da)
IL (1) IL250136B (da)
PT (1) PT3174532T (da)
WO (1) WO2016015814A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2998422A1 (en) 2015-09-14 2017-03-23 Merck Patent Gmbh Formulation having controlled, delayed release of active ingredient
JP7082067B2 (ja) * 2016-05-13 2022-06-07 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 溶融押出用途のためのポリマーの粒子サイズおよび分布
WO2018083285A1 (en) * 2016-11-07 2018-05-11 Merck Patent Gmbh Controlled release tablet based on polyvinyl alcohol and its manufacturing
US20190307698A1 (en) 2016-12-14 2019-10-10 Merck Patent Gmbh Directly compressible matrix for the production of tablets having extended release of active pharmaceutical ingredient
WO2021148362A1 (en) * 2020-01-21 2021-07-29 Merck Patent Gmbh Directly compressible polymer combinations for matrix tablets with extended drug release

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990335A (en) * 1987-03-25 1991-02-05 E. I. Du Pont De Nemours And Company Use of vinyl alcohol homopolymer and copolymers for tableting active materials
EP0359746B1 (en) * 1987-03-25 1992-06-03 E.I. Du Pont De Nemours And Company Use of vinyl alcohol homopolymers and copolymers for tableting active materials
US5733578A (en) 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
ES2282492T3 (es) * 2001-11-30 2007-10-16 Pfizer Products Inc. Composiciones farmaceuticas de liberacion controlada orales de 5,8,14-triazatetraciclo (10.3.1.0(2,11).0(4,9)-hexadeca-2(11)3,5,7,9-pentaeno.
AU2003254914A1 (en) * 2002-08-12 2004-03-03 Kyowa Hakko Kogyo Co., Ltd. Amino acid-containing chewable
JP4947482B2 (ja) * 2003-11-14 2012-06-06 味の素株式会社 フェニルアラニン誘導体の徐放性経口投与製剤
US20060177380A1 (en) * 2004-11-24 2006-08-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of orally administered pharmaceutical products
US20080152595A1 (en) * 2004-11-24 2008-06-26 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of orally administered pharmaceutical products
RU2008104638A (ru) * 2005-07-07 2009-08-20 Фарнэм Компаниз, Инк. (Us) Фармацевтические композиции хорошо растворимых в воде лекарственных средств, обеспечивающих их замедленное высвобождение
KR100762847B1 (ko) 2006-01-27 2007-10-04 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
NZ573174A (en) * 2006-06-01 2012-01-12 Msd Consumer Care Inc Sustained release pharmaceutical dosage form containing phenylephrine
US8956662B2 (en) 2006-06-01 2015-02-17 Msd Consumer Care, Inc. Phenylephrine pharmaceutical formulations and compositions for colonic absorption
WO2008020990A1 (en) * 2006-08-09 2008-02-21 Mallinckrodt Baker, Inc. New direct compressible excipient blend
US20080138404A1 (en) * 2006-12-06 2008-06-12 Biovail Laboratories International S.R.L. Extended release formulations of carvedilol
JP6245786B2 (ja) * 2011-10-17 2017-12-13 大同化成工業株式会社 医薬用結合剤及び該結合剤を用いた製剤
EP3173101B1 (en) * 2014-07-25 2020-10-21 Mitsubishi Chemical Corporation Polyvinyl alcohol particles, pharmaceutical binder using same, pharmaceutical tablet, sustained-release pharmaceutical tablet, and method for producing polyvinyl alcohol particles

Also Published As

Publication number Publication date
IL250136B (en) 2020-08-31
US20180207101A1 (en) 2018-07-26
EP3174532B1 (de) 2020-05-13
JP2017521473A (ja) 2017-08-03
US11040012B2 (en) 2021-06-22
CA2956540C (en) 2023-01-03
IL250136A0 (en) 2017-03-30
JP6713450B2 (ja) 2020-06-24
CN106659793A (zh) 2017-05-10
BR112017001749A2 (pt) 2017-11-21
PT3174532T (pt) 2020-08-13
WO2016015814A1 (de) 2016-02-04
KR20170038039A (ko) 2017-04-05
AU2015295847A1 (en) 2017-03-23
EP3174532A1 (de) 2017-06-07
ES2811120T3 (es) 2021-03-10
AU2015295847B2 (en) 2020-06-18
CA2956540A1 (en) 2016-02-04

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