DK3173420T3 - Polypeptid og polypeptidkompleks til undertrykkelse af tumormetastase og behandling af leukæmi samt fremgangsmåde til fremstilling deraf og anvendelse deraf - Google Patents

Polypeptid og polypeptidkompleks til undertrykkelse af tumormetastase og behandling af leukæmi samt fremgangsmåde til fremstilling deraf og anvendelse deraf Download PDF

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Publication number
DK3173420T3
DK3173420T3 DK15824964.9T DK15824964T DK3173420T3 DK 3173420 T3 DK3173420 T3 DK 3173420T3 DK 15824964 T DK15824964 T DK 15824964T DK 3173420 T3 DK3173420 T3 DK 3173420T3
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DK
Denmark
Prior art keywords
polypeptid
metastase
leukemia
complex
procedure
Prior art date
Application number
DK15824964.9T
Other languages
English (en)
Inventor
Chen Wang
Hongyang Duan
Yanlian Yang
Haiyan Xu
Xiaojin Li
Hua Guo
Hanyi Xie
Yue Yu
Original Assignee
Nat Ct Nanoscience & Technology China
Inst Basic Medical Sciences Cams
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201410353810.5A external-priority patent/CN104098652B/zh
Priority claimed from CN201410497974.5A external-priority patent/CN104231050A/zh
Application filed by Nat Ct Nanoscience & Technology China, Inst Basic Medical Sciences Cams filed Critical Nat Ct Nanoscience & Technology China
Application granted granted Critical
Publication of DK3173420T3 publication Critical patent/DK3173420T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15824964.9T 2014-07-23 2015-07-01 Polypeptid og polypeptidkompleks til undertrykkelse af tumormetastase og behandling af leukæmi samt fremgangsmåde til fremstilling deraf og anvendelse deraf DK3173420T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201410353810.5A CN104098652B (zh) 2014-07-23 2014-07-23 一种抑制肿瘤转移的多肽和多肽复合物、其制备方法及其应用
CN201410497974.5A CN104231050A (zh) 2014-09-25 2014-09-25 一种抑制肿瘤转移和治疗白血病的多肽和多肽复合物、其制备方法及其应用
PCT/CN2015/083021 WO2016011878A1 (zh) 2014-07-23 2015-07-01 一种抑制肿瘤转移和治疗白血病的多肽和多肽复合物、其制备方法及其应用

Publications (1)

Publication Number Publication Date
DK3173420T3 true DK3173420T3 (da) 2021-10-18

Family

ID=55162493

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15824964.9T DK3173420T3 (da) 2014-07-23 2015-07-01 Polypeptid og polypeptidkompleks til undertrykkelse af tumormetastase og behandling af leukæmi samt fremgangsmåde til fremstilling deraf og anvendelse deraf

Country Status (5)

Country Link
US (1) US10258669B2 (da)
EP (1) EP3173420B1 (da)
CN (1) CN106029683B (da)
DK (1) DK3173420T3 (da)
WO (1) WO2016011878A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111349144A (zh) * 2018-12-24 2020-06-30 天津农学院 一种在牛蛙中提取抗肿瘤多肽及分析方法
CN109865125B (zh) * 2019-03-05 2021-08-20 陕西省人民医院 调节肽与曼宋酮e在制备治疗改进的白血病药物及其用途
CN111808173B (zh) * 2019-04-12 2024-02-23 国家纳米科学中心 多肽-量子点复合物、其制备方法及应用
CN114478693B (zh) * 2020-11-11 2024-03-19 上海市肿瘤研究所 一种具有抑制肿瘤转移活性的多肽分子、制备方法及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) * 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US6914131B1 (en) * 1998-10-09 2005-07-05 Chiron S.R.L. Neisserial antigens
US20040031072A1 (en) * 1999-05-06 2004-02-12 La Rosa Thomas J. Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
MXPA05009178A (es) * 2003-02-27 2006-03-08 Northwest Biotherapeutics Inc Generacion de celulas dendriticas a partir de celulas precursoras dendriticas monociticas con gm-csf en ausencia de citocinas adicionales.
CN102002106A (zh) 2010-05-20 2011-04-06 郑州大学 融合蛋白mbp-nap及其制备方法和应用
CN102060913B (zh) 2010-11-30 2012-09-05 暨南大学 一种与人血清白蛋白结合的七肽与应用
GB201108108D0 (en) 2011-05-16 2011-06-29 Syntaxin Ltd Therapeutic fusion proteins
CN104098652B (zh) 2014-07-23 2016-11-09 国家纳米科学中心 一种抑制肿瘤转移的多肽和多肽复合物、其制备方法及其应用
CN104231050A (zh) 2014-09-25 2014-12-24 国家纳米科学中心 一种抑制肿瘤转移和治疗白血病的多肽和多肽复合物、其制备方法及其应用

Also Published As

Publication number Publication date
US10258669B2 (en) 2019-04-16
EP3173420A1 (en) 2017-05-31
US20170360897A1 (en) 2017-12-21
EP3173420B1 (en) 2021-09-08
CN106029683B (zh) 2020-11-10
CN106029683A (zh) 2016-10-12
WO2016011878A1 (zh) 2016-01-28
EP3173420A4 (en) 2018-06-27

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