DK3124040T3 - Il-6 til terapi af kemoterapi-induceret neuropati - Google Patents

Il-6 til terapi af kemoterapi-induceret neuropati Download PDF

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Publication number
DK3124040T3
DK3124040T3 DK16188978.7T DK16188978T DK3124040T3 DK 3124040 T3 DK3124040 T3 DK 3124040T3 DK 16188978 T DK16188978 T DK 16188978T DK 3124040 T3 DK3124040 T3 DK 3124040T3
Authority
DK
Denmark
Prior art keywords
chemotherapy
therapy
induced neuropathy
neuropathy
induced
Prior art date
Application number
DK16188978.7T
Other languages
English (en)
Inventor
Michel Dreano
Pierre-Alain Vitte
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Application granted granted Critical
Publication of DK3124040T3 publication Critical patent/DK3124040T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
DK16188978.7T 2004-04-29 2005-04-28 Il-6 til terapi af kemoterapi-induceret neuropati DK3124040T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL16167304A IL161673A0 (en) 2004-04-29 2004-04-29 Compositions and methods for therapy of chemotherapy-induced neuropathy
EP05737409.2A EP1740200B1 (en) 2004-04-29 2005-04-28 Il-6 for therapy or prevention of chemotherapy-induced neuropathy

Publications (1)

Publication Number Publication Date
DK3124040T3 true DK3124040T3 (da) 2020-04-20

Family

ID=34074041

Family Applications (2)

Application Number Title Priority Date Filing Date
DK05737409.2T DK1740200T3 (da) 2004-04-29 2005-04-28 Il-6 til terapi eller forebyggelse af kemoterapi-induceret neuropati
DK16188978.7T DK3124040T3 (da) 2004-04-29 2005-04-28 Il-6 til terapi af kemoterapi-induceret neuropati

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK05737409.2T DK1740200T3 (da) 2004-04-29 2005-04-28 Il-6 til terapi eller forebyggelse af kemoterapi-induceret neuropati

Country Status (11)

Country Link
US (1) US7951359B2 (da)
EP (2) EP1740200B1 (da)
JP (1) JP2007534746A (da)
AU (1) AU2005237324A1 (da)
CA (1) CA2564390A1 (da)
DK (2) DK1740200T3 (da)
ES (2) ES2788131T3 (da)
IL (2) IL161673A0 (da)
NO (1) NO20065471L (da)
PL (2) PL3124040T3 (da)
WO (1) WO2005105135A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL163856A0 (en) * 2004-09-01 2005-12-18 Applied Research Systems Use of IL-6 in vascular complications
AU2008331109B2 (en) * 2007-11-28 2014-04-10 Christian-Albrechts-Universitat Zu Kiel Methods for the treatment of radiation or chemotherapy-induced tissue damage
US20130230580A1 (en) * 2010-09-14 2013-09-05 Paul S. Frenette Administration of SNS Neuroprotective Agents to Promote Hematopoietic Regeneration
EP3299032A1 (en) 2016-09-23 2018-03-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Inhibitors of gpr132 for use in preventing and/or treating chemotherapy-induced neuropathic pain
US20190381138A1 (en) * 2018-05-17 2019-12-19 Helixmith Co., Ltd. Treatment of neuropathic pain associated with chemotherapy-induced peripheral neuropathy
WO2022256688A1 (en) * 2021-06-04 2022-12-08 Sonnet BioTherapeutics, Inc. Methods of treating age-related frailty with interleukin-6

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US4588585A (en) 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4737462A (en) 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4959314A (en) 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5116943A (en) 1985-01-18 1992-05-26 Cetus Corporation Oxidation-resistant muteins of Il-2 and other protein
US5017691A (en) 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US4879111A (en) 1986-04-17 1989-11-07 Cetus Corporation Treatment of infections with lymphokines
US4965195A (en) 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4904584A (en) 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
JP3501286B2 (ja) 1989-12-22 2004-03-02 アプライド リサーチ システムズ，エーアールエス ホールディング ナームロゼ ベノートスハップ 一定の細胞系又は微生物の内因性遺伝子の発現特徴の変性のための方法
CA2100329C (en) 1991-01-18 2009-09-29 David F. Carmichael Methods for treating tumor necrosis factor mediated diseases
IT1247484B (it) 1991-03-22 1994-12-17 Ceinge Societa Consortile A R Metodo per la preparazione di interleuchina 6
WO1994003492A1 (en) 1992-08-06 1994-02-17 The University Of Melbourne Interleukin-6 variants and uses therefor
IT1263022B (it) 1992-11-06 1996-07-23 Angeletti P Ist Richerche Bio Interleuchina-6 mutante con attivita' biologica migliorata rispetto all'interleuchina-6 selvatica.
IT1261787B (it) 1993-06-23 1996-06-03 Angeletti P Ist Richerche Bio Metodologia per la selezione di superagonisti, antagonisti e super- antagonisti di ormoni del cui complesso recettoriale fa parte gp 130.
US5635599A (en) 1994-04-08 1997-06-03 The United States Of America As Represented By The Department Of Health And Human Services Fusion proteins comprising circularly permuted ligands
WO1997016202A1 (en) * 1995-10-27 1997-05-09 Amrad Operations Pty. Ltd. Cytokines and their use in treatment and/or prophylaxis of breast cancer
JP4124486B2 (ja) * 1996-05-22 2008-07-23 ビベンティア バイオテック インコーポレイテッド ガン細胞を特異的に検出する抗原結合フラグメント、このフラグメントをコードするヌクレオチド、ならびにガンの予防および検出のためのその使用
WO1998036777A1 (en) * 1997-02-20 1998-08-27 Dime David S Site-specific drug delivery
IT1291932B1 (it) * 1997-06-20 1999-01-21 Angeletti P Ist Richerche Bio Composizioni farmaceutiche antitumorali capaci anche di ridurre la farmacoresistenza in cellule tumorali, in particolare di carcinoma
IL122818A0 (en) 1997-07-10 1998-08-16 Yeda Res & Dev Chimeric interleukin-6 soluble receptor/ligand protein analogs thereof and uses thereof
NZ517184A (en) 1999-07-13 2004-02-27 Bolder Biotechnology Inc Immunoglobulin fusion proteins that are cytokines or growth factors joined to an Immunoglobulin domain
BR0213183A (pt) * 2001-10-11 2004-08-31 Applied Research Systems Uso de ativadores gp130 em neuropatia diabética
IL163856A0 (en) 2004-09-01 2005-12-18 Applied Research Systems Use of IL-6 in vascular complications

Also Published As

Publication number Publication date
IL178636A0 (en) 2007-02-11
EP3124040A1 (en) 2017-02-01
EP1740200B1 (en) 2017-11-22
WO2005105135A8 (en) 2006-12-07
WO2005105135A1 (en) 2005-11-10
NO20065471L (no) 2007-01-09
CA2564390A1 (en) 2005-11-10
IL161673A0 (en) 2004-09-27
US20080193409A1 (en) 2008-08-14
PL1740200T3 (pl) 2018-04-30
US7951359B2 (en) 2011-05-31
PL3124040T3 (pl) 2020-08-24
ES2657049T3 (es) 2018-03-01
EP3124040B1 (en) 2020-02-12
EP1740200A1 (en) 2007-01-10
ES2788131T3 (es) 2020-10-20
JP2007534746A (ja) 2007-11-29
AU2005237324A1 (en) 2005-11-10
DK1740200T3 (da) 2018-01-08

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DK3124040T3 (da) Il-6 til terapi af kemoterapi-induceret neuropati
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