DK3110975T3 - Fremgangsmåder til analyse af somatiske mobile elementer og anvendelser deraf - Google Patents

Fremgangsmåder til analyse af somatiske mobile elementer og anvendelser deraf Download PDF

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DK3110975T3
DK3110975T3 DK15754498.2T DK15754498T DK3110975T3 DK 3110975 T3 DK3110975 T3 DK 3110975T3 DK 15754498 T DK15754498 T DK 15754498T DK 3110975 T3 DK3110975 T3 DK 3110975T3
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somatic
analysis
methods
mobile elements
mobile
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DK15754498.2T
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Danish (da)
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Keith Brown
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Jumpcode Genomics Inc
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
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    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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    • A61K49/001—Preparation for luminescence or biological staining
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DK15754498.2T 2014-02-27 2015-02-27 Fremgangsmåder til analyse af somatiske mobile elementer og anvendelser deraf DK3110975T3 (da)

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US201461945791P 2014-02-27 2014-02-27
PCT/US2015/018115 WO2015131110A1 (en) 2014-02-27 2015-02-27 Methods for analysis of somatic mobile elements, and uses thereof

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JP (2) JP6996844B2 (enExample)
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AU (2) AU2015222802B2 (enExample)
CA (3) CA2940669C (enExample)
DK (1) DK3110975T3 (enExample)
ES (1) ES2894048T3 (enExample)
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Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2734621B1 (en) 2011-07-22 2019-09-04 President and Fellows of Harvard College Evaluation and improvement of nuclease cleavage specificity
US11591637B2 (en) 2012-08-14 2023-02-28 10X Genomics, Inc. Compositions and methods for sample processing
US10273541B2 (en) 2012-08-14 2019-04-30 10X Genomics, Inc. Methods and systems for processing polynucleotides
EP3901273A1 (en) 2012-08-14 2021-10-27 10X Genomics, Inc. Microcapsule compositions and methods
US10752949B2 (en) 2012-08-14 2020-08-25 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9951386B2 (en) 2014-06-26 2018-04-24 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10400280B2 (en) 2012-08-14 2019-09-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10221442B2 (en) 2012-08-14 2019-03-05 10X Genomics, Inc. Compositions and methods for sample processing
US10323279B2 (en) 2012-08-14 2019-06-18 10X Genomics, Inc. Methods and systems for processing polynucleotides
US9701998B2 (en) 2012-12-14 2017-07-11 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10533221B2 (en) 2012-12-14 2020-01-14 10X Genomics, Inc. Methods and systems for processing polynucleotides
WO2014093676A1 (en) 2012-12-14 2014-06-19 10X Technologies, Inc. Methods and systems for processing polynucleotides
DK2954065T3 (da) 2013-02-08 2021-09-06 10X Genomics Inc Opdeling og bearbejdning af analytter og andre arter
JP6618894B2 (ja) 2013-05-23 2019-12-11 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 個別的エピゲノミクスのための天然クロマチンへの転移
US20180113137A1 (en) * 2013-10-18 2018-04-26 Tcm Biotech International Corp. Method for detecting the quantity of biomarker and identifying disease status
PL3102722T3 (pl) 2014-02-04 2021-03-08 Jumpcode Genomics, Inc. Frakcjonowanie genomu
BR112016023625A2 (pt) 2014-04-10 2018-06-26 10X Genomics, Inc. dispositivos fluídicos, sistemas e métodos para encapsular e particionar reagentes, e aplicações dos mesmos
AU2015279548B2 (en) 2014-06-26 2020-02-27 10X Genomics, Inc. Methods of analyzing nucleic acids from individual cells or cell populations
US12312640B2 (en) 2014-06-26 2025-05-27 10X Genomics, Inc. Analysis of nucleic acid sequences
MX2016016904A (es) 2014-06-26 2017-03-27 10X Genomics Inc Analisis de secuencias de acidos nucleicos.
JP2017532042A (ja) 2014-10-29 2017-11-02 １０エックス ゲノミクス，インコーポレイテッド 標的化核酸配列決定のための方法及び組成物
US9975122B2 (en) 2014-11-05 2018-05-22 10X Genomics, Inc. Instrument systems for integrated sample processing
SG11201705615UA (en) 2015-01-12 2017-08-30 10X Genomics Inc Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
CN115651972A (zh) 2015-02-24 2023-01-31 10X 基因组学有限公司 用于靶向核酸序列覆盖的方法
US10697000B2 (en) 2015-02-24 2020-06-30 10X Genomics, Inc. Partition processing methods and systems
EP3262175A4 (en) 2015-02-25 2018-10-31 Jumpcode Genomics, Inc. Methods and compositions for in silico long read sequencing
EP3384048B1 (en) 2015-12-04 2021-03-24 10X Genomics, Inc. Methods and compositions for nucleic acid analysis
US11339427B2 (en) 2016-02-12 2022-05-24 Jumpcode Genomics, Inc. Method for target specific RNA transcription of DNA sequences
WO2017197343A2 (en) 2016-05-12 2017-11-16 10X Genomics, Inc. Microfluidic on-chip filters
WO2017197338A1 (en) 2016-05-13 2017-11-16 10X Genomics, Inc. Microfluidic systems and methods of use
CN105886645A (zh) * 2016-05-27 2016-08-24 福建爱我健康生物科技有限公司 一种用于评估皮肤抗皱情况的引物和探针及试剂盒
US10815525B2 (en) 2016-12-22 2020-10-27 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10550429B2 (en) 2016-12-22 2020-02-04 10X Genomics, Inc. Methods and systems for processing polynucleotides
US10011872B1 (en) 2016-12-22 2018-07-03 10X Genomics, Inc. Methods and systems for processing polynucleotides
US12264411B2 (en) 2017-01-30 2025-04-01 10X Genomics, Inc. Methods and systems for analysis
EP4310183B1 (en) 2017-01-30 2025-07-09 10X Genomics, Inc. Methods and systems for droplet-based single cell barcoding
CN109526228B (zh) 2017-05-26 2022-11-25 10X基因组学有限公司 转座酶可接近性染色质的单细胞分析
US10844372B2 (en) 2017-05-26 2020-11-24 10X Genomics, Inc. Single cell analysis of transposase accessible chromatin
CN107245529A (zh) * 2017-08-08 2017-10-13 杭州千麦医学检验所有限公司 血液病融合基因筛查方法
SG11201913654QA (en) 2017-11-15 2020-01-30 10X Genomics Inc Functionalized gel beads
US10829815B2 (en) 2017-11-17 2020-11-10 10X Genomics, Inc. Methods and systems for associating physical and genetic properties of biological particles
EA202091673A1 (ru) 2018-01-29 2021-02-03 Ст. Джуд Чилдрен'С Рисерч Хоспитал, Инк. Способ амплификации нуклеиновых кислот
WO2019152108A1 (en) 2018-02-05 2019-08-08 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for multiplexed measurements in single and ensemble cells
CN108384846B (zh) * 2018-02-28 2020-06-16 固安博健生物技术有限公司 C11orf95基因及其表达产物在诊治类风湿性关节炎和骨关节炎方面的应用
CN112262218B (zh) 2018-04-06 2024-11-08 10X基因组学有限公司 用于单细胞处理中的质量控制的系统和方法
CN108588050B (zh) * 2018-05-14 2021-06-25 北京艾克伦医疗科技有限公司 Dna聚合酶以及核酸检测方法和试剂盒
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
KR102102107B1 (ko) * 2019-05-30 2020-04-20 단국대학교 천안캠퍼스 산학협력단 이동성 유전인자 SINE 선택적 발굴을 위한 HiSeq 시퀀서 기반의 DNA 라이브러리 제작 방법
CA3146298A1 (en) * 2019-07-30 2021-02-04 University Health Network T cell receptors and methods of use thereof
US20220290253A1 (en) * 2019-08-30 2022-09-15 Foundation Medicine, Inc. Kmt2a-maml2 fusion molecules and uses thereof
US20250230430A1 (en) * 2022-03-24 2025-07-17 Nanjing Legend Biotech Co., Ltd. Methods for preparing dna libraries and detecting retroviral integration sites

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9596098A (en) * 1997-09-29 1999-04-23 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Display technique for identifying line-1 insertion site polymorphisms
WO2000060113A2 (en) * 1999-04-01 2000-10-12 Mcgill University Transposon-based genetic marker
MXPA02002507A (es) * 1999-09-07 2004-09-10 Decode Genetics Ehf Deteccion de alteraciones en un gen por pcr de largo alcance mediante el uso de elementos moviles humanos.
US20050238658A1 (en) * 2002-03-05 2005-10-27 Maskell Duncan J Transposon
US20060035245A1 (en) * 2004-04-20 2006-02-16 Ason Brandon L Modulators of enzymatic nucleic acid elements mobilization
CN101310024B (zh) * 2005-11-14 2012-10-03 科因股份有限公司 高通量筛选转座子标记群体和大量平行的插入位点的序列鉴定方法
CA2685376A1 (en) * 2007-04-25 2008-11-06 John Wayne Cancer Institute Use of methylated or unmethylated line-1 dna as a cancer marker
US20120252015A1 (en) * 2011-02-18 2012-10-04 Bio-Rad Laboratories Methods and compositions for detecting genetic material
CN103952288A (zh) * 2009-04-02 2014-07-30 弗卢伊蒂格姆公司 用于对目标核酸进行条形码化的多引物扩增方法
US9028561B2 (en) * 2009-05-05 2015-05-12 Milliken & Company Bluing composition and method for treating textile articles using the same
US20130315886A1 (en) * 2009-08-05 2013-11-28 Salk Institute For Biological Studies Retroelements and mental disorders and methods of measuring l1 retrotransposition
WO2012048113A2 (en) * 2010-10-07 2012-04-12 The General Hospital Corporation Biomarkers of cancer

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EP3110975B1 (en) 2021-07-07
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CA2940669C (en) 2023-10-03
US20160376663A1 (en) 2016-12-29
EP3110975A4 (en) 2017-12-06
AU2015222802B2 (en) 2021-07-01
CA2940669A1 (en) 2015-09-03
CA3212153A1 (en) 2025-07-07
AU2015222802A1 (en) 2016-10-13
AU2021240134B2 (en) 2024-08-29
EP3943615A1 (en) 2022-01-26
US20230193401A1 (en) 2023-06-22
CN106414770A (zh) 2017-02-15
JP6996844B2 (ja) 2022-02-03
CN114250301A (zh) 2022-03-29
ES2894048T3 (es) 2022-02-11
JP2017512491A (ja) 2017-05-25
AU2021240134A1 (en) 2021-10-28
PL3110975T3 (pl) 2021-12-13
CA3214905A1 (en) 2015-09-03
WO2015131110A1 (en) 2015-09-03

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