DK3092243T3 - Organotinreagenser båret af ionisk væske til fremstilling af radiofarmaceutiske forbindelser - Google Patents
Organotinreagenser båret af ionisk væske til fremstilling af radiofarmaceutiske forbindelser Download PDFInfo
- Publication number
- DK3092243T3 DK3092243T3 DK15700962.2T DK15700962T DK3092243T3 DK 3092243 T3 DK3092243 T3 DK 3092243T3 DK 15700962 T DK15700962 T DK 15700962T DK 3092243 T3 DK3092243 T3 DK 3092243T3
- Authority
- DK
- Denmark
- Prior art keywords
- organotine
- preparation
- carried out
- ionic liquid
- pharmaceutical compounds
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000002608 ionic liquid Substances 0.000 title 1
- 239000012217 radiopharmaceutical Substances 0.000 title 1
- 229940121896 radiopharmaceutical Drugs 0.000 title 1
- 230000002799 radiopharmaceutical effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0006—Controlling or regulating processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/24—Stationary reactors without moving elements inside
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/78—Benzoic acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/24—Stationary reactors without moving elements inside
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14150296.3A EP2891657A1 (en) | 2014-01-07 | 2014-01-07 | Ionic liquid supported organotin reagents for the manufacturing of radiopharmaceuticals compounds |
| PCT/EP2015/050180 WO2015104300A1 (en) | 2014-01-07 | 2015-01-07 | Ionic liquid supported organotin reagents for the manufacturing of radiopharmaceuticals compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3092243T3 true DK3092243T3 (da) | 2019-09-30 |
Family
ID=49883036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15700962.2T DK3092243T3 (da) | 2014-01-07 | 2015-01-07 | Organotinreagenser båret af ionisk væske til fremstilling af radiofarmaceutiske forbindelser |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9714261B2 (da) |
| EP (2) | EP2891657A1 (da) |
| JP (1) | JP6639411B2 (da) |
| CA (1) | CA2936034A1 (da) |
| DK (1) | DK3092243T3 (da) |
| ES (1) | ES2746255T3 (da) |
| PL (1) | PL3092243T3 (da) |
| WO (1) | WO2015104300A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112430243B (zh) * | 2019-08-24 | 2023-03-21 | 江西师范大学 | 一种制备硫酯类化合物的方法 |
| US20230087487A1 (en) * | 2019-12-09 | 2023-03-23 | Cage Bio, Inc. | Topical delivery of rna interference agents using ionic liquid |
| EP4108648A4 (en) * | 2020-02-21 | 2024-01-24 | Univ Hokkaido Nat Univ Corp | METHOD FOR PRODUCING AN AROMATIC ASTATIN COMPOUND |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5510522A (en) | 1995-02-22 | 1996-04-23 | Regents Of The University Of California | Synthesis of N-formyl-3,4-di-t-butoxycarbonyloxy-6-(trimethylstannyl)-L-phenylalanine ethyl ester and its regioselective radiofluorodestannylation to 6- 18 F!fluoro-1-dopa |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| CA2345710C (en) | 1997-10-02 | 2008-12-30 | The University Of Western Ontario | Preparation of radiolabelled haloaromatics via polymer-bound intermediates |
| DE19928911B4 (de) | 1999-06-24 | 2006-06-29 | Forschungszentrum Rossendorf E.V. | Verfahren zur Herstellung von 3-0-Methyl-6-[18F]Fluor-DOPA, (3-0-Methyl-6-[18F]Fluor-L-4-hydroxyphenylalanin, 3-(2-[18F]Fluor-4-hydroxy-5-methoxy-phenyl)-2-amino-propansäure) |
| DE19949237B4 (de) | 1999-10-13 | 2004-07-29 | Abx Advanced Biochemical Compounds Biomedizinische Forschungsreagenzien Gmbh | Vorstufenverbindung für Radiodiagnostika und Verfahren zu ihrer Herstellung |
| WO2010059943A2 (en) | 2008-11-20 | 2010-05-27 | President And Fellows Of Harvard College | Fluorination of organic compounds |
-
2014
- 2014-01-07 EP EP14150296.3A patent/EP2891657A1/en not_active Withdrawn
-
2015
- 2015-01-07 ES ES15700962T patent/ES2746255T3/es active Active
- 2015-01-07 EP EP15700962.2A patent/EP3092243B1/en active Active
- 2015-01-07 US US15/109,856 patent/US9714261B2/en active Active
- 2015-01-07 JP JP2016562070A patent/JP6639411B2/ja not_active Expired - Fee Related
- 2015-01-07 DK DK15700962.2T patent/DK3092243T3/da active
- 2015-01-07 WO PCT/EP2015/050180 patent/WO2015104300A1/en active Application Filing
- 2015-01-07 CA CA2936034A patent/CA2936034A1/en not_active Abandoned
- 2015-01-07 PL PL15700962T patent/PL3092243T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2891657A1 (en) | 2015-07-08 |
| PL3092243T3 (pl) | 2020-02-28 |
| EP3092243B1 (en) | 2019-06-19 |
| US9714261B2 (en) | 2017-07-25 |
| JP2017504658A (ja) | 2017-02-09 |
| JP6639411B2 (ja) | 2020-02-05 |
| CA2936034A1 (en) | 2015-07-16 |
| ES2746255T3 (es) | 2020-03-05 |
| WO2015104300A1 (en) | 2015-07-16 |
| EP3092243A1 (en) | 2016-11-16 |
| US20160326194A1 (en) | 2016-11-10 |
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