DK299087D0 - PROTEINS AND DERIVATIVES THEREOF - Google Patents

PROTEINS AND DERIVATIVES THEREOF

Info

Publication number
DK299087D0
DK299087D0 DK299087A DK299087A DK299087D0 DK 299087 D0 DK299087 D0 DK 299087D0 DK 299087 A DK299087 A DK 299087A DK 299087 A DK299087 A DK 299087A DK 299087 D0 DK299087 D0 DK 299087D0
Authority
DK
Denmark
Prior art keywords
proteins
derivatives
Prior art date
Application number
DK299087A
Other languages
Danish (da)
Inventor
Bjoern Andersen Nexoe
Esper Boel
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK299087A priority Critical patent/DK299087D0/en
Publication of DK299087D0 publication Critical patent/DK299087D0/en
Priority to JP63505229A priority patent/JPH03503757A/en
Priority to EP88905725A priority patent/EP0365568A1/en
Priority to PCT/DK1988/000089 priority patent/WO1988009811A1/en
Priority to DK627389A priority patent/DK162169C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK299087A 1987-06-12 1987-06-12 PROTEINS AND DERIVATIVES THEREOF DK299087D0 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DK299087A DK299087D0 (en) 1987-06-12 1987-06-12 PROTEINS AND DERIVATIVES THEREOF
JP63505229A JPH03503757A (en) 1987-06-12 1988-06-09 Proteins and their derivatives
EP88905725A EP0365568A1 (en) 1987-06-12 1988-06-09 Proteins and derivatives thereof
PCT/DK1988/000089 WO1988009811A1 (en) 1987-06-12 1988-06-09 Proteins and derivatives thereof
DK627389A DK162169C (en) 1987-06-12 1989-12-12 RECOMBINATE PROTEINS WITH THROMBOMODULIN ACTIVITY, DNA CONSTRUCTIONS CODING THEREOF, VECTORS, CELLS AND PROCEDURES FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THE PROTEINES AND THE PROTEINES CONTAINING THE PROTEINES AND THE PROTEINES CONTAINING THE PROTEINES AND THE PROTEINES CONTAINING THE PROTEINS, AND THE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK299087A DK299087D0 (en) 1987-06-12 1987-06-12 PROTEINS AND DERIVATIVES THEREOF

Publications (1)

Publication Number Publication Date
DK299087D0 true DK299087D0 (en) 1987-06-12

Family

ID=8117912

Family Applications (1)

Application Number Title Priority Date Filing Date
DK299087A DK299087D0 (en) 1987-06-12 1987-06-12 PROTEINS AND DERIVATIVES THEREOF

Country Status (4)

Country Link
EP (1) EP0365568A1 (en)
JP (1) JPH03503757A (en)
DK (1) DK299087D0 (en)
WO (1) WO1988009811A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2766473B2 (en) * 1987-01-08 1998-06-18 旭化成工業株式会社 Peptide promoting the activation of protein C by thrombin
US4912207A (en) * 1987-05-06 1990-03-27 Washington University DNA clone of human thrombomodulin and portions thereof
EP0458903A4 (en) * 1989-02-17 1992-06-17 Codon Soluble analogs of thrombomodulin
US6063763A (en) * 1989-04-28 2000-05-16 Schering Aktiengesellschaft Protease-resistant thrombomodulin analogs
US6239101B1 (en) 1989-07-05 2001-05-29 Oklahoma Medical Research Foundation Thrombin binding polypeptides
CA2022713A1 (en) * 1989-08-11 1991-02-12 Nils U. Bang Human thrombomodulin derivatives
EP0489180A4 (en) * 1990-06-27 1993-03-31 Mochida Pharmaceutical Co., Ltd. Anticoagulant polypeptides
KR930008093B1 (en) * 1990-08-03 1993-08-25 아사히가세이고오교 가부시끼가이샤 New polypeptide and its composition
ES2170747T3 (en) * 1990-08-15 2002-08-16 Paion Gmbh SUPERIOR THROMBOMODULIN ANALOGS FOR PHARMACEUTICAL USE.
PT641215E (en) * 1992-02-05 2004-09-30 Paion Gmbh PROTEASE RESISTANT TROMBOMODULIN ANALOGS
ATE346928T1 (en) * 1994-10-18 2006-12-15 Dendreon Corp SERINE PROTEASE INHIBITORS AND COAGULATION-INHIBITING PROTEINS EXTRACTED FROM NEMATODES
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
JPH11299487A (en) * 1996-04-03 1999-11-02 Asahi Chem Ind Co Ltd New gene
MXPA04010795A (en) 2002-05-01 2005-03-07 Schering Ag Novel tissue factor targeted antibodies as anticoagulants.
US7579000B2 (en) 2002-05-01 2009-08-25 Bayer Schering Pharma Ag Tissue factor targeted antibodies as anticoagulants
WO2008044631A1 (en) 2006-10-06 2008-04-17 Asahi Kasei Pharma Corporation Therapeutic and/or ameliorating agent for disseminated intravascular coagulation
SG184699A1 (en) 2007-03-23 2012-10-30 Asahi Kasei Pharma Corp Method for producing high-purity soluble thrombomodulin
US20120165244A1 (en) * 2008-10-30 2012-06-28 Hua-Lin Wu Methods for binding lewis y antigen
EP2565269B1 (en) 2010-04-30 2016-11-16 Asahi Kasei Pharma Corporation Method for producing high-purity soluble thrombomodulin
KR20130099027A (en) * 2010-08-05 2013-09-05 카운슬 오브 사이언티픽 앤드 인더스트리얼 리서치 Protein fusion constructs possessing thrombolytic and anticoagulant properties
CN103974710B (en) 2011-11-15 2016-07-06 旭化成制药株式会社 Medicine for the treatment of septicemia and/or improvement
NZ702242A (en) 2012-05-31 2016-03-31 Asahi Kasei Pharma Corp Agent for prophylactic and/or therapeutic treatment of peripheral neuropathic pain caused by anticancer agent
JP7245844B2 (en) 2018-09-28 2023-03-24 旭化成ファーマ株式会社 Medicine for alleviating symptoms and/or suppressing the onset of peripheral neuropathy caused by antineoplastic agents
EP3871684B1 (en) 2018-10-22 2024-06-26 Asahi Kasei Pharma Corporation Drug for treating and/or improving septicemia associated with coagulation abnormality

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000050A1 (en) * 1985-06-28 1987-01-15 Asahi Kasei Kogyo Kabushiki Kaisha Novel physiologically active substance having blood coagulation controlling activity

Also Published As

Publication number Publication date
EP0365568A1 (en) 1990-05-02
WO1988009811A1 (en) 1988-12-15
JPH03503757A (en) 1991-08-22

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment