DK2968400T3 - Resorptionsfremmere som additiver til forbedring af den orale formulering af lavmolekylære hepariner - Google Patents
Resorptionsfremmere som additiver til forbedring af den orale formulering af lavmolekylære hepariner Download PDFInfo
- Publication number
- DK2968400T3 DK2968400T3 DK14774362.9T DK14774362T DK2968400T3 DK 2968400 T3 DK2968400 T3 DK 2968400T3 DK 14774362 T DK14774362 T DK 14774362T DK 2968400 T3 DK2968400 T3 DK 2968400T3
- Authority
- DK
- Denmark
- Prior art keywords
- heparines
- low molecular
- oral formulation
- improve oral
- additives
- Prior art date
Links
- 239000000654 additive Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Botany (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361778113P | 2013-03-12 | 2013-03-12 | |
| PCT/US2014/012360 WO2014158321A1 (en) | 2013-03-12 | 2014-01-21 | Resorption enhancers as additives to improve the oral formulation of low molecular weight heparins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2968400T3 true DK2968400T3 (da) | 2019-07-29 |
Family
ID=51527951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14774362.9T DK2968400T3 (da) | 2013-03-12 | 2014-01-21 | Resorptionsfremmere som additiver til forbedring af den orale formulering af lavmolekylære hepariner |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9265791B2 (enExample) |
| EP (2) | EP2968400B1 (enExample) |
| JP (2) | JP6377121B2 (enExample) |
| AU (1) | AU2014242354B2 (enExample) |
| DK (1) | DK2968400T3 (enExample) |
| ES (1) | ES2732659T3 (enExample) |
| WO (1) | WO2014158321A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111983207A (zh) * | 2019-05-23 | 2020-11-24 | 宁德市医院 | 一种血栓弹力图仪全血质控品及配制方法 |
| CN111658658B (zh) * | 2020-06-17 | 2023-08-11 | 上海大学 | 低聚木糖在制备抗深静脉血栓的药物中的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL79254A0 (en) | 1986-06-26 | 1986-09-30 | Hadassah Med Org | Compositions for preventing graft rejection |
| US5831005A (en) | 1992-09-24 | 1998-11-03 | Chiron Corporation | Synthesis of N-substituted oligomers |
| US5877278A (en) | 1992-09-24 | 1999-03-02 | Chiron Corporation | Synthesis of N-substituted oligomers |
| JP3714426B2 (ja) | 1994-02-01 | 2005-11-09 | 株式会社糖鎖工学研究所 | フコイダンオリゴ糖組成物含有癌転移抑制剤 |
| FR2754183A1 (fr) | 1996-10-08 | 1998-04-10 | Lefebvre Jean Marie | Composition visqueuse hemostatique, notamment a l'etat de gel |
| JP3371124B2 (ja) | 1996-12-24 | 2003-01-27 | 正邦 田幸 | 養殖オキナワモズクを原料とするアセチルフコイダンおよ びそれの製造法 |
| JP3580206B2 (ja) | 2000-02-01 | 2004-10-20 | 日本電気株式会社 | 携帯電話装置及び携帯電話装置の表示動作方法並びに携帯電話装置の表示動作プログラムを記録した記憶媒体 |
| JP4768142B2 (ja) | 2001-03-08 | 2011-09-07 | 協同乳業株式会社 | フコイダンの簡易製造方法 |
| CN1173997C (zh) | 2001-04-28 | 2004-11-03 | 武汉大学 | 高纯度魔芋葡甘聚糖的提取工艺 |
| CN1344565A (zh) | 2001-10-19 | 2002-04-17 | 汤洁 | 岩藻多糖酯作为抗病毒及免疫调节剂及其制备方法 |
| US20050282775A1 (en) | 2004-06-16 | 2005-12-22 | Paringenix, Inc. | Method and medicament for sulfated polysaccharide treatment of inflammation without inducing platelet activation and heparin-induced thrombocytopenia syndrome |
| US8114842B1 (en) | 2004-10-05 | 2012-02-14 | Gp Medical, Inc. | Nanoparticles for drug delivery |
| WO2008090631A1 (ja) | 2007-01-26 | 2008-07-31 | Suntory Holdings Limited | フコイダン由来オリゴ糖 |
| CA2838793C (en) | 2011-07-19 | 2019-08-06 | Baxter International Inc. | Resorption enhancers as additives to improve the oral formulation of non-anticoagulant sulfated polysaccharides |
-
2014
- 2014-01-21 EP EP14774362.9A patent/EP2968400B1/en active Active
- 2014-01-21 ES ES14774362T patent/ES2732659T3/es active Active
- 2014-01-21 WO PCT/US2014/012360 patent/WO2014158321A1/en not_active Ceased
- 2014-01-21 AU AU2014242354A patent/AU2014242354B2/en not_active Ceased
- 2014-01-21 US US14/160,235 patent/US9265791B2/en not_active Expired - Fee Related
- 2014-01-21 JP JP2016500174A patent/JP6377121B2/ja not_active Expired - Fee Related
- 2014-01-21 EP EP19173011.8A patent/EP3578184A1/en not_active Withdrawn
- 2014-01-21 DK DK14774362.9T patent/DK2968400T3/da active
-
2018
- 2018-07-24 JP JP2018138582A patent/JP2018184445A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2968400A1 (en) | 2016-01-20 |
| EP3578184A1 (en) | 2019-12-11 |
| US20140271608A1 (en) | 2014-09-18 |
| ES2732659T3 (es) | 2019-11-25 |
| US9265791B2 (en) | 2016-02-23 |
| JP2018184445A (ja) | 2018-11-22 |
| AU2014242354B2 (en) | 2016-07-07 |
| WO2014158321A1 (en) | 2014-10-02 |
| EP2968400B1 (en) | 2019-05-08 |
| EP2968400A4 (en) | 2016-08-10 |
| JP6377121B2 (ja) | 2018-08-22 |
| AU2014242354A1 (en) | 2015-04-02 |
| JP2016512244A (ja) | 2016-04-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3071203T3 (da) | Tetrahydroquinolinsammensætninger som bet-bromdomæne-inhibitorer | |
| DK3239134T3 (da) | Pyridonamider som modulatorer af natriumkanaler | |
| DK4275756T3 (da) | Bipyrazol-derivater som jak-hæmmere | |
| DK2968529T3 (da) | Fremstilling af jordnøddeformuleringer til oral desensibilisering | |
| DK3388834T3 (da) | Synergistisk forbedring af levering af nukleinsyrer via blandede formuleringer | |
| DK3363790T3 (da) | 1,2,4-oxadiazolderivater som immunmodulatorer | |
| DK3466949T3 (da) | Tricyklisk forbindelse som anticancermidler | |
| EP3068517A4 (en) | Compositions of lean nox trap | |
| EP3566740C0 (en) | FISTULAR FORMULATION/FORMATION DEVICES | |
| DK2845905T3 (da) | Fremstilling af oligosaccharider | |
| PL3578266T3 (pl) | Formulacja octanu abirateronu | |
| BR112016003454A2 (pt) | Uso de composto de metil bardoxolona | |
| DK2984166T3 (da) | Sammensætninger til behandling af mpsi | |
| DK2693881T3 (da) | Substituerede n-phenylpyrimidin-2-amin-analoger som inhibitorer af axl-kinase | |
| DK2961766T3 (da) | Kvantificering af vaccinesammensætninger | |
| EP2893918A4 (en) | ORAL COMPOSITION | |
| DK2981526T3 (da) | Naphthylureaderivater til anvendelse som kinaseinhibitorer | |
| DK3080052T3 (da) | Accelerationstilsætning til cementholdige sammensætninger | |
| DK3076983T4 (da) | Ioniske vandige sammensætninger | |
| DK3083617T3 (da) | Isochromene derivater som phosphoinositid 3-kinase-inhibitorer | |
| EP2958994A4 (en) | Vaccine composition | |
| DK2970442T3 (da) | Gla-domæner som terapeutiske midler | |
| DK3106150T3 (da) | Forbedrede farmaceutiske sammensætninger af pimobendan | |
| DK2822568T3 (da) | Anvendelser af caseinsammensætninger | |
| DK2965026T3 (da) | Generering af slushice |