DK295982A - Octahydro-4a,7-ethano- og -ethobenzofuro (3,2-e)isoquinolin-derivater samt fremgangsmaader til fremstilling heraf - Google Patents

Octahydro-4a,7-ethano- og -ethobenzofuro (3,2-e)isoquinolin-derivater samt fremgangsmaader til fremstilling heraf Download PDF

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Publication number
DK295982A
DK295982A DK295982A DK295982A DK295982A DK 295982 A DK295982 A DK 295982A DK 295982 A DK295982 A DK 295982A DK 295982 A DK295982 A DK 295982A DK 295982 A DK295982 A DK 295982A
Authority
DK
Denmark
Prior art keywords
ethobenzofuro
ethano
octahydro
procedures
preparing
Prior art date
Application number
DK295982A
Other languages
English (en)
Inventor
E Ciganek
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of DK295982A publication Critical patent/DK295982A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK295982A 1981-07-02 1982-07-01 Octahydro-4a,7-ethano- og -ethobenzofuro (3,2-e)isoquinolin-derivater samt fremgangsmaader til fremstilling heraf DK295982A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28013081A 1981-07-02 1981-07-02
US06/370,137 US4477456A (en) 1981-07-02 1982-04-22 Octahydro-4A,7-ethano- and -etheno-benzofuro[3,2-e]isoquinoline derivatives having analgesic, narcotic antagonist and anorexigenic properties

Publications (1)

Publication Number Publication Date
DK295982A true DK295982A (da) 1983-01-03

Family

ID=26960090

Family Applications (1)

Application Number Title Priority Date Filing Date
DK295982A DK295982A (da) 1981-07-02 1982-07-01 Octahydro-4a,7-ethano- og -ethobenzofuro (3,2-e)isoquinolin-derivater samt fremgangsmaader til fremstilling heraf

Country Status (4)

Country Link
US (1) US4477456A (da)
EP (2) EP0070427B1 (da)
DE (1) DE3275547D1 (da)
DK (1) DK295982A (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751306A (en) * 1985-09-09 1988-06-14 E. I. Du Pont De Nemours And Company Imide intermediates for the preparation of analgesic and/or antagonist octahydrobenzofuroisoquinolines
US4767764A (en) * 1986-05-27 1988-08-30 E. I. Du Pont De Nemours And Company Alkoxyalkyl and alkylmercaptoalkyl substituted bridged benzofuroisoquinolines having opioid antagonist and/or appetite-controlling properties
WO2016172613A1 (en) * 2015-04-23 2016-10-27 Trevi Therapeutics, Inc. Compounds for treating pruritic conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474101A (en) * 1960-09-05 1969-10-21 Reckitt & Sons Ltd Thebaine and oripavine derivatives
US3318884A (en) * 1965-07-21 1967-05-09 American Cyanamid Co Substituted 6-amino-6-demethoxythebaine and 6-amino-6-demethoxyoripavine derivatives
US3488354A (en) * 1967-09-27 1970-01-06 American Cyanamid Co Substituted 7,8 - dihydro - 6-hydroxy-6,14-endo (etheno or ethano)codide - 7-ketones and substituted 7,8 - dihydro-6-hydroxy-6,14-endo (etheno or ethano) morphide-7-ketones
DK337879A (da) * 1978-10-02 1980-04-03 Du Pont Fremgangsmaade til fremstilling af octahydro-1h-benzo(4,5)furo(3,2-e) isoquinoliner og mellemprodukter til brug herved
US4243668A (en) * 1979-07-09 1981-01-06 E. I. Du Pont De Nemours And Company Octahydro-1H-benzo[4,5]furo[3,2-e]-isoquinoline analgesic and narcotic antagonistic compounds

Also Published As

Publication number Publication date
US4477456A (en) 1984-10-16
EP0070427A2 (en) 1983-01-26
DE3275547D1 (en) 1987-04-09
EP0070427B1 (en) 1987-03-04
EP0070427A3 (en) 1983-04-06
EP0164136A1 (en) 1985-12-11

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Legal Events

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AHB Application shelved due to non-payment