DK295586A - Cyclopentanderivater - Google Patents
Cyclopentanderivater Download PDFInfo
- Publication number
- DK295586A DK295586A DK295586A DK295586A DK295586A DK 295586 A DK295586 A DK 295586A DK 295586 A DK295586 A DK 295586A DK 295586 A DK295586 A DK 295586A DK 295586 A DK295586 A DK 295586A
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- cyclopentan
- derivatives
- trifluoromethyl
- fluoro
- Prior art date
Links
- RGSFGYAAUTVSQA-UHFFFAOYSA-N Cyclopentane Chemical class C1CCCC1 RGSFGYAAUTVSQA-UHFFFAOYSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002744 anti-aggregatory effect Effects 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/747,740 US4634782A (en) | 1985-06-24 | 1985-06-24 | 7-fluoro-dihydro PGI compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK295586D0 DK295586D0 (da) | 1986-06-23 |
| DK295586A true DK295586A (da) | 1986-12-25 |
Family
ID=25006425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK295586A DK295586A (da) | 1985-06-24 | 1986-06-23 | Cyclopentanderivater |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4634782A (fr) |
| EP (1) | EP0209694B1 (fr) |
| JP (1) | JPS62482A (fr) |
| AT (1) | ATE45575T1 (fr) |
| AU (1) | AU595533B2 (fr) |
| DE (1) | DE3665063D1 (fr) |
| DK (1) | DK295586A (fr) |
| IL (1) | IL79168A0 (fr) |
| NZ (1) | NZ216613A (fr) |
| PH (1) | PH24217A (fr) |
| ZA (1) | ZA864590B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59227888A (ja) * | 1983-06-10 | 1984-12-21 | Asahi Glass Co Ltd | ７−フルオロプロスタグランジン類の製造方法 |
| CH674363A5 (fr) * | 1986-12-01 | 1990-05-31 | Hoffmann La Roche | |
| US4808734A (en) * | 1986-12-01 | 1989-02-28 | Hoffmann-La Roche Inc. | 16-cycloalkyl-7-fluoro-prostacyclins |
| DE69531110T2 (de) * | 1994-02-17 | 2004-05-19 | Asahi Glass Co., Ltd. | Difluoroprostacycline, Zwischenprodukte zu deren Herstellung und Herstellungsverfahren |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6570680A (en) * | 1979-10-10 | 1981-04-28 | University Of Chicago, The | Chemical synthesis |
| GB2088856B (en) * | 1980-10-27 | 1984-06-27 | Chinoin Gyogyszer Es Vegyeszet | 7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them |
| EP0054795B1 (fr) * | 1980-12-09 | 1987-07-15 | Teijin Limited | Prostacyclines halogénées, procédé pour leur préparation et leur utilisation en pharmacie |
| US4558142A (en) * | 1981-03-11 | 1985-12-10 | Hoffmann-La Roche Inc. | 7-Fluoro-prostacyclin analogs |
| CH648556A5 (de) * | 1981-03-11 | 1985-03-29 | Hoffmann La Roche | Fluorprostacycline. |
| JPS59227888A (ja) * | 1983-06-10 | 1984-12-21 | Asahi Glass Co Ltd | ７−フルオロプロスタグランジン類の製造方法 |
-
1985
- 1985-06-24 US US06/747,740 patent/US4634782A/en not_active Expired - Fee Related
-
1986
- 1986-06-06 EP EP86107750A patent/EP0209694B1/fr not_active Expired
- 1986-06-06 AT AT86107750T patent/ATE45575T1/de active
- 1986-06-06 DE DE8686107750T patent/DE3665063D1/de not_active Expired
- 1986-06-19 IL IL79168A patent/IL79168A0/xx unknown
- 1986-06-19 ZA ZA864590A patent/ZA864590B/xx unknown
- 1986-06-20 NZ NZ216613A patent/NZ216613A/xx unknown
- 1986-06-20 PH PH33921A patent/PH24217A/en unknown
- 1986-06-23 AU AU59204/86A patent/AU595533B2/en not_active Expired - Fee Related
- 1986-06-23 DK DK295586A patent/DK295586A/da not_active Application Discontinuation
- 1986-06-24 JP JP61147984A patent/JPS62482A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA864590B (en) | 1987-02-25 |
| DK295586D0 (da) | 1986-06-23 |
| PH24217A (en) | 1990-04-10 |
| IL79168A0 (en) | 1986-09-30 |
| DE3665063D1 (en) | 1989-09-21 |
| US4634782A (en) | 1987-01-06 |
| ATE45575T1 (de) | 1989-09-15 |
| JPS62482A (ja) | 1987-01-06 |
| NZ216613A (en) | 1989-04-26 |
| EP0209694B1 (fr) | 1989-08-16 |
| AU595533B2 (en) | 1990-04-05 |
| EP0209694A1 (fr) | 1987-01-28 |
| AU5920486A (en) | 1987-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |