DK2938999T3 - Prøvebearbejdningssystemer og fremgangsmåder til at holde objektglas - Google Patents
Prøvebearbejdningssystemer og fremgangsmåder til at holde objektglas Download PDFInfo
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- DK2938999T3 DK2938999T3 DK13824703.6T DK13824703T DK2938999T3 DK 2938999 T3 DK2938999 T3 DK 2938999T3 DK 13824703 T DK13824703 T DK 13824703T DK 2938999 T3 DK2938999 T3 DK 2938999T3
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
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- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Sampling And Sample Adjustment (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Microscoopes, Condenser (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Claims (13)
1. Automatisk objektglas-bearbejdningsapparat konfigureret til at påføre mindst et reagens til en prøve båret på et mikroskopobjektglas, hvilket automatisk objektglas-bearbejdningsapparat omfatter: et støtteelement (703) med en støtteflade og omfattende en rende (737); mindst en vakuumtilslutningsåbning (721); og et tætningselement (709), hvor tætningselementet (709) i en ikke-komprimeret tilstand strækker sig opad på den anden side af støttefladen og i en komprimeret tilstand er konfigureret til at opretholde en lufttæt afdækning med en bagside af mikroskopobjektglasset når mikroskopobjektglasset er trukket mod støttefladen af et vakuum trukket via den mindst ene vakuumtilslutningsåbning (721), kendetegnet ved at tætningselementet (709) har, som set langs en akse generelt vinkelret til støttefladen, en polygonal form eller en rundet-hjørne polygonal form, og at hvor tætningselementet (709) omfatter en føjelig pakning med et hovedlegeme (747) og en læbe (749), hvor hovedlegemet (747) er positioneret i renden (737), og hvor læben (749) strækker sig radialt udad fra hovedlegemet (747).
2. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor tætningselementet (709) har en rundet-hjørne rektangulær form eller en rektangulær form som set fra oven.
3. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor, når mikroskopobjektglasset er trukket mod støttefladen, læben (749) er konfigureret til at være adskilt fra en sidevæg (741) af renden (737) men i stand til fysisk at kontakte sidevæggen (741) af renden (737) for at forhindre bevægelse af mikroskopobjektglasset i forhold til støtteelementet (703).
4. Automatisk objektglas-bearbejdningsapparat ifølge krav 3, hvor læben (749) er konfigureret til fysisk at kontakte sidevæggen (741) når mikroskopobjektglasset er drejet mindst ca. 2 grader omkring en lodret akse omgivet af tætningselementet (709).
5. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor læben (749) i en ikke-komprimeret konfiguration strækker sig opad fra renden (737), hvor læben (749) i en komprimeret konfiguration strækker sig mod en sidevæg (741) af renden (737), og hvor læben (749) er bevægelig mellem den ikkekomprimerede konfiguration og den komprimerede konfiguration uden at kontakte sidevæggen (741) af renden (737).
6. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor tætningselementet (709) i en komprimeret konfiguration er positioneret på en side af et plan i hvilket en bagsideflade af mikroskopobjektglasset er anbragt når mikroskopobjektglasset er trukket mod støttefladen, og tætningselementet (709) i en ikke-komprimeret konfiguration er anbragt på begge sider af planet.
7. Automatisk objektglas-bearbejdningsapparat ifølge krav 6, hvor støtteelementet (703) omfatter en vakuumflade omgivet af den mindst ene vakuumtilslutningsåbning (721), hvor vakuumfladen er adskilt med mellemrum fra og positioneret under planet således af vakuumfladen og mikroskopobjektglasset mindst delvist definerer et vakuumkammer med en højde mindre end højden af tætningselementet (709).
8. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor tætningselementet (709) omfatter en læbe (749) konfigureret til at afbøje primært i en retning lodret til en bagsideflade af mikroskopobjektglasset under brug.
9. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor læben (749) er bevægelig mellem en ikke-komprimeret konfiguration for at kontakte objektglasset der bevæges mod støttefladen og en komprimeret konfiguration for at opretholde den lufttætte tætning, hvor læben (749) i den ikke-komprimerede position strækker sig opad på den anden side af overfladen, og hvor læben (749) i den komprimerede position er placeret ved eller under en overflade.
10. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor læben (749) er konfigureret til at blive afbøjet efterhånden som mikroskopobjektglasset bevæges mod støttefladen til at danne den lufttætte tætning.
11. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, hvor tætningselementet (709) er positioneret til at blive anbragt under en markør af mikroskopobjektglasset.
12. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, yderligere omfattende en vakuumkilde (717) i fluid kontakt med den mindst ene vakuumtilslutningsåbning (721) og konfigureret til at trække et tilstrækkeligt vakuum til at opretholde den lufttætte tætning.
13. Automatisk objektglas-bearbejdningsapparat ifølge krav 1, yderligere omfattende en varmegiver konfigureret til at opvarme støtteelementet (703) således at støtteelementet (703) ledende opvarmer mikroskopobjektglasset mens tætningselementet (709) opretholder den lufttætte tætning.
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| PCT/US2013/077177 WO2014105744A2 (en) | 2012-12-26 | 2013-12-20 | Specimen processing systems and methods for holding slides |
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| US10746752B2 (en) | 2009-11-13 | 2020-08-18 | Ventana Medical Systems, Inc. | Opposables and automated specimen processing systems with opposables |
| US11274998B2 (en) | 2012-12-26 | 2022-03-15 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for holding slides |
| US9989448B2 (en) | 2012-12-26 | 2018-06-05 | Ventana Medical Systems, Inc. | Specimen processing systems and methods for holding slides |
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| CN106370830A (zh) * | 2016-11-14 | 2017-02-01 | 漯河医学高等专科学校 | 一种具有单独滑片加热器的分子病理学装置 |
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| CN110186736B (zh) * | 2019-06-27 | 2021-11-23 | 宁波舜宇仪器有限公司 | 液基标本制片染色机的玻片夹 |
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