DK2935567T3 - Differentieret cellepopulation af endotelceller afledt af humane pluripotente stamceller, sammensætning, system, kit og anvendelser deraf - Google Patents
Differentieret cellepopulation af endotelceller afledt af humane pluripotente stamceller, sammensætning, system, kit og anvendelser deraf Download PDFInfo
- Publication number
- DK2935567T3 DK2935567T3 DK13826629.1T DK13826629T DK2935567T3 DK 2935567 T3 DK2935567 T3 DK 2935567T3 DK 13826629 T DK13826629 T DK 13826629T DK 2935567 T3 DK2935567 T3 DK 2935567T3
- Authority
- DK
- Denmark
- Prior art keywords
- endotel
- kit
- applications
- composition
- cell population
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/42—Notch; Delta; Jagged; Serrate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT10669912 | 2012-12-18 | ||
PCT/IB2013/061110 WO2014097192A2 (en) | 2012-12-18 | 2013-12-18 | Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition, system, kit and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2935567T3 true DK2935567T3 (da) | 2019-05-06 |
Family
ID=50030376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13826629.1T DK2935567T3 (da) | 2012-12-18 | 2013-12-18 | Differentieret cellepopulation af endotelceller afledt af humane pluripotente stamceller, sammensætning, system, kit og anvendelser deraf |
Country Status (6)
Country | Link |
---|---|
US (2) | US20150329822A1 (da) |
EP (1) | EP2935567B1 (da) |
DK (1) | DK2935567T3 (da) |
ES (1) | ES2731529T3 (da) |
PT (1) | PT2935567T (da) |
WO (1) | WO2014097192A2 (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112017017886B1 (pt) | 2015-02-20 | 2024-02-06 | Wisconsin Alumni Research Foundation | Método para obter células endoteliais arteriais humanas, populações isoladas puras de células endoteliais arteriais, método de rastreio de um agente in vitro, método in vitro para vascularizar um construto de tecido engenheirado, uso das referidas células e composição farmacêutica compreendendo as referidas células |
KR101998633B1 (ko) * | 2017-10-31 | 2019-07-11 | 가톨릭관동대학교산학협력단 | 엘립티신의 줄기세포의 연골세포로의 분화 유도 용도 |
EP3875124A1 (fr) | 2020-03-02 | 2021-09-08 | Urgo Recherche Innovation Et Developpement | Procede d'obtention d'un tissu dermo-epidermique pre-vascularise |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7071199B1 (en) | 1999-09-17 | 2006-07-04 | Abbott Gmbh & Cco. Kg | Kinase inhibitors as therapeutic agents |
EP2428563A1 (en) * | 2005-02-10 | 2012-03-14 | Regents Of The University Of Minnesota | Vascular/lymphatic endothelial cells |
JP5666134B2 (ja) * | 2007-01-10 | 2015-02-12 | ヘモシアー・リミテッド・ライアビリティ・カンパニーHemoShear, LLC | 血管疾患の新たな治療標的を同定するためのインビトロの血行力学的内皮/平滑筋細胞共培養モデルの使用 |
CN103635587A (zh) * | 2008-04-08 | 2014-03-12 | 麻省理工学院 | 三维微流平台和其使用方法 |
US20120301443A1 (en) * | 2009-12-29 | 2012-11-29 | Cornell University | Methods for developing endothelial cells from pluripotent cells and endothelial cells derived |
US20120211373A1 (en) * | 2011-02-22 | 2012-08-23 | The Regents Of The University Of Michigan | Microfluidic system for measuring cell barrier function |
WO2013075248A1 (en) * | 2011-11-23 | 2013-05-30 | The Governing Council Of The University Of Toronto | Devices and methods for producing planar polymeric materials using microfluidics |
-
2013
- 2013-12-18 ES ES13826629T patent/ES2731529T3/es active Active
- 2013-12-18 PT PT13826629T patent/PT2935567T/pt unknown
- 2013-12-18 EP EP13826629.1A patent/EP2935567B1/en active Active
- 2013-12-18 DK DK13826629.1T patent/DK2935567T3/da active
- 2013-12-18 US US14/651,548 patent/US20150329822A1/en not_active Abandoned
- 2013-12-18 WO PCT/IB2013/061110 patent/WO2014097192A2/en active Application Filing
-
2017
- 2017-06-29 US US15/637,068 patent/US10526580B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20180023051A1 (en) | 2018-01-25 |
PT2935567T (pt) | 2019-05-29 |
EP2935567A2 (en) | 2015-10-28 |
ES2731529T3 (es) | 2019-11-15 |
US10526580B2 (en) | 2020-01-07 |
EP2935567B1 (en) | 2019-01-30 |
WO2014097192A3 (en) | 2015-01-08 |
WO2014097192A2 (en) | 2014-06-26 |
US20150329822A1 (en) | 2015-11-19 |
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