DK2935567T3 - Differentieret cellepopulation af endotelceller afledt af humane pluripotente stamceller, sammensætning, system, kit og anvendelser deraf - Google Patents
Differentieret cellepopulation af endotelceller afledt af humane pluripotente stamceller, sammensætning, system, kit og anvendelser deraf Download PDFInfo
- Publication number
- DK2935567T3 DK2935567T3 DK13826629.1T DK13826629T DK2935567T3 DK 2935567 T3 DK2935567 T3 DK 2935567T3 DK 13826629 T DK13826629 T DK 13826629T DK 2935567 T3 DK2935567 T3 DK 2935567T3
- Authority
- DK
- Denmark
- Prior art keywords
- endotel
- kit
- applications
- composition
- cell population
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 title 2
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/42—Notch; Delta; Jagged; Serrate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Vascular Medicine (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT10669912 | 2012-12-18 | ||
PCT/IB2013/061110 WO2014097192A2 (en) | 2012-12-18 | 2013-12-18 | Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition, system, kit and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2935567T3 true DK2935567T3 (da) | 2019-05-06 |
Family
ID=50030376
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13826629.1T DK2935567T3 (da) | 2012-12-18 | 2013-12-18 | Differentieret cellepopulation af endotelceller afledt af humane pluripotente stamceller, sammensætning, system, kit og anvendelser deraf |
Country Status (6)
Country | Link |
---|---|
US (2) | US20150329822A1 (da) |
EP (1) | EP2935567B1 (da) |
DK (1) | DK2935567T3 (da) |
ES (1) | ES2731529T3 (da) |
PT (1) | PT2935567T (da) |
WO (1) | WO2014097192A2 (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016134313A1 (en) * | 2015-02-20 | 2016-08-25 | Wisconsin Alumni Research Foundation | Generating arterial endothelial cell populations |
KR101998633B1 (ko) * | 2017-10-31 | 2019-07-11 | 가톨릭관동대학교산학협력단 | 엘립티신의 줄기세포의 연골세포로의 분화 유도 용도 |
EP3875124A1 (fr) | 2020-03-02 | 2021-09-08 | Urgo Recherche Innovation Et Developpement | Procede d'obtention d'un tissu dermo-epidermique pre-vascularise |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7071199B1 (en) | 1999-09-17 | 2006-07-04 | Abbott Gmbh & Cco. Kg | Kinase inhibitors as therapeutic agents |
US20090104159A1 (en) * | 2005-02-10 | 2009-04-23 | Felipe Prosper | Vascular/Lymphatic Endothelial Cells |
EP2118268B1 (en) * | 2007-01-10 | 2015-07-08 | Hemoshear, LLC | Use of an in vitro hemodynamic endothelial/smooth muscle cell co-culture model to identify new therapeutic targets for vascular disease |
CN103635587A (zh) * | 2008-04-08 | 2014-03-12 | 麻省理工学院 | 三维微流平台和其使用方法 |
US20120301443A1 (en) * | 2009-12-29 | 2012-11-29 | Cornell University | Methods for developing endothelial cells from pluripotent cells and endothelial cells derived |
US20120211373A1 (en) * | 2011-02-22 | 2012-08-23 | The Regents Of The University Of Michigan | Microfluidic system for measuring cell barrier function |
CA2856063A1 (en) * | 2011-11-23 | 2013-05-30 | The Governing Council Of The University Of Toronto | Devices and methods for producing planar polymeric materials using microfluidics |
-
2013
- 2013-12-18 ES ES13826629T patent/ES2731529T3/es active Active
- 2013-12-18 EP EP13826629.1A patent/EP2935567B1/en active Active
- 2013-12-18 US US14/651,548 patent/US20150329822A1/en not_active Abandoned
- 2013-12-18 WO PCT/IB2013/061110 patent/WO2014097192A2/en active Application Filing
- 2013-12-18 DK DK13826629.1T patent/DK2935567T3/da active
- 2013-12-18 PT PT13826629T patent/PT2935567T/pt unknown
-
2017
- 2017-06-29 US US15/637,068 patent/US10526580B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20150329822A1 (en) | 2015-11-19 |
US10526580B2 (en) | 2020-01-07 |
EP2935567A2 (en) | 2015-10-28 |
WO2014097192A2 (en) | 2014-06-26 |
WO2014097192A3 (en) | 2015-01-08 |
PT2935567T (pt) | 2019-05-29 |
US20180023051A1 (en) | 2018-01-25 |
EP2935567B1 (en) | 2019-01-30 |
ES2731529T3 (es) | 2019-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK2577318T3 (da) | Fremgangsmåde til nociceptor-differentiering af humane embryoniske stamceller og anvendelser deraf | |
IL240881A0 (en) | Expression of the t cell balance gene, preparations, materials and methods for its use | |
DK2938722T3 (da) | Suspension og klyngedannelse af humane pluripotente celler til differentiering til endokrine pankreasceller | |
DK2780022T3 (da) | Farmaceutiske præparater af humane rpe-celler og anvendelser deraf | |
DK2855667T3 (da) | Fremgangsmåder til manipulation af allogeniske og immunosuppressiv-resistante T-celler til immunterapi | |
DK2838548T5 (en) | Hla class ii deficient cells, hla class i deficient cells capable of expressing hla class ii proteins, and uses thereof | |
EP2811011A4 (en) | CELL CULTURE KIT AND METHOD FOR USING THE CELL CULTURE KIT | |
DK2705143T3 (da) | Protein-induceret pluripotent celleteknologi og anvendelse deraf | |
IL241294A0 (en) | Genetic expression of response in dendritic cells, preparations and methods of use | |
HK1207114A1 (en) | Compositions and methods of obtaining and using endoderm and hepatocyte cells | |
DK3064585T3 (da) | Konstruering og optimering af forbedrede systemer, fremgangsmåder og enzymsammensætninger til sekvensmanipulation | |
BR112012033538A2 (pt) | linhagem celular imortalizada e método de replicação de um vírus | |
DK3450542T3 (da) | Differentiering af humane embryonale stamceller til endokrine pancreatiske celler | |
DK2638149T3 (da) | Immortalisering af epitelceller og fremgangsmåder til anvendelse | |
DK2614141T3 (da) | Hidtil ukendte fremgangsmåder og dyrkningsmedier til dyrkning af pluripotente stamceller | |
DK2686421T3 (da) | Generering af nk-celler og nk-celleforløbere | |
DK2893001T3 (da) | Fremgangsmåde til dyrkning af mesenkymale stamceller | |
DK3039122T3 (da) | Generering af endokrine progenitorceller fra humane pluripotente stamceller under anvendelse af små molekyler | |
DK3546569T3 (da) | Terapeutiske midler med anvendelse af fedtceller og cellesekreter | |
DK2934093T3 (da) | Stabil transformation af en population og fremgangsmåde til biocontainment under anvendelse af haploinsufficiens- og underdominansprincipper | |
DK2647068T3 (da) | Batterielektrode og metode til fremstilling af samme | |
BR112014022817A2 (pt) | Processo de aumento da criopreservação de células biológicas e composição de criopreservação | |
DK2817406T3 (da) | Engangsseparator til tilbageholdelse og tilbageføring af celler | |
EP2612911A4 (en) | COMPOSITION FOR THE INDUCTION OF PLURIPOTENTER STEM CELLS AND THEIR USE | |
DK2658965T3 (da) | Fremgangsmåde til fremstilling af inducerede pluripotente stamceller og differentierede celler |