DK2909229T3 - Hitherto UNKNOWN RECOMBINANT TABLE TELLS - Google Patents
Hitherto UNKNOWN RECOMBINANT TABLE TELLS Download PDFInfo
- Publication number
- DK2909229T3 DK2909229T3 DK13777082.2T DK13777082T DK2909229T3 DK 2909229 T3 DK2909229 T3 DK 2909229T3 DK 13777082 T DK13777082 T DK 13777082T DK 2909229 T3 DK2909229 T3 DK 2909229T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- fha
- gene
- strain
- bordetella pertussis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12306279.6A EP2722338A1 (en) | 2012-10-17 | 2012-10-17 | Novel recombinant Bordetella strains |
| PCT/EP2013/071724 WO2014060514A1 (en) | 2012-10-17 | 2013-10-17 | Novel recombinant bordetella strains |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2909229T3 true DK2909229T3 (en) | 2019-03-25 |
Family
ID=47073385
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13777082.2T DK2909229T3 (en) | 2012-10-17 | 2013-10-17 | Hitherto UNKNOWN RECOMBINANT TABLE TELLS |
| DK18194351.5T DK3459966T3 (da) | 2012-10-17 | 2013-10-17 | Ny recombinant bordetella strain |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18194351.5T DK3459966T3 (da) | 2012-10-17 | 2013-10-17 | Ny recombinant bordetella strain |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9528086B2 (enExample) |
| EP (3) | EP2722338A1 (enExample) |
| JP (3) | JP6473086B2 (enExample) |
| CN (2) | CN110923181A (enExample) |
| AU (1) | AU2013333928B2 (enExample) |
| CA (1) | CA2887055C (enExample) |
| DK (2) | DK2909229T3 (enExample) |
| ES (2) | ES2715651T3 (enExample) |
| SG (2) | SG10201706392YA (enExample) |
| WO (1) | WO2014060514A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007104451A1 (en) | 2006-03-10 | 2007-09-20 | Institut Pasteur De Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| CN102448490B (zh) | 2009-04-28 | 2015-05-13 | 国家健康与医学研究院 | 用于预防或治疗过敏原引起的气道疾病的疫苗 |
| SG10201607233TA (en) | 2011-11-02 | 2016-10-28 | Univ Singapore | Effect of an attenuated bordetella strain against allergic disease |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| KR101672719B1 (ko) * | 2014-07-22 | 2016-11-04 | 전남대학교산학협력단 | 바이러스 중화항원 단백질 발현을 위한 보르데텔라 백일해 균주 및 이를 이용한 면역원성 조성물 |
| US9655959B2 (en) | 2014-10-01 | 2017-05-23 | National University Of Singapore | Adenylate cyclase deficient bordetella strains |
| EP3283102A4 (en) * | 2015-04-16 | 2018-10-03 | Inventprise, LLC. | Bordetella pertussis immunogenic vaccine compositions |
| US10682377B2 (en) | 2016-03-29 | 2020-06-16 | Institut Pasteur De Lille | Mutant Bordetella strains and methods of use |
| EP3697439A1 (en) | 2017-10-18 | 2020-08-26 | Institut Pasteur de Lille | Bordetella strains expressing serotype 3 fimbriae |
| BR112021013241A2 (pt) * | 2019-01-04 | 2021-09-14 | Boehringer Ingelheim Animal Health USA Inc. | Cepas atenuadas de bordetella bronchiseptica, vacinas orais contendo as cepas atenuadas e métodos de preparação e uso das mesmas |
| AU2021325149A1 (en) | 2020-08-14 | 2023-03-02 | ILiAD Biotechnologies, Inc. | Lyophilized live bordetella vaccines |
| EP3909971A1 (en) | 2020-09-28 | 2021-11-17 | Institute of Life Sciences (ILS) | Whole cell livestock vaccine for respiratory diseases |
| CN116635517A (zh) * | 2020-11-17 | 2023-08-22 | 伊利亚德生物技术有限公司 | 与神经退行性疾病相关的神经病理的治疗和预防 |
| CN113429188B (zh) * | 2021-06-18 | 2022-06-10 | 湖北沛高环保科技有限公司 | 一种尾矿固废综合处理利用方法 |
| CN116265584A (zh) * | 2021-12-17 | 2023-06-20 | 远大赛威信生命科学(南京)有限公司 | 百日咳抗原重组表达载体及其工程菌和应用 |
| WO2025257397A1 (en) * | 2024-06-14 | 2025-12-18 | Institut National de la Santé et de la Recherche Médicale | Live attenuated bordetella vaccines capable of producing and secreting heterologous antigens |
| CN118853525B (zh) * | 2024-09-26 | 2025-01-07 | 上海羽冠生物技术有限公司 | 经修饰的百日咳鲍特菌菌株 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6713072B1 (en) | 1987-11-02 | 2004-03-30 | Chiron S.R.L. | Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine |
| GB9115332D0 (en) * | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
| FR2718750B1 (fr) | 1994-04-19 | 1996-06-14 | Pasteur Institut | Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants. |
| FR2728170A1 (fr) * | 1994-12-15 | 1996-06-21 | Pasteur Institut | Vaccin de type acellulaire anti-bordetella |
| FR2754543B1 (fr) | 1996-10-11 | 1998-12-31 | Pasteur Institut | Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires |
| FR2840319B1 (fr) | 2002-05-30 | 2004-08-20 | Pasteur Institut | Souches de bordetella rendues deficientes par attenuation genetique |
| US7582297B2 (en) | 2003-04-11 | 2009-09-01 | Medimmune, Llc | Methods of treating respiratory conditions |
| WO2007104451A1 (en) | 2006-03-10 | 2007-09-20 | Institut Pasteur De Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| US20100111996A1 (en) | 2006-11-15 | 2010-05-06 | Denis Leclerc | Papaya Mosaic Virus-Based Vaccines for Influenza |
| AU2008266910A1 (en) | 2007-06-18 | 2008-12-24 | Hemispherx Biopharma, Inc. | Early intervention of viral infections with immune activators |
| JP2011116659A (ja) * | 2008-03-13 | 2011-06-16 | Chemo-Sero-Therapeutic Research Inst | 組換え皮膚壊死トキソイドを含有する豚萎縮性鼻炎用薬剤 |
| CN102448490B (zh) | 2009-04-28 | 2015-05-13 | 国家健康与医学研究院 | 用于预防或治疗过敏原引起的气道疾病的疫苗 |
| CA2765364C (en) | 2009-06-15 | 2015-05-26 | National University Of Singapore | Influenza vaccine, composition, and methods of use |
| SG10201607233TA (en) | 2011-11-02 | 2016-10-28 | Univ Singapore | Effect of an attenuated bordetella strain against allergic disease |
| EP2722338A1 (en) | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
-
2012
- 2012-10-17 EP EP12306279.6A patent/EP2722338A1/en not_active Withdrawn
-
2013
- 2013-10-17 CN CN201911071187.3A patent/CN110923181A/zh active Pending
- 2013-10-17 EP EP13777082.2A patent/EP2909229B1/en active Active
- 2013-10-17 DK DK13777082.2T patent/DK2909229T3/en active
- 2013-10-17 EP EP18194351.5A patent/EP3459966B1/en active Active
- 2013-10-17 WO PCT/EP2013/071724 patent/WO2014060514A1/en not_active Ceased
- 2013-10-17 SG SG10201706392YA patent/SG10201706392YA/en unknown
- 2013-10-17 CA CA2887055A patent/CA2887055C/en active Active
- 2013-10-17 ES ES13777082T patent/ES2715651T3/es active Active
- 2013-10-17 CN CN201380053317.5A patent/CN104936976B/zh active Active
- 2013-10-17 DK DK18194351.5T patent/DK3459966T3/da active
- 2013-10-17 JP JP2015537248A patent/JP6473086B2/ja active Active
- 2013-10-17 AU AU2013333928A patent/AU2013333928B2/en active Active
- 2013-10-17 ES ES18194351T patent/ES2771675T3/es active Active
- 2013-10-17 SG SG11201502010TA patent/SG11201502010TA/en unknown
-
2015
- 2015-04-09 US US14/682,155 patent/US9528086B2/en active Active
-
2019
- 2019-01-24 JP JP2019009851A patent/JP6914976B2/ja active Active
-
2021
- 2021-07-14 JP JP2021116104A patent/JP7277516B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2909229A1 (en) | 2015-08-26 |
| HK1213926A1 (en) | 2016-07-15 |
| EP2722338A1 (en) | 2014-04-23 |
| CA2887055A1 (en) | 2014-04-24 |
| ES2771675T3 (es) | 2020-07-06 |
| JP6914976B2 (ja) | 2021-08-04 |
| JP6473086B2 (ja) | 2019-02-20 |
| CN104936976A (zh) | 2015-09-23 |
| SG11201502010TA (en) | 2015-04-29 |
| CN110923181A (zh) | 2020-03-27 |
| CA2887055C (en) | 2023-03-21 |
| AU2013333928A1 (en) | 2015-04-09 |
| EP3459966B1 (en) | 2019-11-27 |
| US9528086B2 (en) | 2016-12-27 |
| CN104936976B (zh) | 2019-11-22 |
| US20150210978A1 (en) | 2015-07-30 |
| JP7277516B2 (ja) | 2023-05-19 |
| SG10201706392YA (en) | 2017-09-28 |
| AU2013333928B2 (en) | 2017-11-30 |
| ES2715651T3 (es) | 2019-06-05 |
| DK3459966T3 (da) | 2020-02-17 |
| WO2014060514A1 (en) | 2014-04-24 |
| JP2021164481A (ja) | 2021-10-14 |
| EP3459966A1 (en) | 2019-03-27 |
| JP2015536134A (ja) | 2015-12-21 |
| EP2909229B1 (en) | 2018-12-12 |
| JP2019088303A (ja) | 2019-06-13 |
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