DK287977A - Fremgangsmade til fremstilling af 2-(3-(2-(thiazolyl-eller thiazolinyl)thio) phenyl)-alkan-(eller alken) syrer - Google Patents

Fremgangsmade til fremstilling af 2-(3-(2-(thiazolyl-eller thiazolinyl)thio) phenyl)-alkan-(eller alken) syrer

Info

Publication number
DK287977A
DK287977A DK287977A DK287977A DK287977A DK 287977 A DK287977 A DK 287977A DK 287977 A DK287977 A DK 287977A DK 287977 A DK287977 A DK 287977A DK 287977 A DK287977 A DK 287977A
Authority
DK
Denmark
Prior art keywords
thiazolinyl
thiazolyl
thio
alkene
alkane
Prior art date
Application number
DK287977A
Other languages
English (en)
Inventor
T Y Shen
N P Jensen
D H Minsker
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK287977A publication Critical patent/DK287977A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/19Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00Thiocarbonic acids; Halides, esters or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/16Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK287977A 1976-07-12 1977-06-28 Fremgangsmade til fremstilling af 2-(3-(2-(thiazolyl-eller thiazolinyl)thio) phenyl)-alkan-(eller alken) syrer DK287977A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70486376A 1976-07-12 1976-07-12

Publications (1)

Publication Number Publication Date
DK287977A true DK287977A (da) 1978-01-13

Family

ID=24831153

Family Applications (1)

Application Number Title Priority Date Filing Date
DK287977A DK287977A (da) 1976-07-12 1977-06-28 Fremgangsmade til fremstilling af 2-(3-(2-(thiazolyl-eller thiazolinyl)thio) phenyl)-alkan-(eller alken) syrer

Country Status (7)

Country Link
JP (1) JPS539765A (da)
DE (1) DE2731292A1 (da)
DK (1) DK287977A (da)
FR (1) FR2358402A1 (da)
GB (1) GB1543276A (da)
NL (1) NL7707161A (da)
SE (1) SE7707451L (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10224463A1 (de) 2002-06-03 2003-12-11 Bayer Ag Verfahren zur Herstellung von 5-Nitro-3,4-dihydro-1(2H)-naphthalinon, 1,5-Naphthalindiamin und 1,5-Naphthalindiisocyanat
JP6271766B2 (ja) 2014-02-03 2018-01-31 クワドリガ バイオサイエンシーズ, インコーポレイテッド 化学療法剤としてのβ置換γアミノ酸および類似体
MX2016010095A (es) 2014-02-03 2017-02-15 Quadriga Biosciences Inc Beta-aminoacidos beta-sustituidos y sus analogos como agentes quimioterapeuticos.
CN108026026B (zh) 2015-08-03 2021-02-09 夸德里加生物科学公司 作为化疗剂的β-取代的β-氨基酸和类似物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3890337A (en) * 1973-11-23 1975-06-17 Lilly Co Eli {60 ,{60 ,{60 -Trifluoro-2-nitro-6-{8 oxa(thia)zolyl{9 thio-p-tolunitriles

Also Published As

Publication number Publication date
JPS539765A (en) 1978-01-28
FR2358402B1 (da) 1980-02-29
FR2358402A1 (fr) 1978-02-10
GB1543276A (en) 1979-03-28
SE7707451L (sv) 1978-01-13
DE2731292A1 (de) 1978-01-19
NL7707161A (nl) 1978-01-16

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