DK2864473T3 - Stamceller og pankreatiske celler som kan anvendes til behandlingen af insulin-afhængig diabetes mellitus - Google Patents

Stamceller og pankreatiske celler som kan anvendes til behandlingen af insulin-afhængig diabetes mellitus Download PDF

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Publication number
DK2864473T3
DK2864473T3 DK13733516.2T DK13733516T DK2864473T3 DK 2864473 T3 DK2864473 T3 DK 2864473T3 DK 13733516 T DK13733516 T DK 13733516T DK 2864473 T3 DK2864473 T3 DK 2864473T3
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insulin
treatment
diabetes mellitus
cells
dependent diabetes
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DK13733516.2T
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Danish (da)
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William L Rust
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Seraxis Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/39—Pancreas; Islets of Langerhans
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0602—Vertebrate cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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DK13733516.2T 2012-06-26 2013-06-24 Stamceller og pankreatiske celler som kan anvendes til behandlingen af insulin-afhængig diabetes mellitus DK2864473T3 (da)

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US201261664259P 2012-06-26 2012-06-26
PCT/US2013/047243 WO2014004341A1 (en) 2012-06-26 2013-06-24 Stem cells and pancreatic cells useful for the treatment of insulin-dependent diabetes mellitus

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US (2) US9968639B2 (cg-RX-API-DMAC7.html)
EP (2) EP2864473B1 (cg-RX-API-DMAC7.html)
JP (2) JP6386453B2 (cg-RX-API-DMAC7.html)
KR (2) KR102058259B1 (cg-RX-API-DMAC7.html)
CN (2) CN104640979B (cg-RX-API-DMAC7.html)
AU (2) AU2013280698B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014031676A2 (cg-RX-API-DMAC7.html)
CA (1) CA2876677C (cg-RX-API-DMAC7.html)
DK (1) DK2864473T3 (cg-RX-API-DMAC7.html)
EA (2) EA033954B1 (cg-RX-API-DMAC7.html)
ES (1) ES2745704T3 (cg-RX-API-DMAC7.html)
IL (2) IL236346B (cg-RX-API-DMAC7.html)
IN (1) IN2015DN00281A (cg-RX-API-DMAC7.html)
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CN106467918B (zh) * 2015-08-18 2020-07-31 中国科学技术大学先进技术研究院 一种基于人皮肤细胞的胰岛素分泌细胞的诱导方法及应用
CN105434471A (zh) * 2015-11-26 2016-03-30 深圳爱生再生医学科技有限公司 治疗糖尿病的干细胞制剂及其制备方法
US11484554B2 (en) * 2018-02-09 2022-11-01 Seraxis, Inc. Pancreatic cells for treating diabetes and methods of generating the same
CN112888778B (zh) * 2018-10-15 2025-06-03 埃维亚生命科学有限公司 通过低分子化合物由源自内胚层组织或器官的细胞制备干细胞/祖细胞的方法
IL293803A (en) * 2019-12-11 2022-08-01 Univ Tokyo Induction of proliferating pancreatic islet-like germ cells by transient expression of mycl and induction of differentiation into insulin-positive cells
WO2023278382A1 (en) 2021-06-29 2023-01-05 Staffan Holmin Endoluminal delivery cannula
IL316370A (en) 2022-04-15 2024-12-01 Smartcella Solutions Ab COMPOSITIONS AND METHODS FOR EXOSOME-MEDIATED DELIVERY OF mRNA AGENTS
WO2024163938A1 (en) 2023-02-03 2024-08-08 Seraxis, Inc. Therapeutic cells and methods relating to the same
WO2025029826A1 (en) 2023-07-31 2025-02-06 Seraxis, Inc. Modified therapeutics cells and methods relating to the same

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EA201590088A1 (ru) 2015-04-30
JP6386453B2 (ja) 2018-09-05
PT2864473T (pt) 2019-09-27
JP6856586B2 (ja) 2021-04-07
CA2876677C (en) 2021-09-07
JP2015522281A (ja) 2015-08-06
KR102058259B1 (ko) 2019-12-23
EP2864473B1 (en) 2019-08-21
BR112014031676A2 (pt) 2017-10-31
US20150231181A1 (en) 2015-08-20
EA033954B1 (ru) 2019-12-13
CN113265370A (zh) 2021-08-17
IL236346A0 (en) 2015-02-26
EP3611255A1 (en) 2020-02-19
AU2013280698B2 (en) 2019-01-17
EP2864473A1 (en) 2015-04-29
US20130344594A1 (en) 2013-12-26
CA2876677A1 (en) 2014-01-03
IN2015DN00281A (cg-RX-API-DMAC7.html) 2015-06-12
AU2019202085A1 (en) 2019-04-18
US9474772B2 (en) 2016-10-25
EA201992135A1 (ru) 2020-02-05
KR20190141263A (ko) 2019-12-23
JP2018193394A (ja) 2018-12-06
IL266965A (en) 2019-07-31
SG11201408717XA (en) 2015-02-27
ES2745704T3 (es) 2020-03-03
CN104640979A (zh) 2015-05-20
KR102174581B1 (ko) 2020-11-06
WO2014004341A1 (en) 2014-01-03
AU2013280698A1 (en) 2015-01-22
US9968639B2 (en) 2018-05-15
CN104640979B (zh) 2021-05-04
KR20150036059A (ko) 2015-04-07
IL266965B (en) 2021-08-31

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