DK27885D0 - Fremstilling af peptider - Google Patents

Fremstilling af peptider

Info

Publication number
DK27885D0
DK27885D0 DK27885A DK27885A DK27885D0 DK 27885 D0 DK27885 D0 DK 27885D0 DK 27885 A DK27885 A DK 27885A DK 27885 A DK27885 A DK 27885A DK 27885 D0 DK27885 D0 DK 27885D0
Authority
DK
Denmark
Prior art keywords
derivatives
glucagon
expression
yeast
fragments
Prior art date
Application number
DK27885A
Other languages
English (en)
Other versions
DK27885A (da
Inventor
Kjeld Norris
Mogens Trier Hansen
Lars Thim
Alister James Moody
Fanny Norris
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK27885A priority Critical patent/DK27885A/da
Publication of DK27885D0 publication Critical patent/DK27885D0/da
Priority to EP86300384A priority patent/EP0189998B1/en
Priority to ES551042A priority patent/ES8708250A1/es
Priority to FI860251A priority patent/FI87800C/fi
Priority to GR860149A priority patent/GR860149B/el
Priority to PT81872A priority patent/PT81872B/pt
Priority to CA000499911A priority patent/CA1294232C/en
Priority to AT86300384T priority patent/ATE48643T1/de
Priority to MX1277A priority patent/MX163776B/es
Priority to AU52472/86A priority patent/AU587218B2/en
Priority to IE16286A priority patent/IE58726B1/en
Priority to DE8686300384T priority patent/DE3667488D1/de
Priority to JP61009822A priority patent/JPH0720435B2/ja
Priority to NO860178A priority patent/NO172185C/no
Priority to ZA86393A priority patent/ZA86393B/xx
Priority to DK28386A priority patent/DK156008C/da
Priority to NZ214883A priority patent/NZ214883A/en
Priority to US06/820,144 priority patent/US4826763A/en
Publication of DK27885A publication Critical patent/DK27885A/da
Priority to JP5255433A priority patent/JPH0746986B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK27885A 1985-01-22 1985-01-22 Fremstilling af peptider DK27885A (da)

Priority Applications (19)

Application Number Priority Date Filing Date Title
DK27885A DK27885A (da) 1985-01-22 1985-01-22 Fremstilling af peptider
ZA86393A ZA86393B (en) 1985-01-22 1986-01-20 Process for preparing glucagon or derivatives of fragments thereof in yeast
MX1277A MX163776B (es) 1985-01-22 1986-01-20 Procedimiento para preparar glucamon o sus derivados en una cepa de levadura transformada
IE16286A IE58726B1 (en) 1985-01-22 1986-01-20 A process for preparing glucagon or derivatives thereof in a transformed yeast strain
FI860251A FI87800C (fi) 1985-01-22 1986-01-20 Foerfarande foer framstaellning av glukagon i jaest
GR860149A GR860149B (en) 1985-01-22 1986-01-20 Process of preparing glucagon or derivatives thereof in a transformed yeast strain
PT81872A PT81872B (pt) 1985-01-22 1986-01-20 Processo para a preparacao de glucagon ou dos seus derivados em uma estirpe de levedura transformada
CA000499911A CA1294232C (en) 1985-01-22 1986-01-20 Process for preparing glucagon or derivatives or fragments thereof in yeast
AT86300384T ATE48643T1 (de) 1985-01-22 1986-01-20 Verfahren zur herstellung von glucagon oder dessen derivaten in einem transformierten hefestamm.
EP86300384A EP0189998B1 (en) 1985-01-22 1986-01-20 A process for preparing glucagon or derivatives thereof in a transformed yeast strain
AU52472/86A AU587218B2 (en) 1985-01-22 1986-01-20 Process for preparing glucagon or glucagon (1-21) in yeast
ES551042A ES8708250A1 (es) 1985-01-22 1986-01-20 Un procedimiento para producir glucagon o fragmentos o derivados del mismo en levadura
DE8686300384T DE3667488D1 (de) 1985-01-22 1986-01-20 Verfahren zur herstellung von glucagon oder dessen derivaten in einem transformierten hefestamm.
JP61009822A JPH0720435B2 (ja) 1985-01-22 1986-01-20 形質転換酵母におけるグルカゴンの製造方法
NO860178A NO172185C (no) 1985-01-22 1986-01-20 Fremgangsmaate for fremstilling av glukagon
US06/820,144 US4826763A (en) 1985-01-22 1986-01-21 Process for preparing glucagon or fragments or derivatives thereof in yeast
DK28386A DK156008C (da) 1985-01-22 1986-01-21 Fremgangsmaade til fremstilling a glucagon i en transformeret gaerstamme
NZ214883A NZ214883A (en) 1985-01-22 1986-01-21 Preparation of glucagon by transformant yeast strain
JP5255433A JPH0746986B2 (ja) 1985-01-22 1993-10-13 グルカゴンを生産する形質転換酵母

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK27885A DK27885A (da) 1985-01-22 1985-01-22 Fremstilling af peptider

Publications (2)

Publication Number Publication Date
DK27885D0 true DK27885D0 (da) 1985-01-22
DK27885A DK27885A (da) 1986-07-23

Family

ID=8091749

Family Applications (1)

Application Number Title Priority Date Filing Date
DK27885A DK27885A (da) 1985-01-22 1985-01-22 Fremstilling af peptider

Country Status (17)

Country Link
US (1) US4826763A (da)
EP (1) EP0189998B1 (da)
JP (2) JPH0720435B2 (da)
AT (1) ATE48643T1 (da)
AU (1) AU587218B2 (da)
CA (1) CA1294232C (da)
DE (1) DE3667488D1 (da)
DK (1) DK27885A (da)
ES (1) ES8708250A1 (da)
FI (1) FI87800C (da)
GR (1) GR860149B (da)
IE (1) IE58726B1 (da)
MX (1) MX163776B (da)
NO (1) NO172185C (da)
NZ (1) NZ214883A (da)
PT (1) PT81872B (da)
ZA (1) ZA86393B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151354A (en) * 1986-08-21 1992-09-29 Cornelius Hollenberg Fermentation processes using amylolytic enzyme producing microorganisms
DK175919B1 (da) * 1986-09-19 2005-06-27 Univ Washington Ekspression af biologisk aktiv faktor XIII
JPH01187499A (ja) * 1988-01-21 1989-07-26 Science & Tech Agency 原子炉解体用ロボット
IL93173A0 (en) * 1989-02-01 1990-11-05 Shionogi & Co Production of glucagon
US6172039B1 (en) 1990-04-16 2001-01-09 Apex Bioscience, Inc. Expression of recombinant hemoglobin and hemoglobin variants in yeast
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
US5510459A (en) * 1991-01-17 1996-04-23 Zymogenetics, Inc. Glucagon antagonists
US5408037A (en) * 1991-01-17 1995-04-18 Zymogenetics, Inc. Methods for detecting glucagon antagonists
EP0653965B1 (en) * 1992-07-06 1996-05-15 Beckman Instruments, Inc. Fluid delivery system uitlizing multiple port valve
DK144093D0 (da) * 1993-12-23 1993-12-23 Novo Nordisk As
US5652216A (en) * 1994-05-26 1997-07-29 Novo Nordisk A/S Pharmaceutical preparation
JP4699576B2 (ja) * 1997-05-16 2011-06-15 １１４９３３６ オンタリオ インコーポレーテッド 胃腸管上部の機能を強化する方法
MXPA05006994A (es) * 2002-12-27 2005-10-18 Diobex Inc Composiciones y metodos para la prevencion y el control de hipoglucemia inducida por insulina.
US7655618B2 (en) * 2002-12-27 2010-02-02 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
CN116925238A (zh) 2009-02-03 2023-10-24 阿穆尼克斯制药公司 延伸重组多肽和包含该延伸重组多肽的组合物
CA2764108A1 (en) 2009-06-08 2010-12-16 Amunix Operating Inc. Glucose-regulating polypeptides and methods of making and using same
CN117462693A (zh) 2012-02-27 2024-01-30 阿穆尼克斯运营公司 Xten缀合组合物和制造其的方法
US11396533B2 (en) 2018-10-09 2022-07-26 Fresenius Kabi Ipsum S.R.L. Process for the manufacture of GLP-1 analogues
EP3753946A1 (en) 2019-06-18 2020-12-23 Fresenius Kabi iPSUM S.r.l. Improved process for the preparation of high purity glucagon
CN114401981A (zh) 2019-06-18 2022-04-26 北京费森尤斯卡比医药有限公司 胰高血糖素制造方法
JP2023501478A (ja) 2019-11-13 2023-01-18 アミュニックス・ファーマシューティカルズ・インコーポレイテッド バーコード化されたｘｔｅｎポリペプチドおよびその組成物、ならびにその作製および使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401759A (en) * 1980-05-01 1983-08-30 Harvey Rubin Detection and isolation of glucagon mRNA using a synthetic oligodeoxynucleotide
DK283180A (da) * 1980-07-01 1982-01-02 Novo Industri As Polypeptider og derivater deraf
US4546082A (en) * 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins

Also Published As

Publication number Publication date
JPS61181398A (ja) 1986-08-14
ATE48643T1 (de) 1989-12-15
FI87800C (fi) 1993-02-25
NZ214883A (en) 1988-04-29
US4826763A (en) 1989-05-02
NO860178L (no) 1986-07-23
DK27885A (da) 1986-07-23
PT81872A (en) 1986-02-01
GR860149B (en) 1986-05-21
NO172185B (no) 1993-03-08
JPH0720435B2 (ja) 1995-03-08
DE3667488D1 (de) 1990-01-18
AU587218B2 (en) 1989-08-10
FI860251A (fi) 1986-07-23
FI87800B (fi) 1992-11-13
CA1294232C (en) 1992-01-14
ES8708250A1 (es) 1987-10-01
JPH06292594A (ja) 1994-10-21
ES551042A0 (es) 1987-10-01
ZA86393B (en) 1987-03-25
JPH0746986B2 (ja) 1995-05-24
FI860251A0 (fi) 1986-01-20
EP0189998A1 (en) 1986-08-06
EP0189998B1 (en) 1989-12-13
AU5247286A (en) 1986-07-31
MX163776B (es) 1992-06-22
NO172185C (no) 1993-06-16
IE860162L (en) 1986-07-22
PT81872B (pt) 1988-05-27
IE58726B1 (en) 1993-11-03

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