DK270077A - 6,7-benzomorphanderivater og fremgangsmade til deres fremstillling - Google Patents

6,7-benzomorphanderivater og fremgangsmade til deres fremstillling

Info

Publication number
DK270077A
DK270077A DK270077A DK270077A DK270077A DK 270077 A DK270077 A DK 270077A DK 270077 A DK270077 A DK 270077A DK 270077 A DK270077 A DK 270077A DK 270077 A DK270077 A DK 270077A
Authority
DK
Denmark
Prior art keywords
benzomorphand
derivatives
procedure
preparation
benzomorphand derivatives
Prior art date
Application number
DK270077A
Other languages
Danish (da)
English (en)
Inventor
A M Akkerman
H C C K Bakel
H G Breevoort-Uurbanus
Original Assignee
Acf Chemiefarma Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv
Publication of DK270077A publication Critical patent/DK270077A/da
Priority to DK255782A priority Critical patent/DK255782A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK270077A 1976-06-21 1977-06-17 6,7-benzomorphanderivater og fremgangsmade til deres fremstillling DK270077A (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK255782A DK255782A (da) 1976-06-21 1982-06-07 Fremgangsmaade til fremstilling af benzomorphanderivater og praeparater indeholdende disse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB25577/76A GB1575009A (en) 1976-06-21 1976-06-21 6,7-benzomorphan derivatives

Publications (1)

Publication Number Publication Date
DK270077A true DK270077A (da) 1977-12-22

Family

ID=10229936

Family Applications (1)

Application Number Title Priority Date Filing Date
DK270077A DK270077A (da) 1976-06-21 1977-06-17 6,7-benzomorphanderivater og fremgangsmade til deres fremstillling

Country Status (11)

Country Link
US (2) US4234591A (en:Method)
JP (1) JPS52156869A (en:Method)
BE (1) BE855938A (en:Method)
CH (1) CH634562A5 (en:Method)
DE (1) DE2726836A1 (en:Method)
DK (1) DK270077A (en:Method)
FR (1) FR2355830A1 (en:Method)
GB (1) GB1575009A (en:Method)
IE (1) IE44938B1 (en:Method)
LU (1) LU77585A1 (en:Method)
NL (1) NL7706328A (en:Method)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2460298A1 (fr) * 1979-06-28 1981-01-23 Sterling Drug Inc Procede de preparation de 2,6-methano-3-benzazocines
DE19907874A1 (de) * 1999-02-23 2000-08-24 Boehringer Ingelheim Pharma N-(5-Phenyl-tetrahydrofuranyl)methyl- und N-(6-Phenyl-tetrahydropyranyl)methyl substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
EP1506174B1 (en) 2002-05-17 2015-09-30 Taiwanj Pharmaceuticals Co., Ltd. Use of naltrexone for treating kidney and liver damage
US7923454B2 (en) * 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
TW201431842A (zh) * 2012-11-09 2014-08-16 Purdue Pharma Lp 苯並嗎啡烷類似物及其應用
WO2014118618A1 (en) * 2013-01-31 2014-08-07 Purdue Pharma L.P. Benzomorphan analogs and the use thereof
MA39956A (fr) * 2014-05-06 2015-11-12 Purdue Pharma Lp Analogues du benzomorphane et leur utilisation

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (en:Method) * 1958-09-22
NL130089C (en:Method) * 1963-11-07
US3639407A (en) * 1965-05-05 1972-02-01 Geigy Chem Corp Novel 1 2 3 4 5 6-hexahydro-6-phenyl-2 6-methano-3-benzazocines
DE1545827C3 (de) * 1965-06-25 1975-09-11 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von 6,7-Benzomorphanen
US3499906A (en) * 1966-05-20 1970-03-10 Merck & Co Inc 5,9-diethyl-2'-hydroxy-2-substituted-6,7-benzomorphans
SE394277B (sv) * 1967-06-07 1977-06-20 Sumitomo Chemical Co Forfarande for framstellning av 6,7-bensomorfanderivat
US3553223A (en) * 1968-01-05 1971-01-05 Hoffmann La Roche Acid catalyzed cyclization of tetrahydropyridines containing an electron withdrawing group on the nitrogen
US3639410A (en) * 1968-07-26 1972-02-01 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro - 8 - substituted-6-alkyl-11-(h or a lkyl) - 26-methano-3-benzazocines
US3511846A (en) * 1968-12-16 1970-05-12 Geigy Chem Corp Process for the preparation of optically active benzazocines
BR6914879D0 (pt) * 1969-01-23 1973-02-08 Merck & Co Inc Processos quimicos
CS166802B2 (en:Method) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
DE2217420C3 (de) * 1972-04-12 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) * 1972-06-19 1974-01-31 Boehringer Sohn Ingelheim 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
US4108857A (en) * 1975-08-18 1978-08-22 Sterling Drug Inc. Imidazolylmethyl methanobenzazocines
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
LU77585A1 (en:Method) 1977-09-29
GB1575009A (en) 1980-09-17
JPS52156869A (en) 1977-12-27
FR2355830A1 (fr) 1978-01-20
US4288444A (en) 1981-09-08
CH634562A5 (de) 1983-02-15
DE2726836A1 (de) 1977-12-29
FR2355830B1 (en:Method) 1981-04-30
NL7706328A (nl) 1977-12-23
IE44938B1 (en) 1982-05-19
IE44938L (en) 1977-12-21
BE855938A (nl) 1977-12-21
US4234591A (en) 1980-11-18

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