DK2572724T3 - Treatment of fibrosis and liver disease - Google Patents
Treatment of fibrosis and liver disease Download PDFInfo
- Publication number
- DK2572724T3 DK2572724T3 DK12192755.2T DK12192755T DK2572724T3 DK 2572724 T3 DK2572724 T3 DK 2572724T3 DK 12192755 T DK12192755 T DK 12192755T DK 2572724 T3 DK2572724 T3 DK 2572724T3
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- DK
- Denmark
- Prior art keywords
- ace2
- fibrosis
- leu
- glu
- ala
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| Application Number | Priority Date | Filing Date | Title |
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| EP07450239A EP2077119A1 (de) | 2007-12-21 | 2007-12-21 | Behandlung von Fibrosen und Lebererkrankungen |
| EP08869561.4A EP2227246B1 (de) | 2007-12-21 | 2008-12-22 | Behandlung von fibrosen und lebererkrankungen |
Publications (1)
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| DK2572724T3 true DK2572724T3 (en) | 2018-06-06 |
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| DK12192755.2T DK2572724T3 (en) | 2007-12-21 | 2008-12-22 | Treatment of fibrosis and liver disease |
| DK08869561.4T DK2227246T3 (da) | 2007-12-21 | 2008-12-22 | Behandling af fibroser og leversygdomme |
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| DK08869561.4T DK2227246T3 (da) | 2007-12-21 | 2008-12-22 | Behandling af fibroser og leversygdomme |
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| EP (3) | EP2077119A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5706163B2 (cg-RX-API-DMAC7.html) |
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| CA (1) | CA2709895C (cg-RX-API-DMAC7.html) |
| DK (2) | DK2572724T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2671556T3 (cg-RX-API-DMAC7.html) |
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| NZ (1) | NZ586265A (cg-RX-API-DMAC7.html) |
| PL (2) | PL2227246T3 (cg-RX-API-DMAC7.html) |
| PT (2) | PT2572724T (cg-RX-API-DMAC7.html) |
| TR (1) | TR201807891T4 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009086572A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8557958B1 (en) | 2012-06-18 | 2013-10-15 | Tarix Pharmaceuticals Ltd. | Compositions and methods for treatment of diabetes |
| US8633158B1 (en) | 2012-10-02 | 2014-01-21 | Tarix Pharmaceuticals Ltd. | Angiotensin in treating brain conditions |
| US9333233B2 (en) | 2014-02-25 | 2016-05-10 | Tarix Pharmaceuticals Ltd. | Methods and compositions for the delayed treatment of stroke |
| TWI895357B (zh) * | 2020-02-20 | 2025-09-01 | 理筱龍 | 人參皂甙ｍ１作為血管收縮素調節酶的調節劑及其在治療包括冠狀病毒引起的症狀之疾病或病徵的用途 |
| WO2023102156A1 (en) | 2021-12-03 | 2023-06-08 | Wisconsin Alumni Research Foundation | Mutant ace2 proteins and methods of using same |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP0138854B1 (en) * | 1983-03-08 | 1992-11-04 | Chiron Mimotopes Pty. Ltd. | Antigenically active amino acid sequences |
| US4935352A (en) * | 1985-10-21 | 1990-06-19 | Takeda Chemical Industries, Ltd. | Expression vector for animal cell line and use thereof |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5672344A (en) * | 1987-12-30 | 1997-09-30 | The Regents Of The University Of Michigan | Viral-mediated gene transfer system |
| US5399346A (en) * | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5436146A (en) * | 1989-09-07 | 1995-07-25 | The Trustees Of Princeton University | Helper-free stocks of recombinant adeno-associated virus vectors |
| US5670488A (en) * | 1992-12-03 | 1997-09-23 | Genzyme Corporation | Adenovirus vector for gene therapy |
| US5529774A (en) * | 1991-08-13 | 1996-06-25 | The Regents Of The University Of California | In vivo transfer of the HSV-TK gene implanted retroviral producer cells |
| NZ244306A (en) * | 1991-09-30 | 1995-07-26 | Boehringer Ingelheim Int | Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation |
| US5582995A (en) * | 1993-06-11 | 1996-12-10 | The General Hospital Corporation | Methods of screening for compounds which inhibit the direct binding of Ras to Raf |
| US5645829A (en) * | 1993-06-18 | 1997-07-08 | Beth Israel Hospital Association | Mesothelial cell gene therapy |
| US5714353A (en) * | 1994-05-24 | 1998-02-03 | Research Corporation Technologies, Inc. | Safe vectors for gene therapy |
| US6071890A (en) * | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| US5591591A (en) * | 1995-02-09 | 1997-01-07 | Tropix, Inc. | Dioxetane compounds for the chemiluminescent detection of proteases, methods of use and kits therefore |
| EP0760682A4 (en) * | 1995-02-28 | 1998-09-09 | Univ California | ANGIOGENIC THERAPY BY GENE TRANSFER |
| US6306830B1 (en) * | 1996-09-05 | 2001-10-23 | The Regents Of The University Of California | Gene therapy for congestive heart failure |
| US6224584B1 (en) * | 1997-01-14 | 2001-05-01 | Eclipse Surgical Technologies, Inc. | Therapeutic and diagnostic agent delivery |
| US5792851A (en) * | 1996-09-03 | 1998-08-11 | Albert Einstin College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Human prostaglandin transporter |
| US5851788A (en) * | 1997-01-31 | 1998-12-22 | The Burnham Institute | Nucleic acid encoding a family of acetyl-coenzyme-A transporter proteins, and products related thereto |
| US6037137A (en) * | 1997-02-20 | 2000-03-14 | Oncoimmunin, Inc. | Fluorogenic peptides for the detection of protease activity |
| US6989363B1 (en) | 1997-12-11 | 2006-01-24 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| US6610497B1 (en) * | 1997-12-11 | 2003-08-26 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| US6194556B1 (en) * | 1997-12-11 | 2001-02-27 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor |
| US5997509A (en) * | 1998-03-06 | 1999-12-07 | Cornell Research Foundation, Inc. | Minimally invasive gene therapy delivery device and method |
| EP1183019A2 (en) * | 1999-04-30 | 2002-03-06 | Millennium Pharmaceuticals, Inc. | Ace-2 inhibiting compounds and methods of use thereof |
| DE10023923A1 (de) * | 1999-06-10 | 2000-12-14 | Aventis Behring Gmbh | Verfahren zur Bestimmung der Aktivität der Faktor VII-aktivierenden Protease aus Proteinlösungen |
| US6900033B2 (en) * | 2001-06-04 | 2005-05-31 | Human Genome Sciences, Inc. | Methods and compositions for modulating ACE-2 activity |
| US7794707B2 (en) | 2002-06-19 | 2010-09-14 | University Health Network | ACE2 activation for treatment of heart, lung and kidney disease and hypertension |
| WO2005097109A1 (en) * | 2004-04-01 | 2005-10-20 | Daniel Batlle | Methods for achieving a protective ace2 expression level |
| US20050287066A1 (en) * | 2004-06-28 | 2005-12-29 | Monoace, Inc. | Anti-rat angiotensin I-converting enzyme (ACE, CD143) monoclonal antibodies and uses thereof |
| CA2520514A1 (en) * | 2005-04-04 | 2006-10-04 | Monash University | Detection of plasma ace2 |
| EP1723962A1 (en) | 2005-05-19 | 2006-11-22 | IMBA-Institut für Molekulare Biotechnologie GmbH | Use of inhibitors of the renin-angiotensin system for the treatment of lung injuries |
| US7842709B2 (en) * | 2006-09-08 | 2010-11-30 | Ore Pharmaceuticals Inc. | Method for treating inflammatory diseases of the digestive tract |
| AT505262A1 (de) * | 2007-06-12 | 2008-12-15 | Apeiron Biolog Forschungs Und | Rekombinantes ace2 polypeptid |
| AT506258A1 (de) * | 2007-12-18 | 2009-07-15 | Apeiron Biolog Forschungs Und | Behandlung inflammatorischer krankheiten |
-
2007
- 2007-12-21 EP EP07450239A patent/EP2077119A1/de not_active Withdrawn
-
2008
- 2008-12-22 AU AU2008347208A patent/AU2008347208B9/en active Active
- 2008-12-22 NZ NZ586265A patent/NZ586265A/en unknown
- 2008-12-22 PT PT121927552T patent/PT2572724T/pt unknown
- 2008-12-22 EP EP08869561.4A patent/EP2227246B1/de active Active
- 2008-12-22 ES ES12192755.2T patent/ES2671556T3/es active Active
- 2008-12-22 TR TR2018/07891T patent/TR201807891T4/tr unknown
- 2008-12-22 PT PT88695614T patent/PT2227246E/pt unknown
- 2008-12-22 NO NO12192755A patent/NO2572724T3/no unknown
- 2008-12-22 DK DK12192755.2T patent/DK2572724T3/en active
- 2008-12-22 CA CA2709895A patent/CA2709895C/en active Active
- 2008-12-22 JP JP2010538269A patent/JP5706163B2/ja active Active
- 2008-12-22 WO PCT/AT2008/000472 patent/WO2009086572A1/de not_active Ceased
- 2008-12-22 DK DK08869561.4T patent/DK2227246T3/da active
- 2008-12-22 US US12/808,859 patent/US20100316624A1/en not_active Abandoned
- 2008-12-22 PL PL08869561T patent/PL2227246T3/pl unknown
- 2008-12-22 EP EP12192755.2A patent/EP2572724B1/de active Active
- 2008-12-22 PL PL12192755T patent/PL2572724T3/pl unknown
- 2008-12-22 ES ES08869561.4T patent/ES2481645T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2227246B1 (de) | 2014-06-04 |
| ES2671556T3 (es) | 2018-06-07 |
| WO2009086572A1 (de) | 2009-07-16 |
| PL2227246T3 (pl) | 2014-10-31 |
| EP2572724A1 (de) | 2013-03-27 |
| US20100316624A1 (en) | 2010-12-16 |
| NZ586265A (en) | 2012-06-29 |
| TR201807891T4 (tr) | 2018-06-21 |
| JP2011505843A (ja) | 2011-03-03 |
| DK2227246T3 (da) | 2014-08-25 |
| NO2572724T3 (cg-RX-API-DMAC7.html) | 2018-08-11 |
| EP2572724B1 (de) | 2018-03-14 |
| PT2227246E (pt) | 2014-09-02 |
| AU2008347208A1 (en) | 2009-07-16 |
| CA2709895A1 (en) | 2009-07-16 |
| CA2709895C (en) | 2017-10-31 |
| PL2572724T3 (pl) | 2018-08-31 |
| PT2572724T (pt) | 2018-06-14 |
| EP2227246A1 (de) | 2010-09-15 |
| EP2077119A1 (de) | 2009-07-08 |
| AU2008347208B2 (en) | 2014-05-22 |
| ES2481645T3 (es) | 2014-07-31 |
| JP5706163B2 (ja) | 2015-04-22 |
| AU2008347208B9 (en) | 2014-06-19 |
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