DK2542663T3 - Cirkulationssystem - Google Patents

Cirkulationssystem

Info

Publication number
DK2542663T3
DK2542663T3 DK11741408.6T DK11741408T DK2542663T3 DK 2542663 T3 DK2542663 T3 DK 2542663T3 DK 11741408 T DK11741408 T DK 11741408T DK 2542663 T3 DK2542663 T3 DK 2542663T3
Authority
DK
Denmark
Prior art keywords
circulation system
circulation
Prior art date
Application number
DK11741408.6T
Other languages
English (en)
Inventor
Uwe Marx
Gerd Lindner
Reyk Horland
Silke Hoffmann
Roland Lauster
Original Assignee
Tissuse Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tissuse Gmbh filed Critical Tissuse Gmbh
Application granted granted Critical
Publication of DK2542663T3 publication Critical patent/DK2542663T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C12M29/08—Air lift
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
DK11741408.6T 2010-08-06 2011-08-05 Cirkulationssystem DK2542663T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37136810P 2010-08-06 2010-08-06
EP10008244 2010-08-06
PCT/EP2011/003940 WO2012016711A1 (en) 2010-08-06 2011-08-05 Circulation system

Publications (1)

Publication Number Publication Date
DK2542663T3 true DK2542663T3 (da) 2014-10-13

Family

ID=43414165

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11741408.6T DK2542663T3 (da) 2010-08-06 2011-08-05 Cirkulationssystem

Country Status (14)

Country Link
US (1) US9506024B2 (da)
EP (1) EP2542663B1 (da)
JP (1) JP6004442B2 (da)
CN (1) CN103080296B (da)
AU (1) AU2011287881B2 (da)
CA (1) CA2807438C (da)
DK (1) DK2542663T3 (da)
EA (1) EA023707B1 (da)
ES (1) ES2508615T3 (da)
HK (1) HK1180715A1 (da)
PL (1) PL2542663T3 (da)
PT (1) PT2542663E (da)
SG (1) SG187214A1 (da)
WO (1) WO2012016711A1 (da)

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JP5415538B2 (ja) 2008-07-16 2014-02-12 チルドレンズ メディカル センター コーポレーション マイクロチャネルを有する臓器模倣装置ならびにその使用および製造方法
WO2013086486A1 (en) 2011-12-09 2013-06-13 President And Fellows Of Harvard College Integrated human organ-on-chip microphysiological systems
EP2628791A1 (de) * 2012-02-17 2013-08-21 Charité - Universitätsmedizin Berlin Perfusionsmodul für die Co-Kultur von Endothelzellen und Glattmuskelzellen zur Bestimmung pathosphysiologischer Veränderungen
EP2634251A1 (en) 2012-02-29 2013-09-04 Technische Universität Berlin 3D in vitro bi-phasic cartilage-bone construct
CA2866267A1 (en) 2012-03-06 2013-09-12 The Uab Research Foundation Three-dimesional, prevascularized, engineered tissue constructs, methods of making and methods of using the tissue constructs
SG10201608522XA (en) * 2012-04-26 2017-01-27 Tissuse Gmbh Methods for determining and/or monitoring conditions of a three dimensional cell culture system and optical sensor device for conducting said methods
ES2529994T3 (es) 2012-09-28 2015-02-25 Tissuse Gmbh Chip para múltiples órganos con una vida útil y homeostasis mejoradas
US9580678B2 (en) * 2013-06-21 2017-02-28 The Regents Of The University Of California Microfluidic tumor tissue dissociation device
DE102013011768B4 (de) 2013-07-10 2015-07-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Zirkulationssystem sowie Verfahren zur Vitalversorgung von Zellkulturen in einem mikrofluidischen Netzwerk
DE102013114634A1 (de) * 2013-12-20 2015-06-25 Karlsruher Institut für Technologie Mikrofluidischer Bioreaktor mit modularem Aufbau zur Synthese von Zellmetaboliten, das Verfahren zur Nutzung sowie dessen Verwendung
NL2014840B1 (en) * 2015-05-21 2017-01-31 Intecrypt B V Microfluidic device for in vitro 3D cell culture experimentation.
ITUB20153908A1 (it) * 2015-09-25 2017-03-25 Eltek Spa Apparato, sistema e metodo per la disgregazione di un tessuto biologico
CN105498005B (zh) * 2016-01-22 2017-08-11 浙江省人民医院 一种人工肝用去细胞支架生物反应器及其使用方法
US10722540B1 (en) 2016-02-01 2020-07-28 The Regents Of The University Of California Microfluidic device and method for shear stress-induced transformation of cells
WO2017199387A1 (ja) 2016-05-19 2017-11-23 光次 斉藤 培養装置および培養方法、並びにこの培養方法により製造された培養臓器
CN109475669B (zh) * 2016-05-24 2022-01-04 苏马瓦克医疗解决方案公司 用于在手术后收集内部液体的带有一次性储存器的便携式设备
KR20230084308A (ko) * 2016-08-03 2023-06-12 웨이크 포리스트 유니버시티 헬스 사이언시즈 암 모델링 플랫폼 및 그를 사용하는 방법
CN106497783B (zh) * 2016-09-01 2019-03-22 奥凯（苏州）生物技术有限公司 一种动态循环细胞培养器及细胞培养方法
CN106497784B (zh) * 2016-09-01 2019-03-22 奥凯（苏州）生物技术有限公司 一种实现培养液和废液交换的压力控制系统及其压力控制方法
CN106635790B (zh) * 2016-09-01 2019-02-26 奥凯（苏州）生物技术有限公司 一种全封闭自动化细胞培养系统
US10982181B2 (en) * 2016-09-07 2021-04-20 Triad National Security, Llc Devices for cell culture and methods of making and using the same
EP3525584B1 (en) * 2016-10-14 2023-05-03 Wake Forest University Health Sciences Multi-organ "body on a chip" apparatus utilizing a common media
JP6950887B2 (ja) * 2017-04-28 2021-10-13 米満　吉和 体外型の人工肝臓、及び体外型の人工肝臓用又は肝細胞培養用の器具
US20210197191A1 (en) * 2017-08-28 2021-07-01 The Regents Of The University Of California Microfluidic device for the digestion of tissues into cellular suspensions
US10926257B2 (en) * 2017-08-28 2021-02-23 The Regents Of The University Of California Microfluidic device for the digestion of tissues into cellular suspensions
WO2019178073A1 (en) * 2018-03-12 2019-09-19 North Carolina State University Vascular development monitoring systems and uses thereof
WO2019191111A1 (en) * 2018-03-26 2019-10-03 The Trustees Of The University Of Pennsylvania Systems and methods for multilane vasculature
RU192234U1 (ru) * 2018-06-29 2019-09-09 Общество с ограниченной ответственностью "Микрофлюидные технологии" Проточный чип для моделирования участка сосудистого русла для испытания имплантатов и оборудования для сердечно-сосудистой хирургии
CN111394245A (zh) 2018-12-12 2020-07-10 中科芯瑞(苏州)生物科技有限公司 用于筛选对内皮糖萼相关疾病具有预防和治疗活性的化合物的方法和装置
KR102267433B1 (ko) * 2019-07-29 2021-06-21 연세대학교 산학협력단 세포배양 플레이트
KR102222074B1 (ko) * 2020-04-28 2021-03-03 (주)아크에이르 장기 칩 시험 시스템

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DE4218917C2 (de) * 1992-06-10 1996-07-11 Schmitz Klaus Peter Dr Ing Hab Zellkulturmatrix
DE60017900T2 (de) * 1999-04-30 2006-04-06 Massachusetts General Hospital, Boston Herstellung von dreidimensionalem vaskularisierten gewebe mittels der verwendung von zweidimensionalen mikrohergestellten formen
US7371400B2 (en) * 2001-01-02 2008-05-13 The General Hospital Corporation Multilayer device for tissue engineering
GB0121986D0 (en) * 2001-09-11 2001-10-31 Isis Innovation Method and structure for growing living organic tissue
US7645253B2 (en) * 2001-11-16 2010-01-12 National Quality Care, Inc. Wearable ultrafiltration device
US7622298B2 (en) * 2006-03-24 2009-11-24 Norits, Inc. Method for creating perfusable microvessel systems
DE102006031871B4 (de) * 2006-07-10 2008-10-23 Gerlach, Jörg, Dr.med. 3-D Petri-Schale zur Züchtung und Untersuchung von Zellen

Also Published As

Publication number Publication date
AU2011287881B2 (en) 2014-07-24
EP2542663A1 (en) 2013-01-09
EA023707B1 (ru) 2016-07-29
HK1180715A1 (en) 2013-10-25
PT2542663E (pt) 2014-10-07
AU2011287881A1 (en) 2013-02-14
CN103080296B (zh) 2015-03-25
EP2542663B1 (en) 2014-07-16
JP2013532484A (ja) 2013-08-19
ES2508615T3 (es) 2014-10-16
EA201390147A1 (ru) 2013-08-30
CA2807438A1 (en) 2012-02-09
JP6004442B2 (ja) 2016-10-05
PL2542663T3 (pl) 2015-01-30
CA2807438C (en) 2020-09-01
SG187214A1 (en) 2013-02-28
CN103080296A (zh) 2013-05-01
US9506024B2 (en) 2016-11-29
US20130295598A1 (en) 2013-11-07
WO2012016711A1 (en) 2012-02-09

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