DK2445558T3 - Inhalator - Google Patents

Inhalator Download PDF

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Publication number
DK2445558T3
DK2445558T3 DK10727359.1T DK10727359T DK2445558T3 DK 2445558 T3 DK2445558 T3 DK 2445558T3 DK 10727359 T DK10727359 T DK 10727359T DK 2445558 T3 DK2445558 T3 DK 2445558T3
Authority
DK
Denmark
Prior art keywords
inhaler
chamber
amino
phenyl
aerosol
Prior art date
Application number
DK10727359.1T
Other languages
English (en)
Inventor
Joachim Karle
Albrecht Fenner
Bastian Fischer
Frank Herrmann
Holger Krenz
Nicole Mohren
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42727644&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2445558(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Application granted granted Critical
Publication of DK2445558T3 publication Critical patent/DK2445558T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0015—Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0024—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with an on-off output signal, e.g. from a switch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8275—Mechanical
    • A61M2205/8281—Mechanical spring operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2250/00—Specially adapted for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Claims (15)

1. Bærbar inhalator (1) til drivmiddelfri afmålt forstøvning af en medikamentfremstilling (2), fortrinsvis til et dyr, især en hest (32), hvilken har en trykgenerator (5), hvilken fortrinsvis er i form af en pumpe, og/eller hvilken fortrinsvis fungerer mekanisk og hvilken har en uddrivningsdyse (12) til fremføring af den forstøvede medikamentfremstilling (2) som en aerosol (14), hvilken trykgenerator (5) har en drivfjeder (7) til trykdannelse og forstøvning, hvilken inhalator (1) har en spændeanordning (38) til spænding af drivfjederen (7), kendetegnet ved at inhalatoren (1) eller spændeanordningen (38) er konstrueret til at betjenes med én hånd, hvor spændeanordningen (38) omfatter et manuelt betjent aktuatorelement (39), hvilket er drejeligt ved påvirkning, hvor spændeanordningen (38) omfatter et koblingselement (43) til omdannelse af bevægelse af aktuatorelementet (39) ved påvirkning til en spændebevægelse til at spænde drivfjederen (7), og hvor koblingselementet (43) er konfigureret til at omdanne den drejende bevægelse af aktuatorelementet (39) til en lineær bevægelse.
2. Inhalator ifølge krav 1, kendetegnet ved, at tilføjelsesenheden (23) eller kammeret (24) er cylindrisk, aflangt eller konisk i konstruktion.
3. Inhalator ifølge krav 1 eller 2, kendetegnet ved, at forbinderen (25) til at give adgang for aerosolen (14) er anbragt mellem modsatte ender af kammeret (24) eller åbner lateralt ind i kammeret (24).
4. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at kammeret (24) har et volumen af mere end 0,2 I, fortrinsvis mere end 0,25 I, især cirka 0,3 til 0,6 I.
5. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at tilføjelsesenheden (23) har en indgangsåbning (28) til at give adgang for lufttilførsel ind i kammeret (24), hvilken indgangsåbning (28) er anbragt opstrøms for forbinderen (25) for at tillade aerosolen (14) ind i kammeret (24).
6. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at indåndingsindikatoren (30) fungerer mekanisk og/eller omfatter et element, som kan afbøjes eller drejes ved strømmen af luft.
7. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at dispenseringsanordningen (27) omfatter eller danner et blødt endestykke, der har en udgang (33).
8. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at dispenseringsanordningen (27) er konstrueret som en nasal adapter til indsættelse i et næsebor (31) af en hest (32) eller øvrigt dyr.
9. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at inhalatoren (1) omfatter midler til mekanisk rensning af uddrivningsdysen (12).
10. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at midlerne omfatter et drejeelement (36) og/eller et renseelement (37).
11. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at trykdannelse eller forstøvning udføres ved fjederkraft.
12. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at inhalatoren (1) omfatter en tilføjelsesenhed (23) med et kammer (24) til modtagelse og/eller midlertidig opbevaring af aerosolen (14), hvilken inhalator (1) har mindst ét af følgende træk: (a) indførelse af aerosolen (14) ind i kammeret (24) finder sted ved rette vinkler på en primær dispenseringsretning og/eller langsgående retning af kammeret (24); (b) tilføjelsesenheden (23) omfatter en indgangsventil (29) til at give adgang for lufttilførsel ind i kammeret (24) og til at hindre strømning i den modsatte retning, hvilken indgangsventil (29) er anbragt opstrøms for en forbinder (25) til at give adgang for aerosolen (14) ind i kammeret (24); (c) tilføjelsesenheden (23) omfatter en indåndingsindikator (30) til at indikere en strøm af luft gennem kammeret (24) i den dispenserende retning; (d) tilføjelsesenheden (23) omfatter en dispenserende forbindelse (26) til at forbinde til en dispenseringsanordning (27) udelukkende i en defineret rotationsposition; (e) inhalatoren (1) omfatter en dispenseringsanordning (27), hvilken kan være forbundet til tilføjelsesenheden (23) eller er dannet derved, hvilken dispenseringsanordning (27) har en større diameter eller tværsnit end kammeret (24); (f) inhalatoren (1) er konstrueret til at være i stand til at spændes og frigives ved anvendelse af én hånd; (g) inhalatoren (1) omfatter et udløsningselement (8), hvilket er anbragt i den langsgående retning af kammeret (24); (h) inhalatoren (1) omfatter midler til at dække og/eller rense uddrivningsdysen (12).
13. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at spændeanordningen (38) omfatter et aktuatorelement (39), som kan betjenes manuelt for at spænde drivfjederen (7), hvilket aktuatorelement (39) især er drejeligt og/eller flytbart på en lineær måde.
14. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at inhalatoren (1) er konstrueret, således at aerosolen (14) fremføres ved lav hastighed, især ved en hastighed af mindre end 2 m/s, især fortrinsvis cirka 1,6 m/s eller mindre, ved en afstand af 10 cm fra uddrivningsdysen (12).
15. Inhalator ifølge et hvilket som helst af de foregående krav, kendetegnet ved, at inhalatoren (1) er konstrueret til at uddrive og forstøve 10 til 50 pi af medikament- fremstillingen (2) pr. påvirkning eller dosis over et tidsrum af mere end 0,7 s, især i alt væsentligt 1 s eller mere.
DK10727359.1T 2009-06-25 2010-06-14 Inhalator DK2445558T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09008341 2009-06-25
PCT/EP2010/003522 WO2010149280A1 (en) 2009-06-25 2010-06-14 Inhaler

Publications (1)

Publication Number Publication Date
DK2445558T3 true DK2445558T3 (da) 2016-09-19

Family

ID=42727644

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10727359.1T DK2445558T3 (da) 2009-06-25 2010-06-14 Inhalator

Country Status (19)

Country Link
US (1) US9084660B2 (da)
EP (1) EP2445558B1 (da)
JP (2) JP2012530567A (da)
KR (1) KR101641520B1 (da)
CN (2) CN102458541A (da)
AR (1) AR077248A1 (da)
AU (1) AU2010265187B2 (da)
BR (1) BRPI1011813B1 (da)
CA (1) CA2764469C (da)
CL (1) CL2011003298A1 (da)
CO (1) CO6480981A2 (da)
DK (1) DK2445558T3 (da)
ES (1) ES2593428T3 (da)
MX (1) MX2011013077A (da)
NZ (1) NZ596456A (da)
SG (1) SG176961A1 (da)
TW (1) TWI526198B (da)
WO (1) WO2010149280A1 (da)
ZA (1) ZA201108257B (da)

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CA2764469C (en) 2017-10-03
JP2015157178A (ja) 2015-09-03
CN104799969A (zh) 2015-07-29
KR101641520B1 (ko) 2016-07-21
WO2010149280A1 (en) 2010-12-29
CA2764469A1 (en) 2010-12-29
US20120103326A1 (en) 2012-05-03
BRPI1011813A2 (pt) 2016-03-29
SG176961A1 (en) 2012-02-28
ES2593428T3 (es) 2016-12-09
TWI526198B (zh) 2016-03-21
KR20120098404A (ko) 2012-09-05
NZ596456A (en) 2014-01-31
ZA201108257B (en) 2012-08-29
CO6480981A2 (es) 2012-07-16
CN102458541A (zh) 2012-05-16
EP2445558B1 (en) 2016-06-29
CN104799969B (zh) 2018-11-06
AU2010265187A1 (en) 2011-12-08
TW201103504A (en) 2011-02-01
JP2012530567A (ja) 2012-12-06
US9084660B2 (en) 2015-07-21
BRPI1011813B1 (pt) 2020-08-04
AR077248A1 (es) 2011-08-10
MX2011013077A (es) 2012-01-20
EP2445558A1 (en) 2012-05-02
CL2011003298A1 (es) 2012-05-11
AU2010265187B2 (en) 2015-05-14
JP6067784B2 (ja) 2017-01-25

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