DK238484A - 1-(4'-forgrenet alkylsulfonylphenyl)-6-chlor-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepiner - Google Patents

1-(4'-forgrenet alkylsulfonylphenyl)-6-chlor-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepiner Download PDF

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Publication number
DK238484A
DK238484A DK238484A DK238484A DK238484A DK 238484 A DK238484 A DK 238484A DK 238484 A DK238484 A DK 238484A DK 238484 A DK238484 A DK 238484A DK 238484 A DK238484 A DK 238484A
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DK
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Prior art keywords
benzazepines
dihydroxy
alkylsulfonylphenyl
chlor
tetrahydro
Prior art date
Application number
DK238484A
Other languages
Danish (da)
English (en)
Other versions
DK238484D0 (da
Inventor
Pamela Anne Chambers
Joseph Weinstock
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK238484D0 publication Critical patent/DK238484D0/da
Publication of DK238484A publication Critical patent/DK238484A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Epoxy Compounds (AREA)
DK238484A 1983-05-25 1984-05-14 1-(4'-forgrenet alkylsulfonylphenyl)-6-chlor-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepiner DK238484A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/498,351 US4514394A (en) 1983-05-25 1983-05-25 Anti-hypertensive use of 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines

Publications (2)

Publication Number Publication Date
DK238484D0 DK238484D0 (da) 1984-05-14
DK238484A true DK238484A (da) 1984-11-26

Family

ID=23980717

Family Applications (1)

Application Number Title Priority Date Filing Date
DK238484A DK238484A (da) 1983-05-25 1984-05-14 1-(4'-forgrenet alkylsulfonylphenyl)-6-chlor-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepiner

Country Status (12)

Country Link
US (1) US4514394A (enExample)
EP (1) EP0127423B1 (enExample)
JP (1) JPS59227863A (enExample)
AT (1) ATE32338T1 (enExample)
AU (1) AU572136B2 (enExample)
CA (1) CA1209137A (enExample)
DE (1) DE3469172D1 (enExample)
DK (1) DK238484A (enExample)
ES (1) ES8507500A1 (enExample)
GR (1) GR82033B (enExample)
PT (1) PT78627A (enExample)
ZA (1) ZA843140B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600714A (en) * 1984-04-26 1986-07-15 Smithkline Beckman Corporation Fenoldopam 4',8-bis-hydrogen sulfate and dopaminergic use thereof
US4824839A (en) * 1985-12-20 1989-04-25 Smithkline Beckman Corporation Sulfinyl and sulfonyl substituted 2,3,4,5 tetrahydro-1H-3-benzazepines and their use in treating gastrointestinal motility disorders
US4707483A (en) * 1985-12-20 1987-11-17 Smithkline Beckman Corporation 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders
CN1823059A (zh) 2003-05-22 2006-08-23 先灵公司 作为治疗肥胖和CNS疾病的选择性D<sub>1</sub>/D<sub>5</sub>受体拮抗剂的5－H－苯并[D]萘并[2,1－B]氮杂䓬衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104379A (en) * 1977-01-19 1978-08-01 Smithkline Corporation Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4285938A (en) * 1979-10-11 1981-08-25 Smithkline Corporation 7,8-Dihydroxy-1-(sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives
NZ203064A (en) * 1982-02-24 1985-05-31 Smithkline Beckman Corp R-or s-6-chloro-7,8-dihydroxy-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepine

Also Published As

Publication number Publication date
EP0127423A2 (en) 1984-12-05
PT78627A (en) 1984-06-01
US4514394A (en) 1985-04-30
AU2755684A (en) 1984-12-06
JPS59227863A (ja) 1984-12-21
CA1209137A (en) 1986-08-05
EP0127423A3 (en) 1985-11-06
ES532747A0 (es) 1985-09-01
DE3469172D1 (de) 1988-03-10
ATE32338T1 (de) 1988-02-15
EP0127423B1 (en) 1988-02-03
AU572136B2 (en) 1988-05-05
ZA843140B (en) 1985-02-27
DK238484D0 (da) 1984-05-14
GR82033B (enExample) 1984-12-12
ES8507500A1 (es) 1985-09-01

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