PT78627A - 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepines - Google Patents

1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepines

Info

Publication number
PT78627A
PT78627A PT78627A PT7862784A PT78627A PT 78627 A PT78627 A PT 78627A PT 78627 A PT78627 A PT 78627A PT 7862784 A PT7862784 A PT 7862784A PT 78627 A PT78627 A PT 78627A
Authority
PT
Portugal
Prior art keywords
benzazepines
dihydroxy
chloro
alkylsulfonylphenyl
tetrahydro
Prior art date
Application number
PT78627A
Other languages
English (en)
Portuguese (pt)
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of PT78627A publication Critical patent/PT78627A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Epoxy Compounds (AREA)
PT78627A 1983-05-25 1984-05-22 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepines PT78627A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/498,351 US4514394A (en) 1983-05-25 1983-05-25 Anti-hypertensive use of 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines

Publications (1)

Publication Number Publication Date
PT78627A true PT78627A (en) 1984-06-01

Family

ID=23980717

Family Applications (1)

Application Number Title Priority Date Filing Date
PT78627A PT78627A (en) 1983-05-25 1984-05-22 1-(4'-branched alkylsulfonylphenyl)-6-chloro-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-3-benzazepines

Country Status (12)

Country Link
US (1) US4514394A (enExample)
EP (1) EP0127423B1 (enExample)
JP (1) JPS59227863A (enExample)
AT (1) ATE32338T1 (enExample)
AU (1) AU572136B2 (enExample)
CA (1) CA1209137A (enExample)
DE (1) DE3469172D1 (enExample)
DK (1) DK238484A (enExample)
ES (1) ES8507500A1 (enExample)
GR (1) GR82033B (enExample)
PT (1) PT78627A (enExample)
ZA (1) ZA843140B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4600714A (en) * 1984-04-26 1986-07-15 Smithkline Beckman Corporation Fenoldopam 4',8-bis-hydrogen sulfate and dopaminergic use thereof
US4824839A (en) * 1985-12-20 1989-04-25 Smithkline Beckman Corporation Sulfinyl and sulfonyl substituted 2,3,4,5 tetrahydro-1H-3-benzazepines and their use in treating gastrointestinal motility disorders
US4707483A (en) * 1985-12-20 1987-11-17 Smithkline Beckman Corporation 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders
CN1823059A (zh) 2003-05-22 2006-08-23 先灵公司 作为治疗肥胖和CNS疾病的选择性D<sub>1</sub>/D<sub>5</sub>受体拮抗剂的5－H－苯并[D]萘并[2,1－B]氮杂䓬衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4104379A (en) * 1977-01-19 1978-08-01 Smithkline Corporation Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4285938A (en) * 1979-10-11 1981-08-25 Smithkline Corporation 7,8-Dihydroxy-1-(sulfamylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives
NZ203064A (en) * 1982-02-24 1985-05-31 Smithkline Beckman Corp R-or s-6-chloro-7,8-dihydroxy-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepine

Also Published As

Publication number Publication date
EP0127423A2 (en) 1984-12-05
US4514394A (en) 1985-04-30
AU2755684A (en) 1984-12-06
JPS59227863A (ja) 1984-12-21
CA1209137A (en) 1986-08-05
DK238484A (da) 1984-11-26
EP0127423A3 (en) 1985-11-06
ES532747A0 (es) 1985-09-01
DE3469172D1 (de) 1988-03-10
ATE32338T1 (de) 1988-02-15
EP0127423B1 (en) 1988-02-03
AU572136B2 (en) 1988-05-05
ZA843140B (en) 1985-02-27
DK238484D0 (da) 1984-05-14
GR82033B (enExample) 1984-12-12
ES8507500A1 (es) 1985-09-01

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