DK2352472T3 - Dried and irradiated skin equivalents ready to use - Google Patents
Dried and irradiated skin equivalents ready to use Download PDFInfo
- Publication number
- DK2352472T3 DK2352472T3 DK09825325.5T DK09825325T DK2352472T3 DK 2352472 T3 DK2352472 T3 DK 2352472T3 DK 09825325 T DK09825325 T DK 09825325T DK 2352472 T3 DK2352472 T3 DK 2352472T3
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- DK
- Denmark
- Prior art keywords
- skin equivalent
- tissues
- skin
- cells
- irradiated
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A61F2/105—Skin implants, e.g. artificial skin
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
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- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
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- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
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| US11115308P | 2008-11-04 | 2008-11-04 | |
| PCT/US2009/063217 WO2010053948A1 (en) | 2008-11-04 | 2009-11-04 | Dried and irradiated skin equivalents for ready use |
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| DK2352472T3 true DK2352472T3 (en) | 2017-04-10 |
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| ES (1) | ES2621324T3 (Direct) |
| PT (1) | PT2352472T (Direct) |
| WO (1) | WO2010053948A1 (Direct) |
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| CA2742595C (en) | 2008-11-04 | 2014-04-01 | Stratatech Corporation | Dried and irradiated skin equivalents for ready use |
| US20100330046A1 (en) * | 2009-05-21 | 2010-12-30 | Stratatech Corporation | Human skin substitutes expressing il-12 |
| PT2967836T (pt) | 2013-03-13 | 2019-01-21 | Stratatech Corp | Criopreservação de substitutos de pele humana viáveis |
| KR101701396B1 (ko) | 2014-10-28 | 2017-02-01 | 주식회사 엑티저 | 오디오 신호 처리 장치 및 방법 |
| US20220287298A1 (en) * | 2017-01-27 | 2022-09-15 | Stratatech Corporation | Tissue container systems |
| JP2022549688A (ja) * | 2019-09-27 | 2022-11-28 | ストラタテック コーポレーション | 急性創傷を治療し、転帰を改善するための方法 |
| AU2021271705A1 (en) * | 2020-05-13 | 2022-12-08 | Stratatech Corporation | Viable bioengineered skin constructs |
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| IL95429A (en) * | 1989-09-15 | 1997-09-30 | Organogenesis | Living tissue equivalents comprising hydrated collagen lattice and a collagen gel and their production |
| CA2080693C (en) * | 1990-04-24 | 2001-11-27 | Mark Eisenberg | Composite living skin equivalents |
| US6585969B1 (en) * | 1991-11-20 | 2003-07-01 | N. V. Innogenetics S.A. | Non-viable keratinocyte cell composition or lysate for promoting wound healing |
| DK0615545T3 (da) * | 1991-11-20 | 2000-10-30 | Innogenetics Nv | Lysater hidrørende fra keratinocytter til brug som sårhelingsmidler |
| EP0790767B1 (en) | 1994-11-09 | 2001-10-10 | Celadon Science, LLC | Wound repair dressings and methods for their preservation |
| US5693332C1 (en) * | 1995-08-11 | 2001-01-09 | Univ California | Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure |
| JP3377354B2 (ja) * | 1995-12-25 | 2003-02-17 | 株式会社メニコン | 人工皮膚 |
| US5968546A (en) * | 1997-05-16 | 1999-10-19 | Baur; Marcus | Keratinocyte culture from precursor cells |
| US5989837A (en) * | 1998-07-13 | 1999-11-23 | Wisconsin Alumni Research Foundation | Immortalized human keratinocyte cell line |
| WO2001005942A2 (en) * | 1999-07-20 | 2001-01-25 | Epitech S.A. | Improved keratinocyte culture and uses thereof |
| US6866686B2 (en) * | 2000-01-28 | 2005-03-15 | Cryolife, Inc. | Tissue graft |
| US6974697B2 (en) * | 2001-03-02 | 2005-12-13 | Stratech Corporation | Skin substitutes with improved barrier function |
| JP4317366B2 (ja) * | 2001-03-02 | 2009-08-19 | ストラタテック コーポレーション | 改良代用皮膚およびその使用法 |
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| AU2003254298A1 (en) | 2002-08-02 | 2004-02-23 | Stratatech Corporation | Species specific dna detection |
| US7993922B2 (en) * | 2002-10-18 | 2011-08-09 | Reliance Life Sciences Pvt. Ltd. | Three-dimensional tissue equivalent using macromass culture |
| CA2527822A1 (en) | 2003-05-30 | 2004-12-23 | Stratatech Corporation | Room temperature storage of organs |
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| CA2758178C (en) | 2003-08-01 | 2016-10-11 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| US9526746B2 (en) * | 2004-02-13 | 2016-12-27 | Smith & Nephew, Inc. | Wound healing composition |
| US20060141627A1 (en) * | 2004-11-18 | 2006-06-29 | Stratatech Corporation | Vectors for stable gene expression |
| CA2600177C (en) | 2005-03-01 | 2011-06-14 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| AU2006227752B2 (en) * | 2005-03-17 | 2010-10-21 | Stratatech Corporation | Skin substitutes with improved purity |
| CN100400655C (zh) * | 2005-12-02 | 2008-07-09 | 王平安 | 组织工程化细胞外基质的制备方法 |
| JP5719172B2 (ja) * | 2007-11-14 | 2015-05-13 | ストラタテック コーポレーション | 臨床用途のための器官培養された皮膚同等物の冷蔵保管方法 |
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| US20100330046A1 (en) * | 2009-05-21 | 2010-12-30 | Stratatech Corporation | Human skin substitutes expressing il-12 |
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| EP2352472A4 (en) | 2014-03-05 |
| EP2352472A1 (en) | 2011-08-10 |
| US20100119615A1 (en) | 2010-05-13 |
| JP2012508064A (ja) | 2012-04-05 |
| US9867904B2 (en) | 2018-01-16 |
| US8685463B2 (en) | 2014-04-01 |
| EP2352472B1 (en) | 2017-01-04 |
| JP5632383B2 (ja) | 2014-11-26 |
| JP2014221417A (ja) | 2014-11-27 |
| WO2010053948A1 (en) | 2010-05-14 |
| US9526811B2 (en) | 2016-12-27 |
| US20170087276A1 (en) | 2017-03-30 |
| US20140067064A1 (en) | 2014-03-06 |
| CN102271634A (zh) | 2011-12-07 |
| US20150196686A1 (en) | 2015-07-16 |
| PT2352472T (pt) | 2017-04-11 |
| US20140288165A1 (en) | 2014-09-25 |
| AU2009313656A1 (en) | 2010-05-14 |
| CA2742595C (en) | 2014-04-01 |
| US8580314B2 (en) | 2013-11-12 |
| AU2009313656B2 (en) | 2014-02-20 |
| ES2621324T3 (es) | 2017-07-03 |
| US8992997B2 (en) | 2015-03-31 |
| CA2742595A1 (en) | 2010-05-14 |
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