DK234182A - Fremgangsmaade til fremstilling af heterocyclisk substitueredeamidoximer eller syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af heterocyclisk substitueredeamidoximer eller syreadditionssalte deraf Download PDFInfo
- Publication number
- DK234182A DK234182A DK234182A DK234182A DK234182A DK 234182 A DK234182 A DK 234182A DK 234182 A DK234182 A DK 234182A DK 234182 A DK234182 A DK 234182A DK 234182 A DK234182 A DK 234182A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- acid addition
- addition salts
- heterocyclic substituted
- preparing heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8110428A FR2506767A1 (fr) | 1981-05-26 | 1981-05-26 | Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK234182A true DK234182A (da) | 1982-11-27 |
Family
ID=9258896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK234182A DK234182A (da) | 1981-05-26 | 1982-05-25 | Fremgangsmaade til fremstilling af heterocyclisk substitueredeamidoximer eller syreadditionssalte deraf |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4438121A (ja) |
| EP (1) | EP0067094B1 (ja) |
| JP (1) | JPS57206663A (ja) |
| AR (1) | AR230047A1 (ja) |
| AT (1) | ATE15894T1 (ja) |
| AU (1) | AU550769B2 (ja) |
| CA (1) | CA1185603A (ja) |
| DE (1) | DE3266640D1 (ja) |
| DK (1) | DK234182A (ja) |
| ES (1) | ES8304086A1 (ja) |
| FI (1) | FI821857A0 (ja) |
| FR (1) | FR2506767A1 (ja) |
| GR (1) | GR76445B (ja) |
| HU (1) | HU186515B (ja) |
| IL (1) | IL65876A (ja) |
| NO (1) | NO821725L (ja) |
| NZ (1) | NZ200729A (ja) |
| PT (1) | PT74952B (ja) |
| ZA (1) | ZA823628B (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2506767A1 (fr) * | 1981-05-26 | 1982-12-03 | Synthelabo | Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique |
| FR2564461B1 (fr) * | 1984-05-15 | 1986-09-19 | Synthelabo | Derives d'isoquinoleine, leur preparation et leurs applications |
| TW200643015A (en) * | 2005-03-11 | 2006-12-16 | Akzo Nobel Nv | 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives |
| CN101528703B (zh) * | 2006-09-11 | 2011-09-07 | 欧加农股份有限公司 | 2-（1-氧代-1h-异喹啉-2-基）乙酰胺衍生物 |
| EP2069315B1 (en) * | 2006-09-11 | 2011-09-07 | N.V. Organon | Quinazolinone and isoquinolinone acetamide derivatives |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2425288A (en) * | 1945-01-08 | 1947-08-05 | Commercial Solvents Corp | Plasticized butadiene polymer compositions containing phthalimidoalkyl alkanoates |
| US3291799A (en) | 1964-09-21 | 1966-12-13 | Hoffmann La Roche | Isoquinoline carboxamidine |
| DE1670497C3 (de) | 1967-06-06 | 1973-12-20 | Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt, Budapest | Isochinohnderivate und Verfahren zu deren Herstellung |
| US3635974A (en) * | 1968-12-20 | 1972-01-18 | Boehringer Sohn Ingelheim | Alpha-phenyl-2-aminomethyl-benzylalcohols and salts thereof |
| US3686184A (en) | 1969-04-21 | 1972-08-22 | Sterling Drug Inc | 3,4-dihydro-2(1h)-isoquinolinecarboxamidoximes |
| US3658832A (en) * | 1969-12-08 | 1972-04-25 | American Cyanamid Co | Novel antimicrobial nitroimidazolyl-1 2 4-oxadiazoles |
| US3654299A (en) * | 1969-12-08 | 1972-04-04 | American Cyanamid Co | Nitroimidazolyl antimicrobial agents |
| US3795735A (en) * | 1969-12-08 | 1974-03-05 | American Cyanamid Co | Antimicrobial nitroimidazolyl-1,2,4-oxadiazoles |
| FR2150590A1 (en) * | 1971-08-27 | 1973-04-13 | Ferlux | N (2-phenyl-3-pyridayon-4-yl)piperalines - with analgesic antipyretic antiinflammatory and hypotensive activity |
| BE792182A (fr) * | 1971-12-03 | 1973-06-01 | Hoffmann La Roche | 5-nitro-imidazoles |
| US3927000A (en) | 1972-08-21 | 1975-12-16 | Sterling Drug Inc | 1(OR 3) Perfluoroalkyl-3,4-dihydro-2(1H)-isoquinolinecarbonitriles and intermediates |
| IL44350A0 (en) * | 1973-04-05 | 1974-06-30 | Sparamedica Ag | New imidazole derivatives,their manufacture and pharmaceutical compositions containing them |
| US3984470A (en) | 1974-01-15 | 1976-10-05 | Labaz | Amidoxime derivatives and process for preparing the same |
| FR2257273B1 (ja) | 1974-01-15 | 1978-01-13 | Labaz | |
| GB1477607A (en) | 1975-03-13 | 1977-06-22 | Roche Products Ltd | 2-amidino-4-hydroxy-1,2,3,4-tetrahydroisoquinoline and salts thereof |
| CH623971B5 (de) * | 1976-06-04 | 1982-01-15 | Hoechst Ag | Verfahren zur herstellung neuer benzofuranderivate und deren verwendung als optische aufheller. |
| US4048176A (en) * | 1976-07-23 | 1977-09-13 | Morton-Norwich Products, Inc. | 2-(3-Methyl-4-phenyl-1,2,3,4-tetrahydro-2-isoquinolyl)-acetamidoxime dihydrochloride |
| GB1602110A (en) * | 1977-04-21 | 1981-11-04 | Lafon Labor | Acetamidoxime derivatives |
| US4265911A (en) | 1979-10-09 | 1981-05-05 | Synthelabo | Propionamidoxime derivatives |
| FR2506767A1 (fr) * | 1981-05-26 | 1982-12-03 | Synthelabo | Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique |
-
1981
- 1981-05-26 FR FR8110428A patent/FR2506767A1/fr active Granted
-
1982
- 1982-05-18 DE DE8282400920T patent/DE3266640D1/de not_active Expired
- 1982-05-18 EP EP82400920A patent/EP0067094B1/fr not_active Expired
- 1982-05-18 AT AT82400920T patent/ATE15894T1/de active
- 1982-05-24 AR AR289500A patent/AR230047A1/es active
- 1982-05-25 FI FI821857A patent/FI821857A0/fi not_active Application Discontinuation
- 1982-05-25 NZ NZ200729A patent/NZ200729A/en unknown
- 1982-05-25 HU HU821693A patent/HU186515B/hu unknown
- 1982-05-25 DK DK234182A patent/DK234182A/da not_active Application Discontinuation
- 1982-05-25 IL IL65876A patent/IL65876A/xx unknown
- 1982-05-25 ES ES512520A patent/ES8304086A1/es not_active Expired
- 1982-05-25 US US06/381,749 patent/US4438121A/en not_active Expired - Fee Related
- 1982-05-25 AU AU84157/82A patent/AU550769B2/en not_active Ceased
- 1982-05-25 NO NO821725A patent/NO821725L/no unknown
- 1982-05-25 PT PT74952A patent/PT74952B/pt unknown
- 1982-05-25 GR GR68258A patent/GR76445B/el unknown
- 1982-05-25 ZA ZA823628A patent/ZA823628B/xx unknown
- 1982-05-25 CA CA000403620A patent/CA1185603A/en not_active Expired
- 1982-05-25 JP JP57089610A patent/JPS57206663A/ja active Granted
-
1983
- 1983-10-25 US US06/545,159 patent/US4530843A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2506767A1 (fr) | 1982-12-03 |
| US4530843A (en) | 1985-07-23 |
| HU186515B (en) | 1985-08-28 |
| PT74952A (fr) | 1982-06-01 |
| FR2506767B1 (ja) | 1984-02-10 |
| DE3266640D1 (en) | 1985-11-07 |
| PT74952B (fr) | 1985-05-16 |
| ES512520A0 (es) | 1983-02-16 |
| IL65876A (en) | 1985-09-29 |
| JPS57206663A (en) | 1982-12-18 |
| NZ200729A (en) | 1984-07-31 |
| US4438121A (en) | 1984-03-20 |
| GR76445B (ja) | 1984-08-10 |
| ZA823628B (en) | 1983-03-30 |
| AU550769B2 (en) | 1986-04-10 |
| AR230047A1 (es) | 1984-02-29 |
| NO821725L (no) | 1982-11-29 |
| CA1185603A (en) | 1985-04-16 |
| JPS625423B2 (ja) | 1987-02-04 |
| IL65876A0 (en) | 1982-08-31 |
| ES8304086A1 (es) | 1983-02-16 |
| ATE15894T1 (de) | 1985-10-15 |
| EP0067094B1 (fr) | 1985-10-02 |
| AU8415782A (en) | 1982-12-02 |
| EP0067094A1 (fr) | 1982-12-15 |
| FI821857A0 (fi) | 1982-05-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |