JPS57206663A - Heterocyclic amidoxime derivative - Google Patents

Heterocyclic amidoxime derivative

Info

Publication number
JPS57206663A
JPS57206663A JP57089610A JP8961082A JPS57206663A JP S57206663 A JPS57206663 A JP S57206663A JP 57089610 A JP57089610 A JP 57089610A JP 8961082 A JP8961082 A JP 8961082A JP S57206663 A JPS57206663 A JP S57206663A
Authority
JP
Japan
Prior art keywords
heterocyclic
amidoxime derivative
amidoxime
derivative
heterocyclic amidoxime
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57089610A
Other languages
English (en)
Other versions
JPS625423B2 (ja
Inventor
Danieru Obitsutsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SANTERABO SA
Synthelabo SA
Original Assignee
SANTERABO SA
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SANTERABO SA, Synthelabo SA filed Critical SANTERABO SA
Publication of JPS57206663A publication Critical patent/JPS57206663A/ja
Publication of JPS625423B2 publication Critical patent/JPS625423B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP57089610A 1981-05-26 1982-05-25 Heterocyclic amidoxime derivative Granted JPS57206663A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8110428A FR2506767A1 (fr) 1981-05-26 1981-05-26 Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
JPS57206663A true JPS57206663A (en) 1982-12-18
JPS625423B2 JPS625423B2 (ja) 1987-02-04

Family

ID=9258896

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57089610A Granted JPS57206663A (en) 1981-05-26 1982-05-25 Heterocyclic amidoxime derivative

Country Status (19)

Country Link
US (2) US4438121A (ja)
EP (1) EP0067094B1 (ja)
JP (1) JPS57206663A (ja)
AR (1) AR230047A1 (ja)
AT (1) ATE15894T1 (ja)
AU (1) AU550769B2 (ja)
CA (1) CA1185603A (ja)
DE (1) DE3266640D1 (ja)
DK (1) DK234182A (ja)
ES (1) ES8304086A1 (ja)
FI (1) FI821857A0 (ja)
FR (1) FR2506767A1 (ja)
GR (1) GR76445B (ja)
HU (1) HU186515B (ja)
IL (1) IL65876A (ja)
NO (1) NO821725L (ja)
NZ (1) NZ200729A (ja)
PT (1) PT74952B (ja)
ZA (1) ZA823628B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2506767A1 (fr) * 1981-05-26 1982-12-03 Synthelabo Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique
FR2564461B1 (fr) * 1984-05-15 1986-09-19 Synthelabo Derives d'isoquinoleine, leur preparation et leurs applications
TW200643015A (en) * 2005-03-11 2006-12-16 Akzo Nobel Nv 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
CA2663161C (en) * 2006-09-11 2014-10-28 N.V. Organon Quinazolinone and isoquinolinone acetamide derivatives
CN101528703B (zh) * 2006-09-11 2011-09-07 欧加农股份有限公司 2-（1-氧代-1h-异喹啉-2-基）乙酰胺衍生物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2425288A (en) * 1945-01-08 1947-08-05 Commercial Solvents Corp Plasticized butadiene polymer compositions containing phthalimidoalkyl alkanoates
US3291799A (en) 1964-09-21 1966-12-13 Hoffmann La Roche Isoquinoline carboxamidine
DE1670497C3 (de) 1967-06-06 1973-12-20 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt, Budapest Isochinohnderivate und Verfahren zu deren Herstellung
US3635974A (en) * 1968-12-20 1972-01-18 Boehringer Sohn Ingelheim Alpha-phenyl-2-aminomethyl-benzylalcohols and salts thereof
US3686184A (en) 1969-04-21 1972-08-22 Sterling Drug Inc 3,4-dihydro-2(1h)-isoquinolinecarboxamidoximes
US3795735A (en) * 1969-12-08 1974-03-05 American Cyanamid Co Antimicrobial nitroimidazolyl-1,2,4-oxadiazoles
US3654299A (en) * 1969-12-08 1972-04-04 American Cyanamid Co Nitroimidazolyl antimicrobial agents
US3658832A (en) * 1969-12-08 1972-04-25 American Cyanamid Co Novel antimicrobial nitroimidazolyl-1 2 4-oxadiazoles
FR2150590A1 (en) * 1971-08-27 1973-04-13 Ferlux N (2-phenyl-3-pyridayon-4-yl)piperalines - with analgesic antipyretic antiinflammatory and hypotensive activity
BE792182A (fr) * 1971-12-03 1973-06-01 Hoffmann La Roche 5-nitro-imidazoles
US3927000A (en) 1972-08-21 1975-12-16 Sterling Drug Inc 1(OR 3) Perfluoroalkyl-3,4-dihydro-2(1H)-isoquinolinecarbonitriles and intermediates
IL44350A0 (en) * 1973-04-05 1974-06-30 Sparamedica Ag New imidazole derivatives,their manufacture and pharmaceutical compositions containing them
US3984470A (en) 1974-01-15 1976-10-05 Labaz Amidoxime derivatives and process for preparing the same
FR2257273B1 (ja) 1974-01-15 1978-01-13 Labaz
GB1477607A (en) 1975-03-13 1977-06-22 Roche Products Ltd 2-amidino-4-hydroxy-1,2,3,4-tetrahydroisoquinoline and salts thereof
CH623971B5 (de) * 1976-06-04 1982-01-15 Hoechst Ag Verfahren zur herstellung neuer benzofuranderivate und deren verwendung als optische aufheller.
US4048176A (en) * 1976-07-23 1977-09-13 Morton-Norwich Products, Inc. 2-(3-Methyl-4-phenyl-1,2,3,4-tetrahydro-2-isoquinolyl)-acetamidoxime dihydrochloride
GB1602110A (en) * 1977-04-21 1981-11-04 Lafon Labor Acetamidoxime derivatives
US4265911A (en) 1979-10-09 1981-05-05 Synthelabo Propionamidoxime derivatives
FR2506767A1 (fr) * 1981-05-26 1982-12-03 Synthelabo Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS *

Also Published As

Publication number Publication date
CA1185603A (en) 1985-04-16
FR2506767A1 (fr) 1982-12-03
ES512520A0 (es) 1983-02-16
PT74952A (fr) 1982-06-01
US4438121A (en) 1984-03-20
DK234182A (da) 1982-11-27
IL65876A0 (en) 1982-08-31
FR2506767B1 (ja) 1984-02-10
NZ200729A (en) 1984-07-31
NO821725L (no) 1982-11-29
ATE15894T1 (de) 1985-10-15
EP0067094B1 (fr) 1985-10-02
DE3266640D1 (en) 1985-11-07
ZA823628B (en) 1983-03-30
FI821857A0 (fi) 1982-05-25
GR76445B (ja) 1984-08-10
HU186515B (en) 1985-08-28
PT74952B (fr) 1985-05-16
AU550769B2 (en) 1986-04-10
AR230047A1 (es) 1984-02-29
EP0067094A1 (fr) 1982-12-15
JPS625423B2 (ja) 1987-02-04
US4530843A (en) 1985-07-23
IL65876A (en) 1985-09-29
AU8415782A (en) 1982-12-02
ES8304086A1 (es) 1983-02-16

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