DK2320933T3 - THERAPEUTIC DOSAGE OF A NEUREGULIN OR A SUBSEQUENT THEREOF FOR TREATMENT OR PROPHYLAXY OF HEART FAILURE - Google Patents
THERAPEUTIC DOSAGE OF A NEUREGULIN OR A SUBSEQUENT THEREOF FOR TREATMENT OR PROPHYLAXY OF HEART FAILURE Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
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- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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US13517108P | 2008-07-17 | 2008-07-17 | |
PCT/US2009/004130 WO2010030317A2 (en) | 2008-07-17 | 2009-07-17 | Therapeutic dosing of a neuregulin or a subsequence thereof for treatment or prophylaxis of heart failure |
Publications (1)
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DK2320933T3 true DK2320933T3 (en) | 2018-04-16 |
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DK09813336.6T DK2320933T3 (en) | 2008-07-17 | 2009-07-17 | THERAPEUTIC DOSAGE OF A NEUREGULIN OR A SUBSEQUENT THEREOF FOR TREATMENT OR PROPHYLAXY OF HEART FAILURE |
DK17209369.2T DK3338791T3 (da) | 2008-07-17 | 2009-07-17 | Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt |
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Application Number | Title | Priority Date | Filing Date |
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DK17209369.2T DK3338791T3 (da) | 2008-07-17 | 2009-07-17 | Terapeutisk dosering af en neuregulin i behandling eller profylaxis af hjertesvigt |
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US (5) | US20110166068A1 (lt) |
EP (3) | EP3632459A1 (lt) |
JP (5) | JP5797112B2 (lt) |
CN (3) | CN104623633A (lt) |
AU (3) | AU2009292216B2 (lt) |
BR (1) | BRPI0916442A2 (lt) |
CA (1) | CA2731113A1 (lt) |
DK (2) | DK2320933T3 (lt) |
ES (2) | ES2763184T3 (lt) |
HK (1) | HK1256637A1 (lt) |
MX (1) | MX2011000696A (lt) |
PL (2) | PL2320933T3 (lt) |
RU (4) | RU2536938C2 (lt) |
WO (1) | WO2010030317A2 (lt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
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DK2320933T3 (en) * | 2008-07-17 | 2018-04-16 | Acorda Therapeutics Inc | THERAPEUTIC DOSAGE OF A NEUREGULIN OR A SUBSEQUENT THEREOF FOR TREATMENT OR PROPHYLAXY OF HEART FAILURE |
CN104707130A (zh) | 2008-08-15 | 2015-06-17 | 阿索尔达治疗公司 | 在cns神经性损伤后非-急性期间处理的组合物及方法 |
EP2370458B1 (en) * | 2008-11-28 | 2014-10-15 | Zensun (Shanghai) Science and Technology Limited | Neuregulin peptides and their use |
EP3235504B1 (en) | 2009-10-14 | 2019-09-18 | Acorda Therapeutics, Inc. | Use of a neuregulin to treat peripheral nerve injury |
WO2013053076A1 (en) * | 2011-10-10 | 2013-04-18 | Zensun (Shanghai)Science & Technology Limited | Compositions and methods for treating heart failure |
JP6420233B2 (ja) * | 2012-03-30 | 2018-11-07 | アコーダ セラピューティクス,インコーポレーテッド | 末梢神経損傷を処置するためのニューレグリンの使用 |
IL281376B (en) * | 2013-03-06 | 2022-08-01 | Acorda Therapeutics Inc | Medicinal peptides of neuregulin for the treatment or prevention of heart failure |
KR102357275B1 (ko) | 2013-05-22 | 2022-02-03 | 젠순 (상하이) 사이언스 앤드 테크놀로지 캄파니 리미티드 | 심부전을 치료하기 위한 뉴레귤린의 연장 방출 |
CN104758922A (zh) | 2014-01-03 | 2015-07-08 | 上海泽生科技开发有限公司 | 纽兰格林制剂的配方 |
CN111407882A (zh) * | 2014-10-17 | 2020-07-14 | 上海泽生科技开发股份有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
JP7181084B2 (ja) | 2015-09-25 | 2022-11-30 | ダグラス ビー. ソーヤー, | 心臓傷害を処置するための方法 |
US11426447B2 (en) * | 2016-04-19 | 2022-08-30 | Leibniz-Institut Fur Alternsforschung—Fritz-Lipmann-Institut E.V. (Fli) | Neuregulin for the treatment of tumors of the nervous system |
CN110835368A (zh) * | 2018-08-15 | 2020-02-25 | 上海泽生科技开发股份有限公司 | 神经调节蛋白多肽片段及其用途 |
AR121035A1 (es) | 2019-04-01 | 2022-04-13 | Lilly Co Eli | Compuestos de neuregulina-4 y métodos de uso |
EP4032901A4 (en) * | 2019-09-16 | 2023-10-25 | Zensun (Shanghai) Science & Technology, Co., Ltd. | RECOMBINANT HUMAN NEUREGULIN DERIVATIVES AND THEIR USE |
WO2023070078A1 (en) * | 2021-10-22 | 2023-04-27 | The Research Institute At Nationwide Children's Hospital | Neuregulin for protection against respiratory viral infection and post-viral disease |
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US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
US7115554B1 (en) * | 1993-05-06 | 2006-10-03 | Acorda Therapeutics, Inc. | Methods of increasing myotube formation or survival or muscle cell mitogenesis differentiation or survival using neuregulin GGF III |
US6087323A (en) | 1992-04-03 | 2000-07-11 | Cambridge Neuroscience, Inc. | Use of neuregulins as modulators of cellular communication |
US7037888B1 (en) | 1992-04-03 | 2006-05-02 | Acorda Therapeutics, Inc. | Methods for treating muscle diseases and disorders |
US5811098A (en) * | 1992-11-24 | 1998-09-22 | Bristol-Myers Squibb Company | Antibodies to HER4, human receptor tyrosine kinase |
US5912326A (en) | 1995-09-08 | 1999-06-15 | President And Fellows Of Harvard College | Cerebellum-derived growth factors |
US6136558A (en) * | 1997-02-10 | 2000-10-24 | Genentech, Inc. | Heregulin variants |
US6051401A (en) | 1998-07-28 | 2000-04-18 | Bayer Corporation | Methods and constructs for protein expression |
HU230656B1 (hu) | 1998-09-25 | 2017-06-28 | Cubist Pharmaceuticals Llc | Daptomicin alkalmazása |
AUPP785098A0 (en) * | 1998-12-21 | 1999-01-21 | Victor Chang Cardiac Research Institute, The | Treatment of heart disease |
US6635249B1 (en) * | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
CN1138785C (zh) * | 1999-06-04 | 2004-02-18 | 周明东 | 生长因子神经调节蛋白及其类似物的新应用 |
JP2003527337A (ja) | 1999-11-12 | 2003-09-16 | エントレメッド インコーポレイテッド | 抗血管新生スケジュールに基づく治療薬の投与方法 |
US6890751B2 (en) | 2000-05-23 | 2005-05-10 | Acorda Therapeutics, Inc. | NRG-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods |
CU23157A1 (es) * | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
EP1569689A4 (en) | 2002-01-18 | 2009-08-05 | Novartis Vaccines & Diagnostic | THERAPY COMBINED WITH IL-2 AND ANTI-HER2 ANTIBODIES FOR CANCERS CHARACTERIZED BY OVEREXPRESSION OF HER2 RECEPTOR PROTEIN |
AU2002304965A1 (en) | 2002-05-24 | 2003-12-12 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
CA2596768A1 (en) * | 2005-02-18 | 2006-08-24 | Orion Corporation | A method for treating heart failure |
KR20070108259A (ko) | 2005-03-23 | 2007-11-08 | 화이자 프로덕츠 인크. | Ctla-4 항체와 호르몬 요법에 의한 전립선암의 치료법 |
WO2007028085A2 (en) | 2005-09-02 | 2007-03-08 | Morehouse School Of Medicine | Neuregulin for prevention and treatment of damage from acute assault on vascular and neuronal tissues |
US20070213264A1 (en) * | 2005-12-02 | 2007-09-13 | Mingdong Zhou | Neuregulin variants and methods of screening and using thereof |
EP1981525B1 (en) * | 2005-12-30 | 2015-01-21 | Zensun (Shanghai) Science and Technology Limited | Extended release of neuregulin for improved cardiac function |
CA2717193C (en) | 2008-02-29 | 2022-08-16 | Acorda Therapeutics, Inc. | Method for achieving desired glial growth factor 2 plasma levels |
DK2320933T3 (en) | 2008-07-17 | 2018-04-16 | Acorda Therapeutics Inc | THERAPEUTIC DOSAGE OF A NEUREGULIN OR A SUBSEQUENT THEREOF FOR TREATMENT OR PROPHYLAXY OF HEART FAILURE |
EP3235504B1 (en) | 2009-10-14 | 2019-09-18 | Acorda Therapeutics, Inc. | Use of a neuregulin to treat peripheral nerve injury |
CA2845198A1 (en) | 2010-08-13 | 2012-02-16 | Georgetown University | Ggf2 and methods of use |
JP6420233B2 (ja) | 2012-03-30 | 2018-11-07 | アコーダ セラピューティクス,インコーポレーテッド | 末梢神経損傷を処置するためのニューレグリンの使用 |
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2009
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2013
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2017
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2018
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2019
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