DK230789D0 - Fremgangsmaade til fremstilling af cytidinderivater - Google Patents

Fremgangsmaade til fremstilling af cytidinderivater

Info

Publication number
DK230789D0
DK230789D0 DK230789A DK230789A DK230789D0 DK 230789 D0 DK230789 D0 DK 230789D0 DK 230789 A DK230789 A DK 230789A DK 230789 A DK230789 A DK 230789A DK 230789 D0 DK230789 D0 DK 230789D0
Authority
DK
Denmark
Prior art keywords
procedure
preparation
cytidine derivatives
cytidine
derivatives
Prior art date
Application number
DK230789A
Other languages
English (en)
Other versions
DK230789A (da
Inventor
Peter Stefan Belica
Tai-Nang Huang
Percy Sarwood Manchand
John Joseph Partridge
Steve Tam
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK230789D0 publication Critical patent/DK230789D0/da
Publication of DK230789A publication Critical patent/DK230789A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK230789A 1988-05-12 1989-05-11 Fremgangsmaade til fremstilling af cytidinderivater DK230789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/192,978 US4900828A (en) 1988-05-12 1988-05-12 Intermediate compounds and an improved procedure for the synthesis of 2',3'-dideoxycytidine

Publications (2)

Publication Number Publication Date
DK230789D0 true DK230789D0 (da) 1989-05-11
DK230789A DK230789A (da) 1989-11-13

Family

ID=22711809

Family Applications (1)

Application Number Title Priority Date Filing Date
DK230789A DK230789A (da) 1988-05-12 1989-05-11 Fremgangsmaade til fremstilling af cytidinderivater

Country Status (7)

Country Link
US (1) US4900828A (da)
EP (1) EP0341704A3 (da)
JP (1) JPH01319497A (da)
AU (1) AU621615B2 (da)
DK (1) DK230789A (da)
NZ (1) NZ229040A (da)
ZA (1) ZA893436B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290927A (en) * 1988-03-01 1994-03-01 Ajinomoto Co., Inc. Process for preparing 2',3'-dideoxyadenosine
US6069252A (en) * 1990-02-01 2000-05-30 Emory University Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers
US5276151A (en) * 1990-02-01 1994-01-04 Emory University Method of synthesis of 1,3-dioxolane nucleosides
US6703396B1 (en) 1990-02-01 2004-03-09 Emory University Method of resolution and antiviral activity of 1,3-oxathiolane nuclesoside enantiomers
US6642245B1 (en) 1990-02-01 2003-11-04 Emory University Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
US5204466A (en) * 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
AU7558491A (en) * 1990-04-04 1991-10-30 Nycomed Imaging As Nucleoside derivatives
JPH0592970A (ja) * 1991-03-01 1993-04-16 Bristol Myers Squibb Co ヌクレオシド誘導体の合成法
DE4110977A1 (de) * 1991-04-05 1992-10-08 Bayer Ag Substituierte 2',3'-didesoxy-5-trifluormethyluridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
US5817667A (en) * 1991-04-17 1998-10-06 University Of Georgia Research Foudation Compounds and methods for the treatment of cancer
US5192764A (en) * 1991-05-30 1993-03-09 Research Foundation Of State Of N.Y. Pyrazinone n-oxide nucleosides and analogs thereof
WO1993006119A1 (en) * 1991-09-27 1993-04-01 The Institute Of Cancer Research Deoxynucleoside derivatives
RU2085557C1 (ru) * 1991-09-30 1997-07-27 Санкио Компани Лимитед Производные нуклеозидов пиримидина или их фармацевтически приемлемые соли и способ их получения
CA2171550C (en) * 1993-09-10 2008-08-26 Raymond F. Schinazi Nucleosides with anti-hepatitis b virus activity
US20020120130A1 (en) * 1993-09-10 2002-08-29 Gilles Gosselin 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents
US5587362A (en) * 1994-01-28 1996-12-24 Univ. Of Ga Research Foundation L-nucleosides
IL115156A (en) * 1994-09-06 2000-07-16 Univ Georgia Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines
US5703058A (en) * 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5808040A (en) * 1995-01-30 1998-09-15 Yale University L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides
ES2276404T3 (es) * 1995-06-07 2007-06-16 Emory University Nucleosidos con actividad antivirus de la hepatitis-b.
US5753789A (en) * 1996-07-26 1998-05-19 Yale University Oligonucleotides containing L-nucleosides
US6436948B1 (en) 2000-03-03 2002-08-20 University Of Georgia Research Foundation Inc. Method for the treatment of psoriasis and genital warts
WO2002070533A2 (en) * 2001-03-01 2002-09-12 Pharmasset Ltd. Method for the synthesis of 2',3'-dideoxy-2',3'-didehydronucleosides
CN1297565C (zh) * 2004-03-15 2007-01-31 陆锦康 2′,3′－双脱氧胞苷的生产方法
WO2013036846A2 (en) * 2011-09-09 2013-03-14 Koronis Pharmaceuticals, Incorporated N4 derivatives of deoxycytidine prodrugs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604382A (en) * 1983-01-17 1986-08-05 Research Corporation 3'-amino-2',3'-dideoxycytidine and the pharmacologically acceptable salts thereof

Also Published As

Publication number Publication date
EP0341704A3 (de) 1990-12-05
EP0341704A2 (de) 1989-11-15
AU621615B2 (en) 1992-03-19
DK230789A (da) 1989-11-13
NZ229040A (en) 1992-04-28
US4900828A (en) 1990-02-13
AU3468689A (en) 1989-11-16
ZA893436B (en) 1990-01-31
JPH01319497A (ja) 1989-12-25

Similar Documents

Publication Publication Date Title
DK230789D0 (da) Fremgangsmaade til fremstilling af cytidinderivater
DK404187D0 (da) Fremgangsmaade til fremstilling af thiazolderivater
DK612789D0 (da) Fremgangsmaade til fremstilling af pyridinderivater
DK250689A (da) Fremgangsmaade til fremstilling af napthalenderivater
DK165984C (da) Fremgangsmaade til fremstilling af sphingosinderivater
DK30489A (da) Fremgangsmaade til fremstilling af pyranderivater
DK516286A (da) Fremgangsmaade til fremstilling af oxazolderivater
DK164988D0 (da) Fremgangsmaade til fremstilling af chromanderivater
DK100289A (da) Fremgangsmaade til fremstilling af n-sulfonylurinstoffer
DK601489A (da) Fremgangsmaade til fremstilling af alkansulfonamider
DK314988A (da) Fremgangsmaade til fremstilling af 6-deoxyguaninderivater
DK315789A (da) Fremgangsmaade til fremstilling af halogenerede sulfoner
DK455889D0 (da) Fremgangsmaade til fremstilling af kulhydratderivater
DK113189A (da) Fremgangsmaade til fremstilling af pyridinderivater
DK143889A (da) Fremgangsmaade til fremstilling af naphthalenderivater
DK293589D0 (da) Fremgangsmaade til fremstiling af lactolderivater
DK184789A (da) Fremgangsmaade til fremstilling af naphthalenderivater
DK599689A (da) Fremgangsmaade til fremstilling af naphthalenderivater
DK732088A (da) Fremgangsmaade til fremstilling af 1,5-benzothiazepinderivater
DK631888D0 (da) Fremgangsmaade til fremstilling af 1,5-benzothiazepinderivater
DK326789D0 (da) Fremstilling af homonojirimycin-derivater
DK162789D0 (da) Fremgangsmaade til fremstilling af alkalimetalphenylpyruvat
DK291785A (da) Fremgangsmaade til fremstilling af iminderivater
DK26888A (da) Fremgangmsaade til fremstilling af diaminoalkanderivater
DK256786D0 (da) Fremgangsmaade til fremstilling af triazolderivater

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment