DK229476A - Prostanderivater og fremgangsmade til fremstilling deraf - Google Patents

Prostanderivater og fremgangsmade til fremstilling deraf

Info

Publication number
DK229476A
DK229476A DK229476A DK229476A DK229476A DK 229476 A DK229476 A DK 229476A DK 229476 A DK229476 A DK 229476A DK 229476 A DK229476 A DK 229476A DK 229476 A DK229476 A DK 229476A
Authority
DK
Denmark
Prior art keywords
prostand
procedures
derivatives
manufacture
prostand derivatives
Prior art date
Application number
DK229476A
Other languages
Danish (da)
English (en)
Inventor
W Skuballa
B Radychel
H Vorbryggen
W Elger
O Loge
E Schillinger
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752523676 external-priority patent/DE2523676A1/de
Priority claimed from DE19762616304 external-priority patent/DE2616304A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK229476A publication Critical patent/DK229476A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK229476A 1975-05-26 1976-05-25 Prostanderivater og fremgangsmade til fremstilling deraf DK229476A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19752523676 DE2523676A1 (de) 1975-05-26 1975-05-26 Neue prostanderivate und verfahren zu ihrer herstellung
DE19762616304 DE2616304A1 (de) 1976-04-12 1976-04-12 Neue prostansaeurederivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DK229476A true DK229476A (da) 1976-11-27

Family

ID=25768952

Family Applications (1)

Application Number Title Priority Date Filing Date
DK229476A DK229476A (da) 1975-05-26 1976-05-25 Prostanderivater og fremgangsmade til fremstilling deraf

Country Status (14)

Country Link
US (2) US4105792A (fr)
JP (1) JPS51143643A (fr)
AT (1) AT359657B (fr)
AU (1) AU510695B2 (fr)
CA (1) CA1091226A (fr)
CH (1) CH623036A5 (fr)
DK (1) DK229476A (fr)
FR (1) FR2312240A1 (fr)
GB (1) GB1553710A (fr)
HU (1) HU177906B (fr)
IE (1) IE44255B1 (fr)
LU (1) LU75011A1 (fr)
NL (1) NL7605381A (fr)
SE (1) SE7605925L (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058564A (en) * 1976-07-26 1977-11-15 The Upjohn Company Aliphatic 2-decarboxy-2-hydroxymethyl-13,14-didehydro-PG compounds
US4149006A (en) * 1977-01-24 1979-04-10 G. D. Searle & Co. Prostaglandin derivatives having alkynyl, hydroxy and aryloxy junctions in the 2β side chain
US4171331A (en) * 1978-06-05 1979-10-16 Miles Laboratories, Inc. 1 And 2-substituted analogues of certain prostaglandins
DE3405181A1 (de) * 1984-02-10 1985-08-22 Schering AG, 1000 Berlin und 4709 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5238961A (en) * 1990-06-14 1993-08-24 Allergan, Inc. Pgf 1-alcohols and their use as ocular hypotensives
US5139491A (en) * 1990-12-06 1992-08-18 Allergan, Inc. 2-decarboxyl-2-alkoxyalkyl prostaglandins as ocular hypotensives
US5767154A (en) * 1991-02-07 1998-06-16 Allergan 5-trans-prostaglandins of the F series and their use as ocular hypotensives
WO1992013836A1 (fr) * 1991-02-07 1992-08-20 Allergan, Inc. Derives 2-decarboxyl-2-hydroxyalkyle de 5-trans-prostaglandines f
US5312832A (en) * 1991-05-17 1994-05-17 Allergan, Inc. Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives
US5688819A (en) * 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5834498A (en) * 1992-09-21 1998-11-10 Allergan Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US5972991A (en) 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5385945A (en) * 1992-10-21 1995-01-31 Allergan, Inc. 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds
US5510383A (en) * 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US6184250B1 (en) * 1993-08-03 2001-02-06 Alcon Laboratories, Inc. Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
US5721273A (en) 1993-12-15 1998-02-24 Alcon Laboratories, Inc. Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension
US5545665A (en) * 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
WO2010102078A1 (fr) 2009-03-04 2010-09-10 Allergan, Inc. Solution ophtalmique améliorée à base de bimatoprost
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3069322A (en) * 1958-05-28 1962-12-18 Bergstrom Sune Pge and pgf
US3723528A (en) * 1967-10-09 1973-03-27 Upjohn Co Prostaglandin oximes and oxime ethers
US3922293A (en) * 1971-12-30 1975-11-25 Upjohn Co Prostaglandin F-type 9-monoacylates
GB1451798A (en) * 1973-08-02 1976-10-06 Ici Ltd Prostanoic acid derivatives
GB1468830A (en) * 1974-01-26 1977-03-30 May & Baker Ltd Cyclopentane derivatives
US3970685A (en) * 1974-06-05 1976-07-20 Syntex (U.S.A.) Inc. (DL)-13-Substituted sulfinyl-prostaglandin-like compounds
US4117119A (en) * 1975-03-11 1978-09-26 Ono Pharmaceutical Company 15-cyclobutyl-prostaglandins

Also Published As

Publication number Publication date
NL7605381A (nl) 1976-11-30
IE44255L (en) 1976-11-26
US4105792A (en) 1978-08-08
LU75011A1 (fr) 1977-01-20
FR2312240B1 (fr) 1979-09-21
AT359657B (de) 1980-11-25
FR2312240A1 (fr) 1976-12-24
HU177906B (en) 1982-01-28
AU510695B2 (en) 1980-07-10
CH623036A5 (fr) 1981-05-15
GB1553710A (en) 1979-09-26
SE7605925L (sv) 1976-11-27
ATA373376A (de) 1980-04-15
US4256745A (en) 1981-03-17
AU1422576A (en) 1977-12-01
JPS51143643A (en) 1976-12-10
CA1091226A (fr) 1980-12-09
IE44255B1 (en) 1981-09-23

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