DK227985A - Kloning og karakterisering af det humane interleukin 1 gen - Google Patents

Kloning og karakterisering af det humane interleukin 1 gen Download PDF

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Publication number
DK227985A
DK227985A DK227985A DK227985A DK227985A DK 227985 A DK227985 A DK 227985A DK 227985 A DK227985 A DK 227985A DK 227985 A DK227985 A DK 227985A DK 227985 A DK227985 A DK 227985A
Authority
DK
Denmark
Prior art keywords
gen
cloning
characterization
human interleukin
interleukin
Prior art date
Application number
DK227985A
Other languages
Danish (da)
English (en)
Other versions
DK227985D0 (da
Inventor
D P Cerretti
Iii P J Conlon
D J Crosman
K H Grabstein
T P Hopp
S R Kronheim
A D Larsen
C J March
B A Mosley
V L Price
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of DK227985D0 publication Critical patent/DK227985D0/da
Publication of DK227985A publication Critical patent/DK227985A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK227985A 1985-01-17 1985-05-22 Kloning og karakterisering af det humane interleukin 1 gen DK227985A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69241685A 1985-01-17 1985-01-17
US72176585A 1985-04-10 1985-04-10

Publications (2)

Publication Number Publication Date
DK227985D0 DK227985D0 (da) 1985-05-22
DK227985A true DK227985A (da) 1986-07-18

Family

ID=27104963

Family Applications (1)

Application Number Title Priority Date Filing Date
DK227985A DK227985A (da) 1985-01-17 1985-05-22 Kloning og karakterisering af det humane interleukin 1 gen

Country Status (6)

Country Link
EP (1) EP0188864B1 (de)
JP (1) JPH064674B2 (de)
AU (1) AU577856B2 (de)
DE (1) DE3584883D1 (de)
DK (1) DK227985A (de)
NZ (1) NZ212173A (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998578A (en) * 1984-05-18 1999-12-07 New England Medical Center Hospitals, Inc. Biologically active fragments of IL-1β
EP0569687B1 (de) * 1984-05-18 2002-08-21 New England Medical Center Hospitals, Inc. Menschliche IL-1 cDNS-Sequenzen die für biologisch aktive menschliche IL-1-Proteine kodieren
DE3588241T2 (de) * 1984-05-18 2002-12-05 Massachusetts Institute Of Technology, Cambridge Menschliche IL-1 cDNS-Sequenzen die für biologisch aktive menschliche IL-1-Proteine kodieren
CA1340978C (en) * 1984-06-19 2000-05-02 Douglas P. Cerretti Purification, cloning and characterization of the gene for interleukin 1
US6107465A (en) * 1984-12-21 2000-08-22 Otsuka Pharmaceutical Co., Ltd. IL-1β and derivatives thereof and drugs
DK172052B1 (da) * 1984-12-21 1997-09-29 Otsuka Pharma Co Ltd Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor
US5342614A (en) * 1984-12-21 1994-08-30 Otsuka Pharmaceutical Co., Ltd. Method of treating arthritus or inflammation with IL-1β or derivatives thereof
EP0188920B1 (de) * 1984-12-25 1993-09-29 Dainippon Pharmaceutical Co., Ltd. Interleukin-1 und dessen Derivat
DE3683186D1 (de) * 1985-04-25 1992-02-13 Hoffmann La Roche Rekombinantes humaninterleukin-1.
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
EP0644203A1 (de) * 1988-07-29 1995-03-22 Otsuka Pharmaceutical Co., Ltd. IL-1 alpha Derivate und Arzneimittel gegen Thrombozytopenie
US5811523A (en) 1988-11-10 1998-09-22 Trinchieri; Giorgio Antibodies to natural killer stimulatory factor
WO1990012877A1 (en) * 1989-04-19 1990-11-01 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
DE69230862T2 (de) * 1991-10-15 2000-12-14 Michael F. Mullarkey Rezeptoren zur Behandlung von Entzündungen vom verzögerten Typ

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU579089B2 (en) * 1983-02-08 1988-11-17 Biogen, Inc. Human interleukin-2-like polypeptides
NZ212312A (en) * 1984-06-07 1988-09-29 John Richard Murphy Hybrid protein comprising fragments of diphtheria toxin and part of cell-specific ligand; and fused gene therefor
CA1340978C (en) * 1984-06-19 2000-05-02 Douglas P. Cerretti Purification, cloning and characterization of the gene for interleukin 1
JP2579747B2 (ja) * 1984-12-25 1997-02-12 大日本製薬株式会社 ヒトインタ−ロイキン１をコ−ドする新規ｄｎａ
EP0188920B1 (de) * 1984-12-25 1993-09-29 Dainippon Pharmaceutical Co., Ltd. Interleukin-1 und dessen Derivat

Also Published As

Publication number Publication date
JPS61170395A (ja) 1986-08-01
DK227985D0 (da) 1985-05-22
EP0188864A1 (de) 1986-07-30
AU577856B2 (en) 1988-10-06
JPH064674B2 (ja) 1994-01-19
NZ212173A (en) 1988-02-29
AU4265985A (en) 1986-07-24
EP0188864B1 (de) 1991-12-11
DE3584883D1 (de) 1992-01-23

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