DK227689A - Fremgangsmaade til fremstilling af 2-(2-thienyl)-ethylamin og dennes anvendelse til fremstilling af thieno(3,2-c)pyridinderivater - Google Patents

Fremgangsmaade til fremstilling af 2-(2-thienyl)-ethylamin og dennes anvendelse til fremstilling af thieno(3,2-c)pyridinderivater Download PDF

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Publication number
DK227689A
DK227689A DK227689A DK227689A DK227689A DK 227689 A DK227689 A DK 227689A DK 227689 A DK227689 A DK 227689A DK 227689 A DK227689 A DK 227689A DK 227689 A DK227689 A DK 227689A
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Denmark
Prior art keywords
thieno
ethylamine
thienyl
preparing
preparation
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DK227689A
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English (en)
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DK227689D0 (da
Inventor
Eric Lodewijk
Hiralal N Khatri
Original Assignee
Sanofi Sa
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Application filed by Sanofi Sa filed Critical Sanofi Sa
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
DK227689A 1988-05-10 1989-05-09 Fremgangsmaade til fremstilling af 2-(2-thienyl)-ethylamin og dennes anvendelse til fremstilling af thieno(3,2-c)pyridinderivater DK227689A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/192,274 US4906756A (en) 1988-05-10 1988-05-10 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives

Publications (2)

Publication Number Publication Date
DK227689D0 DK227689D0 (da) 1989-05-09
DK227689A true DK227689A (da) 1989-11-11

Family

ID=22708999

Family Applications (1)

Application Number Title Priority Date Filing Date
DK227689A DK227689A (da) 1988-05-10 1989-05-09 Fremgangsmaade til fremstilling af 2-(2-thienyl)-ethylamin og dennes anvendelse til fremstilling af thieno(3,2-c)pyridinderivater

Country Status (8)

Country Link
US (1) US4906756A (da)
EP (1) EP0342118A1 (da)
JP (1) JPH01319485A (da)
KR (1) KR970009227B1 (da)
AU (1) AU626861B2 (da)
DK (1) DK227689A (da)
NZ (1) NZ229046A (da)
PT (1) PT90491B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191090A (en) * 1990-01-25 1993-03-02 Syntex (U.S.A.) Inc. Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno[3,2-c]pyridine derivatives therefrom
DK0439404T3 (da) * 1990-01-25 1996-02-12 Sanofi Sa Fremstilling af 2-(2-thienyl)-alkylaminer og derivater deraf samt synthese af 4,5,6,7-thieno- (3,2-c)pyridinderivater ud fra disse
FR2664596B1 (fr) * 1990-07-10 1994-06-10 Sanofi Sa Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese.
AU1947992A (en) * 1991-07-08 1993-01-14 Syntex (U.S.A.) Inc. Preparation of 2-(2-thienyl)ethylamine and synthesis of thieno(3,2-c) pyridine derivatives therefrom
US6043368A (en) * 1996-09-04 2000-03-28 Poli Industria Chimica, S.P.A. Method of making thieno-pyridine derivatives
CN101585842B (zh) * 2009-07-13 2011-07-20 北京赛科药业有限责任公司 氯吡格雷中杂质b的研究及控制方法
CN102432626B (zh) * 2011-11-14 2014-07-02 连云港宏业化工有限公司 4,5,6,7-四氢噻吩[3,2-c]吡啶盐酸盐的合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2215948B1 (da) * 1973-02-01 1976-05-14 Centre Etd Ind Pharma
US3984479A (en) * 1973-11-08 1976-10-05 Aldrich-Boranes, Inc. Preparation of 9-BBN
US4127580A (en) * 1975-02-07 1978-11-28 Parcor Process for the preparation of thieno-pyridine derivatives
US4128561A (en) * 1975-12-12 1978-12-05 Parcor Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof
FR2376860A1 (fr) * 1977-01-07 1978-08-04 Parcor Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique
IT1082336B (it) * 1977-01-27 1985-05-21 Medea Res Srl Processo per la preparazione della 5.2.clorobenzil.4 5 6 7.tetraidro tien 3 2.c.piridina
FR2397417A1 (fr) * 1977-07-12 1979-02-09 Parcor Procede de preparation de derives de la thienopyridine
FR2508456A1 (fr) * 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de (thienyl-2)-2 ethylamines et (thienyl-3)-2 ethylamines
JPS6185391A (ja) * 1984-10-03 1986-04-30 Nisshin Flour Milling Co Ltd 5−(2−クロロベンジル)−4,5,6,7−テトラヒドロチエノ〔3,2−c〕ピリジンの製造方法
JPS61271291A (ja) * 1985-05-27 1986-12-01 Asahi Chem Ind Co Ltd チエノピリジン誘導体の製造方法
JPS62103087A (ja) * 1985-10-28 1987-05-13 Toyo Pharma- Kk 5−(2−クロロベンジル)−4,5,6,7−テトラヒドロチエノ〔3,2−c〕ピリジン又はその塩の製造方法
JPS62103088A (ja) * 1985-10-28 1987-05-13 Toyo Pharma- Kk 4,5,6,7−テトラヒドロチエノ〔3,2−c〕ピリジン又はその塩の製造方法
FR2608607B1 (fr) * 1986-12-23 1989-04-28 Sanofi Sa Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
DK227689D0 (da) 1989-05-09
AU626861B2 (en) 1992-08-13
KR890017260A (ko) 1989-12-15
AU3454689A (en) 1989-11-16
US4906756A (en) 1990-03-06
PT90491B (pt) 1995-12-29
JPH01319485A (ja) 1989-12-25
EP0342118A1 (en) 1989-11-15
KR970009227B1 (ko) 1997-06-09
PT90491A (pt) 1989-11-30
NZ229046A (en) 1991-10-25

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