DK2230991T3 - System til glykæmisk kontrol - Google Patents

System til glykæmisk kontrol Download PDF

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Publication number
DK2230991T3
DK2230991T3 DK08865380.3T DK08865380T DK2230991T3 DK 2230991 T3 DK2230991 T3 DK 2230991T3 DK 08865380 T DK08865380 T DK 08865380T DK 2230991 T3 DK2230991 T3 DK 2230991T3
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DK
Denmark
Prior art keywords
glucose
hbalc
patient
pump
insulin
Prior art date
Application number
DK08865380.3T
Other languages
English (en)
Inventor
Gali Shapira
Ofer Yodfat
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
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Publication of DK2230991T3 publication Critical patent/DK2230991T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Emergency Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Claims (8)

1. Bærbar insulinafgivelses system (1000), der omfatter: en bærbar insulinafgivelsespumpe (1005) til at afgive insulin til en patient; en glucosemåler (1006) til periodisk at udføre en flerhed af glucosemålinger svarende til glucosekoncentration i blodet; en processor (10) til at bestemme én eller flere HbAlc-værdier, der er repræsentative for en patients glycosylerede hæmoglobinniveauer baseret på de periodiske glucosemålinger; kendetegnet ved, at: processoren (10) er tilvejebragt i et hvilket som helst eller flere af det bærbare insulinafgivelses system (1000), en håndholdt fjernstyringsenhed (1008) til insulinafgivelsespumpen og en håndholdt blodgluc o semonitor (90); processoren (10) er konfigureret til at bestemme én eller flere HbAlc-værdier baseret på en matematisk model, der sætter den ene eller flere HbAlc-værdier i forhold til glucosekoncentrationer bestemt ud fra glucosemålingerne, idet den matematiske model omfatter en reaktionskinetikmodel af første orden, der er repræsentativ for en reaktionskinetik af første orden mellem glucose og hæmoglobin og tab af HbAlc via erytrocyt-clearance, hvor HbAlc vurderes at være et stabilt reaktionsprodukt; og systemet er konfigureret til advare patienten, hvis en høj HbAlc-værdi fastslås, idet det anbefaler helbredskontrol hos en læge.
2. Bærbart insulinafgivelsessystem (1000) ifølge krav 1, hvor glucosemåleren (1006) er koblet til afgivelsespumpen (1005) og konfigureret til periodisk at udføre en flerhed af glucosemålinger i interstitielfluid.
3. System (1000) ifølge krav 1, hvor systemet endvidere er konfigureret til udføre indstillingsændringer af afgivelsespumpen (1005), hvis en høj HbAlc-værdi fastslås.
4. System (1000) ifølge krav 1, hvor processoren (10) endvidere er konfigureret til beregne én eller flere værdier, der er repræsentative for patientens glucosevariabilitetsniveauer.
5. System (1000) ifølge krav 1, hvor mindst en del af pumpen (1005) kan fastgøres til patientens hud.
6. System (1000) ifølge krav 1, hvor pumpen (1005) omfatter glucosemåleren (1006).
7. System (1000) ifølge krav 1, hvor pumpen omfatter en del (2) til engangsbrug og en genanvendelsesdel (1).
8. System (1000) ifølge krav 1, hvor den ene eller flere HbAlc-værdier beregnes baseret på en gennemsnitlig tidsvægtet beregning af glucosemålingeme.
DK08865380.3T 2007-12-26 2008-12-25 System til glykæmisk kontrol DK2230991T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US929607P 2007-12-26 2007-12-26
PCT/IL2008/001668 WO2009081404A1 (en) 2007-12-26 2008-12-25 System and method for glycemic control

Publications (1)

Publication Number Publication Date
DK2230991T3 true DK2230991T3 (da) 2018-08-06

Family

ID=40512280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08865380.3T DK2230991T3 (da) 2007-12-26 2008-12-25 System til glykæmisk kontrol

Country Status (5)

Country Link
US (1) US20100280499A1 (da)
EP (1) EP2230991B1 (da)
DK (1) DK2230991T3 (da)
ES (1) ES2680896T3 (da)
WO (1) WO2009081404A1 (da)

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Also Published As

Publication number Publication date
US20100280499A1 (en) 2010-11-04
EP2230991A1 (en) 2010-09-29
ES2680896T3 (es) 2018-09-11
WO2009081404A1 (en) 2009-07-02
EP2230991B1 (en) 2018-07-04

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