DK2171034T3 - Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces - Google Patents

Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces

Info

Publication number
DK2171034T3
DK2171034T3 DK08774069.2T DK08774069T DK2171034T3 DK 2171034 T3 DK2171034 T3 DK 2171034T3 DK 08774069 T DK08774069 T DK 08774069T DK 2171034 T3 DK2171034 T3 DK 2171034T3
Authority
DK
Denmark
Prior art keywords
biopolymer
preparing
fermentation process
continuous perfusion
perfusion fermentation
Prior art date
Application number
DK08774069.2T
Other languages
English (en)
Inventor
Mads Laustsen
Original Assignee
Cmc Biolog As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38229532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2171034(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cmc Biolog As filed Critical Cmc Biolog As
Application granted granted Critical
Publication of DK2171034T3 publication Critical patent/DK2171034T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK08774069.2T 2007-06-13 2008-06-11 Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces DK2171034T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07110227A EP2014760A1 (en) 2007-06-13 2007-06-13 A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
PCT/EP2008/057332 WO2008152075A1 (en) 2007-06-13 2008-06-11 A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process

Publications (1)

Publication Number Publication Date
DK2171034T3 true DK2171034T3 (da) 2012-02-13

Family

ID=38229532

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08774069.2T DK2171034T3 (da) 2007-06-13 2008-06-11 Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces

Country Status (6)

Country Link
US (1) US8679778B2 (da)
EP (2) EP2014760A1 (da)
AT (1) ATE530632T1 (da)
DK (1) DK2171034T3 (da)
ES (1) ES2375780T3 (da)
WO (1) WO2008152075A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2579957T3 (es) 2006-07-14 2016-08-17 Dpx Holdings B.V. Procedimiento mejorado para el cultivo de células
ES2556454T3 (es) 2010-10-05 2016-01-18 Novo Nordisk Health Care Ag Proceso para producción de proteínas
EA026017B1 (ru) * 2010-12-23 2017-02-28 Геннова Байофармасьютикалз Лтд. Фармацевтические композиции тенектеплазы
SI2699587T1 (sl) 2011-04-22 2019-08-30 Wyeth Llc Sestavek, povezan z mutantskim clostridium difficile toksinom, in metode omenjenega sestavka
US10493151B2 (en) 2011-10-18 2019-12-03 Coherus Biosciences, Inc. Etanercept formulations stabilized with sodium chloride
JP6220789B2 (ja) 2011-10-18 2017-10-25 コヒラス・バイオサイエンシズ・インコーポレイテッド 糖およびポリオールの組合せによって安定化されたエタネルセプト製剤
WO2013066149A1 (en) * 2011-11-02 2013-05-10 Universiti Putra Malaysia A method for producing a biopolymer
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
CA2878508A1 (en) 2012-07-09 2014-01-16 Coherus Biosciences, Inc. Etanercept formulations exhibiting marked reduction in sub-visible particles
CN104902914B (zh) 2012-09-11 2019-01-01 科荣生生物科学公司 高纯度和优异产量的正确折叠的依那西普
BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
ES2842350T3 (es) 2013-03-19 2021-07-13 Cmc Biologics As Un procedimiento para la producción de un producto (por ejemplo, polipéptido) en un proceso de fermentación de cultivo celular continuo
EP3391942A1 (en) * 2013-03-26 2018-10-24 Coherus Biosciences, Inc. Protein production method
WO2015117884A1 (en) 2014-02-07 2015-08-13 Cmc Biologics A/S A chromatography system and method for capturing a biopolymer
AU2015248888A1 (en) * 2014-04-16 2016-10-20 Cmc Biologics A/S A high cell density fill and draw fermentation process
SG10202113019XA (en) * 2014-06-04 2021-12-30 Amgen Inc Methods for harvesting mammalian cell cultures
EP3158055B1 (en) * 2014-06-13 2019-09-11 CSL Limited Improved production of recombinant von willebrand factor in a bioreactor
JP6530171B2 (ja) * 2014-09-09 2019-06-12 旭化成メディカル株式会社 培養産生物の回収方法
RU2730656C2 (ru) 2015-05-29 2020-08-24 Гликотоп Гмбх Маломасштабный способ культивирования суспендированных клеток
CN109689191B (zh) * 2016-07-25 2021-11-19 瑞普利金公司 交替切向流快速收获
JP2023546736A (ja) 2020-10-15 2023-11-07 エージーシー バイオロジクス，インコーポレーテッド 二重容器接線流濾過による連続的高細胞密度培養

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286646A (en) 1985-11-25 1994-02-15 Boehringer Mannheim Gmbh Method for mammalian cell culture
US4709442A (en) * 1986-10-21 1987-12-01 Advance Machine Company Portable extractor
DE3641824A1 (de) * 1986-12-06 1988-06-16 Bayer Ag Verfahren und vorrichtung zur kultivierung immobilisierter oder adhaerierter saeugerzellen sowie dessen verwendung bei der herstellung von proteinen
US4806484A (en) 1987-08-07 1989-02-21 Igb Products, Ltd. Perfusion airlift bioreactor
US5342781A (en) 1993-07-15 1994-08-30 Su Wei Wen W External-loop perfusion air-lift bioreactor
US6544424B1 (en) 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
CN1250733C (zh) * 2001-04-20 2006-04-12 纳幕尔杜邦公司 一种用于生物发酵系统的产物收取方法
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
AU2005229359C1 (en) 2004-03-05 2011-07-28 Patheon Holdings I B.V. Process for cell culturing by continuous perfusion and alternating tangential flow

Also Published As

Publication number Publication date
US8679778B2 (en) 2014-03-25
ES2375780T3 (es) 2012-03-06
US20100184149A1 (en) 2010-07-22
WO2008152075A1 (en) 2008-12-18
EP2014760A1 (en) 2009-01-14
ATE530632T1 (de) 2011-11-15
EP2171034A1 (en) 2010-04-07
EP2171034B1 (en) 2011-10-26

Similar Documents

Publication Publication Date Title
DK2171034T3 (da) Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces
BRPI0811177A2 (pt) Titulações de polipeptídeo do fator viii em culturas de células
IL212387A0 (en) Perfusion bioreactors, cell culture systems, and methods for production of cells and cell-derived products
PL1828065T3 (pl) Sposób zwiększonej produkcji biogazu w termofilowych, beztlenowych fermentatorach
MX2007005132A (es) Medios libres de proteina animal para cultivo de celulas.
WO2008154014A3 (en) A method for culturing mammalian cells to improve recombinant protein production
DE602005002829D1 (de) Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen
EP2749652A3 (en) A method for producing a target substance by fermentation
IL210491A0 (en) System and method for controlling a mammalian cell culture process
MY169935A (en) "a method for reducing heterogeneity of antibodies and a process of producing the antibodies thereof"
CL2011001926A1 (es) Biorreactor para el cultivo de celulas de mamiferos donde dicho biorreactor posee un volumen de al menos 4000 l y al menos un impulsor superior y al menos un impulsor de fondo, donde el impulsor superior es un impulsor de hidroplano; metodo de cultivo; sistema de bioreactor.
MX347843B (es) Un microorganismo para la producción de metionina con importación de glucosa mejorada.
IN2012DN05207A (da)
MX2010002426A (es) Agente para promover la adhesion de las celulas del endotelio corneal.
WO2008102572A1 (ja) Ｌ－アミノ酸または核酸の製造方法
BR112013020217A2 (pt) método e biorreator para o cultivo de micro-organismos
WO2013112939A3 (en) Methods for succinate production
EA201000901A1 (ru) Способ культивирования микроорганизмов, относящихся к порядку thraustochytriales
EA200800711A1 (ru) Способ культивирования микроорганизмов
WO2012032109A3 (de) Verfahren und vorrichtung zur herstellung von methan in einem photobioreaktor
MX2011012486A (es) Producto alimenticio fermentado a base de soya.
WO2010038912A3 (ja) 微細藻類の培養方法及び装置
DK2242848T3 (da) Clostridium sartagoformum til fremstilling af biogas
FR2938268B1 (fr) Procede de culture de micro-organismes, bioreacteur de mise en oeuvre et procede de fabrication d'un tel bioreacteur
WO2009121211A8 (zh) 一种发酵控制系统及发酵控制方法