DK2055718T3 - Målsøgning og sporing af antigener i levende celler - Google Patents

Målsøgning og sporing af antigener i levende celler

Info

Publication number
DK2055718T3
DK2055718T3 DK08019358.4T DK08019358T DK2055718T3 DK 2055718 T3 DK2055718 T3 DK 2055718T3 DK 08019358 T DK08019358 T DK 08019358T DK 2055718 T3 DK2055718 T3 DK 2055718T3
Authority
DK
Denmark
Prior art keywords
tracing
targeting
live cells
antigen antigens
antigens
Prior art date
Application number
DK08019358.4T
Other languages
English (en)
Inventor
Ulrich Rothbauer
Heinrich Leonhardt
Original Assignee
Univ Muenchen L Maximilians
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen L Maximilians filed Critical Univ Muenchen L Maximilians
Application granted granted Critical
Publication of DK2055718T3 publication Critical patent/DK2055718T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK08019358.4T 2005-11-11 2006-11-13 Målsøgning og sporing af antigener i levende celler DK2055718T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05024739A EP1785434A1 (en) 2005-11-11 2005-11-11 Targeting and tracing of antigens in living cells
EP20060818501 EP1945673B1 (en) 2005-11-11 2006-11-13 Targeting and tracing of antigens in living cells

Publications (1)

Publication Number Publication Date
DK2055718T3 true DK2055718T3 (da) 2013-04-02

Family

ID=36580398

Family Applications (2)

Application Number Title Priority Date Filing Date
DK08019358.4T DK2055718T3 (da) 2005-11-11 2006-11-13 Målsøgning og sporing af antigener i levende celler
DK06818501.6T DK1945673T3 (da) 2005-11-11 2006-11-13 Målretning og sporing af antigener i levende celler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK06818501.6T DK1945673T3 (da) 2005-11-11 2006-11-13 Målretning og sporing af antigener i levende celler

Country Status (7)

Country Link
US (2) US20090136934A1 (da)
EP (3) EP1785434A1 (da)
CA (1) CA2628388C (da)
DK (2) DK2055718T3 (da)
ES (2) ES2401359T3 (da)
PL (2) PL1945673T3 (da)
WO (1) WO2007068313A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2078750B1 (en) * 2008-01-09 2016-09-28 Ludwig-Maximilians-Universität München A fluorescent two-hybrid (F2H) assay for direct visualization of protein interactions in living cells
EP2275442A1 (en) * 2009-07-06 2011-01-19 Ludwig-Maximilians-Universität München Detection and vizualization of the cell cycle in living cells
CN103842563B (zh) 2011-06-29 2017-03-15 亲和生物科学公司 蛋白质展示方法
EP2685260A1 (en) * 2012-07-09 2014-01-15 Ludwig-Maximilians-Universität München Direct and quantitative detection of targets in living cells
FR3007411B1 (fr) * 2013-06-21 2015-07-03 Agronomique Inst Nat Rech Anticorps monocatenaire a chaine lourde de camelide dirige contre la chromatine et utilisations
WO2015200626A1 (en) * 2014-06-25 2015-12-30 The Rockefeller University Compositions and methods for rapid production of versatile nanobody repertoires
WO2016207313A1 (en) * 2015-06-24 2016-12-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for detecting protein-protein interactions
CN110759996B (zh) * 2018-07-27 2022-09-06 深圳康体生命科技有限公司 一种gfp抗体
CN110759997A (zh) * 2018-07-27 2020-02-07 深圳康体生命科技有限公司 一种gfp抗体的制备方法及其抗体
CN110759999A (zh) * 2018-07-27 2020-02-07 深圳康体生命科技有限公司 一种gfp抗体制备方法及其载体
CN110759998A (zh) * 2018-07-27 2020-02-07 深圳康体生命科技有限公司 一种gfp抗体制备方法及其dna序列
EP4077376A2 (en) * 2019-12-19 2022-10-26 Quidel Corporation Monoclonal antibody fusions

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0232262A4 (en) 1985-08-15 1989-09-19 Stauffer Chemical Co MICROORGANISM PRODUCING TRYPTOPHANE.
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
DE59109032D1 (de) 1990-06-28 1998-09-03 Hoechst Ag Fusionsproteine mit immunglobulinanteilen, ihre Herstellung und Verwendung
US5625048A (en) 1994-11-10 1997-04-29 The Regents Of The University Of California Modified green fluorescent proteins
ES2139329T3 (es) 1995-09-22 2000-02-01 Bioimage A S Nuevas variantes de la proteina fluorescente verde, gfp.
ATE332368T1 (de) 1997-01-21 2006-07-15 Gen Hospital Corp Selektion von proteinen mittels rns-protein fusionen
US6261804B1 (en) 1997-01-21 2001-07-17 The General Hospital Corporation Selection of proteins using RNA-protein fusions
ATE388224T1 (de) * 1998-03-27 2008-03-15 Prolume Ltd Luciferase, gfp fluoreszenzproteine, kodierende nukleinsaüre und ihre verwendung in der diagnose
US6414119B1 (en) 1998-10-16 2002-07-02 Rutgers, The State University Rapidly greening, low oxygen mutant of the aequoria victoria green fluorescent protein
AUPP846399A0 (en) 1999-02-02 1999-02-25 University Of Sydney, The Pigment protein from coral tissue
US6281223B1 (en) 1999-04-13 2001-08-28 Supergen, Inc. Radioenhanced camptothecin derivative cancer treatments
US20030013849A1 (en) 1999-10-29 2003-01-16 Ward William W. Renilla reniformis green fluorescent protein
DE60139556D1 (de) 2000-06-19 2009-09-24 Fisher Bioimage Aps Fluoreszierende proteine
JP4213586B2 (ja) * 2001-09-13 2009-01-21 株式会社抗体研究所 ラクダ抗体ライブラリーの作製方法
US20030203355A1 (en) 2002-04-24 2003-10-30 Los Alamos National Laboratory Fluorobodies: binding ligands with intrinsic fluorescence
FR2846667B1 (fr) * 2002-11-06 2004-12-31 Pasteur Institut Fragments variables d'anticorps de camelides a chaine unique diriges contre le peptide beta-amyloide 1-42 et leurs applications pour le diagnostic et le traitement des maladies neuroagregatives
AU2003286004A1 (en) * 2002-11-08 2004-06-07 Ablynx N.V. Single domain antibodies directed against interferon- gamma and uses therefor
CA2510003A1 (en) * 2003-01-16 2004-08-05 Genentech, Inc. Synthetic antibody phage libraries
WO2006040153A2 (en) * 2004-10-13 2006-04-20 Ablynx N.V. Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease

Also Published As

Publication number Publication date
CA2628388C (en) 2018-06-05
WO2007068313A2 (en) 2007-06-21
EP2055718B1 (en) 2012-12-26
CA2628388A1 (en) 2007-06-21
US20090136934A1 (en) 2009-05-28
PL1945673T3 (pl) 2015-10-30
US20130323747A1 (en) 2013-12-05
EP1945673A2 (en) 2008-07-23
EP1785434A1 (en) 2007-05-16
EP2055718A1 (en) 2009-05-06
ES2401359T3 (es) 2013-04-18
PL2055718T3 (pl) 2013-05-31
WO2007068313A3 (en) 2007-09-13
DK1945673T3 (da) 2015-07-13
EP1945673B1 (en) 2015-05-06
ES2542337T3 (es) 2015-08-04

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