FR3007411B1 - Anticorps monocatenaire a chaine lourde de camelide dirige contre la chromatine et utilisations - Google Patents

Anticorps monocatenaire a chaine lourde de camelide dirige contre la chromatine et utilisations

Info

Publication number
FR3007411B1
FR3007411B1 FR1355941A FR1355941A FR3007411B1 FR 3007411 B1 FR3007411 B1 FR 3007411B1 FR 1355941 A FR1355941 A FR 1355941A FR 1355941 A FR1355941 A FR 1355941A FR 3007411 B1 FR3007411 B1 FR 3007411B1
Authority
FR
France
Prior art keywords
camphide
monocatenary
antibody
heavy chain
chain against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1355941A
Other languages
English (en)
Other versions
FR3007411A1 (fr
Inventor
Gladys Mirey
Denis Jullien
Julien Vignard
Bernard Salles
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Toulouse III Paul Sabatier
Institut National de Recherche pour lAgriculture lAlimentation et lEnvironnement
Original Assignee
Institut National de la Recherche Agronomique INRA
Universite Toulouse III Paul Sabatier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Recherche Agronomique INRA, Universite Toulouse III Paul Sabatier filed Critical Institut National de la Recherche Agronomique INRA
Priority to FR1355941A priority Critical patent/FR3007411B1/fr
Priority to US14/899,695 priority patent/US20160145352A1/en
Priority to EP14737174.4A priority patent/EP3010933B1/fr
Priority to PCT/EP2014/062996 priority patent/WO2014202745A1/fr
Publication of FR3007411A1 publication Critical patent/FR3007411A1/fr
Application granted granted Critical
Publication of FR3007411B1 publication Critical patent/FR3007411B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • G—PHYSICS
    • G07—CHECKING-DEVICES
    • G07C—TIME OR ATTENDANCE REGISTERS; REGISTERING OR INDICATING THE WORKING OF MACHINES; GENERATING RANDOM NUMBERS; VOTING OR LOTTERY APPARATUS; ARRANGEMENTS, SYSTEMS OR APPARATUS FOR CHECKING NOT PROVIDED FOR ELSEWHERE
    • G07C1/00—Registering, indicating or recording the time of events or elapsed time, e.g. time-recorders for work people
    • G07C1/30—Parking meters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR1355941A 2013-06-21 2013-06-21 Anticorps monocatenaire a chaine lourde de camelide dirige contre la chromatine et utilisations Active FR3007411B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR1355941A FR3007411B1 (fr) 2013-06-21 2013-06-21 Anticorps monocatenaire a chaine lourde de camelide dirige contre la chromatine et utilisations
US14/899,695 US20160145352A1 (en) 2013-06-21 2014-06-20 Camelid single heavy-chain antibody directed against chromatin and uses of same
EP14737174.4A EP3010933B1 (fr) 2013-06-21 2014-06-20 Anticorps monocaténaire à chaîne lourde de camélidé dirigé contre la chromatine et utilisations
PCT/EP2014/062996 WO2014202745A1 (fr) 2013-06-21 2014-06-20 Anticorps monocaténaire à chaîne lourde de camélidé dirigé contre la chromatine et utilisations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1355941A FR3007411B1 (fr) 2013-06-21 2013-06-21 Anticorps monocatenaire a chaine lourde de camelide dirige contre la chromatine et utilisations

Publications (2)

Publication Number Publication Date
FR3007411A1 FR3007411A1 (fr) 2014-12-26
FR3007411B1 true FR3007411B1 (fr) 2015-07-03

Family

ID=38570971

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1355941A Active FR3007411B1 (fr) 2013-06-21 2013-06-21 Anticorps monocatenaire a chaine lourde de camelide dirige contre la chromatine et utilisations

Country Status (4)

Country Link
US (1) US20160145352A1 (fr)
EP (1) EP3010933B1 (fr)
FR (1) FR3007411B1 (fr)
WO (1) WO2014202745A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10441644B2 (en) 2015-05-05 2019-10-15 The Regents Of The University Of California H3.3 CTL peptides and uses thereof
CN110759996B (zh) * 2018-07-27 2022-09-06 深圳康体生命科技有限公司 一种gfp抗体
EP4337691A1 (fr) * 2021-05-12 2024-03-20 Université de Strasbourg Anticorps à domaine unique spécifique de h2ax phosphorylé et ses utilisations

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4493585A (en) * 1984-06-06 1985-12-31 Scripps Clinic And Research Foundation A diagnostic assay for the presence of antibodies associated with drug-induced lupus erythematosus
JP2002510033A (ja) * 1998-01-12 2002-04-02 ザ・サルク・インスティチュート 二重微小ｄｎａを有する細胞を処理するための組成物およびその処理方法
WO2002048193A2 (fr) * 2000-12-13 2002-06-20 Unilever N.V. Réseaux de protéines
US7371849B2 (en) * 2001-09-13 2008-05-13 Institute For Antibodies Co., Ltd. Methods of constructing camel antibody libraries
EP1844073A1 (fr) * 2005-01-31 2007-10-17 Ablynx N.V. Procede de generation de sequences a domaine variable d'anticorps a chaine lourde
US20080253632A1 (en) * 2005-03-30 2008-10-16 Halazonetis Thanos D Method of Detecting Precancerous Lesions
EP1785434A1 (fr) * 2005-11-11 2007-05-16 Ludwig-Maximilians-Universität München Ciblage et suivi d'antigènes dans des cellules vivantes
US8163481B2 (en) * 2007-04-02 2012-04-24 University of Pittsburgh - of the Commonwealth Systems of Higher Education Method of extracting chromatin fractions from intact cells
US20110009387A1 (en) * 2007-06-12 2011-01-13 Andrea Dawn Basso-Porcaro Histone h2ax (hh2ax) biomarker for fti sensitivity
AR062123A1 (es) * 2007-07-27 2008-10-15 Inst Nac De Tecnologia Agropec Dominio vhh monomerico derivado de anticuerpos de camelidos anti-vp6 dominio dimerico, metodo de inmunodeteccion de rotavirus, composiciones, metodos de prevencion y tratamiento de infecciones con rotavirus
AU2008323947B2 (en) * 2007-11-06 2014-02-20 Oklahoma Medical Research Foundation Extracellular histones as biomarkers for prognosis and molecular targets for therapy
CA2726511C (fr) * 2008-06-04 2018-07-10 Modiquest B.V. Agents anti-inflammatoires
US20100080799A1 (en) * 2008-09-17 2010-04-01 The Rockefeller University Wstf regulates the dna damage response of h2a.x via novel tyrosine kinase activity
US8575112B2 (en) * 2009-09-18 2013-11-05 University Of Houston System Small peptide modulators of potassium channel trafficking
EP2332987A1 (fr) * 2009-12-10 2011-06-15 ModiQuest B.V. Agents anti-inflammatoires dirigés vers les épitopes citrullinés
EP2561367A1 (fr) * 2010-04-22 2013-02-27 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Moyens et procédés pour identifier un risque augmenté pour des patients atteints de lupus érythémateux disséminé (led) de développer des manifestations rénales
UA117218C2 (uk) * 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
GB201115099D0 (en) * 2011-09-01 2011-10-19 Belgian Volition Sa Method for detecting nucleosomes
US20140017673A1 (en) * 2012-07-11 2014-01-16 Litron Laboratories, Ltd. Method for enumerating eukaryotic cell micronuclei with an emphasis on simultaneously acquiring cytotoxicity and mode of action information

Also Published As

Publication number Publication date
US20160145352A1 (en) 2016-05-26
WO2014202745A1 (fr) 2014-12-24
EP3010933A1 (fr) 2016-04-27
FR3007411A1 (fr) 2014-12-26
EP3010933B1 (fr) 2024-05-15

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