DK2054363T3 - Asymmetrisk hydrogenering af 1,1,1-trifluoracetone - Google Patents

Asymmetrisk hydrogenering af 1,1,1-trifluoracetone

Info

Publication number
DK2054363T3
DK2054363T3 DK07787638.1T DK07787638T DK2054363T3 DK 2054363 T3 DK2054363 T3 DK 2054363T3 DK 07787638 T DK07787638 T DK 07787638T DK 2054363 T3 DK2054363 T3 DK 2054363T3
Authority
DK
Denmark
Prior art keywords
trifluoracetone
asymmetric hydrogenation
hydrogenation
asymmetric
Prior art date
Application number
DK07787638.1T
Other languages
English (en)
Inventor
Kurt Puentener
Pius Waldmeier
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK2054363T3 publication Critical patent/DK2054363T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/34Halogenated alcohols
    • C07C31/38Halogenated alcohols containing only fluorine as halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK07787638.1T 2006-07-27 2007-07-17 Asymmetrisk hydrogenering af 1,1,1-trifluoracetone DK2054363T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06117928 2006-07-27
PCT/EP2007/057372 WO2008012240A1 (en) 2006-07-27 2007-07-17 Asymmetric hydrogenation of 1,1,1-trifluoroacetone

Publications (1)

Publication Number Publication Date
DK2054363T3 true DK2054363T3 (da) 2013-06-03

Family

ID=38578449

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07787638.1T DK2054363T3 (da) 2006-07-27 2007-07-17 Asymmetrisk hydrogenering af 1,1,1-trifluoracetone

Country Status (15)

Country Link
US (1) US7504544B2 (da)
EP (1) EP2054363B1 (da)
JP (1) JP5345932B2 (da)
KR (1) KR101087941B1 (da)
CN (1) CN101500974B (da)
AU (1) AU2007278274B2 (da)
BR (1) BRPI0715096B1 (da)
CA (1) CA2658773C (da)
DK (1) DK2054363T3 (da)
ES (1) ES2411713T3 (da)
IL (1) IL196327A (da)
MX (1) MX2009000616A (da)
PL (1) PL2054363T3 (da)
SI (1) SI2054363T1 (da)
WO (1) WO2008012240A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101796050B (zh) 2007-09-06 2015-08-12 日本曹达株式会社 光学活性3-奎核醇衍生物的制造方法
CN101983186B (zh) * 2008-04-07 2013-12-11 日本曹达株式会社 钌化合物和光学活性氨基醇化合物的制造方法
ES2863542T3 (es) 2009-03-17 2021-10-11 Johnson Matthey Plc Proceso para la hidrogenación de cetonas en presencia de catalizadores de Ru (II)
JP5656474B2 (ja) 2010-06-28 2015-01-21 関東化学株式会社 脂肪族光学活性フルオロアルコールの製造方法
CN104447205A (zh) * 2014-11-27 2015-03-25 广东东阳光药业有限公司 制备(s)-三氟异丙醇的方法
CN107815468B (zh) 2016-08-31 2021-03-16 百奥赛图(北京)医药科技股份有限公司 人源化基因改造动物模型的制备方法及应用
WO2021142329A1 (en) 2020-01-09 2021-07-15 Disc Medicine, Inc. Methods of treating erythropoietic protoporphyria, x-linked protoporphyria, or congenital erythropoietic porphyria with glycine transport inhibitors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0398132T3 (da) 1989-05-18 1995-12-18 Hoffmann La Roche Phosphorforbindelser
DK0530335T3 (da) 1991-03-15 1996-10-14 Hoffmann La Roche Disphosphonsyrederivater som mellemprodukter til fremstillingen af diphosphinligander
US5256321A (en) 1992-07-10 1993-10-26 The Lubrizol Corporation Grease compositions
JP4674393B2 (ja) * 2000-06-21 2011-04-20 ダイキン工業株式会社 光学活性な含フッ素β−ヒドロキシエステルの製造方法
JP4286486B2 (ja) * 2001-01-15 2009-07-01 日本曹達株式会社 ルテニウム化合物、ジアミン配位子および光学活性アルコールの製造方法
FR2830254B1 (fr) * 2001-09-28 2004-09-17 Synkem Nouvelles diphosphines, leurs complexes avec des metaux de transition et leur utilisation en synthese asymetrique
JP4919562B2 (ja) * 2001-09-28 2012-04-18 日本曹達株式会社 ルテニウムヒドリド錯体、アルコール化合物の製造方法およびラセミ体カルボニル化合物の分割方法
CN1166672C (zh) * 2001-12-07 2004-09-15 中国科学院上海有机化学研究所 非c2对称轴手性双膦配体的金属络合物、合成方法及其在酮的不对称催化氢化中的应用
JP3566955B2 (ja) * 2001-12-28 2004-09-15 関東化学株式会社 新規ルテニウム錯体およびこれを触媒として用いるアルコール化合物の製造方法
WO2003061826A1 (en) * 2002-01-24 2003-07-31 Dsm Ip Assets B.V. Process for preparing nonracemic chiral alcohols
FR2849036B1 (fr) * 2002-12-18 2005-05-20 Rhodia Chimie Sa Diphosphines chirales, leur preparation et leurs utilisations comme ligands dans la synthese de complexes destines a la catalyse asymetrique
DK1656361T3 (da) 2003-08-11 2008-05-05 Hoffmann La Roche Piperazin med OR-substitueret phenylgruppe og anvendelse deraf som GLYT1-inhibitorer
EP1661903B8 (en) * 2003-08-13 2011-10-19 Takasago International Corporation Novel transition metal complex and process for producing optically active alcohol with the complex
KR100946461B1 (ko) * 2005-07-08 2010-03-10 에프. 호프만-라 로슈 아게 1,1,1-트라이플루오로아세톤의 비대칭 환원

Also Published As

Publication number Publication date
KR101087941B1 (ko) 2011-11-28
US20080027249A1 (en) 2008-01-31
SI2054363T1 (sl) 2013-06-28
MX2009000616A (es) 2009-01-28
ES2411713T3 (es) 2013-07-08
KR20090023505A (ko) 2009-03-04
AU2007278274A1 (en) 2008-01-31
WO2008012240A1 (en) 2008-01-31
CN101500974B (zh) 2013-03-20
EP2054363B1 (en) 2013-04-17
CN101500974A (zh) 2009-08-05
JP2009544653A (ja) 2009-12-17
IL196327A (en) 2011-12-29
JP5345932B2 (ja) 2013-11-20
US7504544B2 (en) 2009-03-17
EP2054363A1 (en) 2009-05-06
CA2658773C (en) 2014-04-08
PL2054363T3 (pl) 2013-09-30
AU2007278274B2 (en) 2012-09-13
CA2658773A1 (en) 2008-01-31
IL196327A0 (en) 2009-09-22
BRPI0715096A2 (pt) 2013-03-26
BRPI0715096B1 (pt) 2016-11-08

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