DK2032230T3 - Fremgangsmåde til optimering af kromatografiske oprensningsfremgangsmåder til biomolekyler - Google Patents
Fremgangsmåde til optimering af kromatografiske oprensningsfremgangsmåder til biomolekylerInfo
- Publication number
- DK2032230T3 DK2032230T3 DK07765375.6T DK07765375T DK2032230T3 DK 2032230 T3 DK2032230 T3 DK 2032230T3 DK 07765375 T DK07765375 T DK 07765375T DK 2032230 T3 DK2032230 T3 DK 2032230T3
- Authority
- DK
- Denmark
- Prior art keywords
- biomolecules
- purification methods
- chromatographic purification
- optimizing chromatographic
- optimizing
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/52—Physical parameters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
- G01N30/56—Packing methods or coating methods
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
- B01D15/203—Equilibration or regeneration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N2030/009—Extraction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/466—Flow patterns using more than one column with separation columns in parallel
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8658—Optimising operation parameters
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006027496A DE102006027496B3 (de) | 2006-06-14 | 2006-06-14 | Verfahren zur Optimierung chromatographischer Reinigungsverfahren für Biomoleküle |
| PCT/EP2007/055776 WO2007144353A1 (de) | 2006-06-14 | 2007-06-12 | Verfahren zur optimierung chromatographischer reinigungsverfahren für biomoleküle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2032230T3 true DK2032230T3 (da) | 2014-05-12 |
Family
ID=38529642
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07765375.6T DK2032230T3 (da) | 2006-06-14 | 2007-06-12 | Fremgangsmåde til optimering af kromatografiske oprensningsfremgangsmåder til biomolekyler |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8349615B2 (da) |
| EP (1) | EP2032230B1 (da) |
| JP (1) | JP5168276B2 (da) |
| KR (1) | KR101365474B1 (da) |
| CA (1) | CA2655258C (da) |
| DE (1) | DE102006027496B3 (da) |
| DK (1) | DK2032230T3 (da) |
| ES (1) | ES2462392T3 (da) |
| TW (1) | TWI435753B (da) |
| WO (1) | WO2007144353A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2337632B1 (en) | 2008-10-15 | 2018-04-11 | GE Healthcare BioProcess R&D AB | Micro titre plate |
| CA2821711C (en) | 2010-12-15 | 2017-10-10 | Baxter International Inc. | Eluate collection using conductivity gradient |
| WO2019165148A1 (en) * | 2018-02-21 | 2019-08-29 | Just Biotherapeutics, Inc. | Determining conditions for purification of proteins |
| CN112843789A (zh) * | 2020-12-29 | 2021-05-28 | 上海赛梵科分离技术有限公司 | 大麻二酚纯化中色谱填料和层析介质的再生方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19860354B4 (de) * | 1998-12-24 | 2006-11-23 | Universität Dortmund | Eine Methode zur modellbasierten on-line Optimierung und Parameterschätzung von Batch-Chromatographieprozessen |
| US20050176937A1 (en) * | 2000-02-23 | 2005-08-11 | Rensselaer Polytechnic Institute | High throughput screening of potential displacer molecules |
| US20060096924A1 (en) * | 2002-09-19 | 2006-05-11 | Hartmut Schlueter | Method for discovering suitable chromatography conditions for the separation of biological molecules |
-
2006
- 2006-06-14 DE DE102006027496A patent/DE102006027496B3/de active Active
-
2007
- 2007-06-12 KR KR1020097000808A patent/KR101365474B1/ko not_active IP Right Cessation
- 2007-06-12 WO PCT/EP2007/055776 patent/WO2007144353A1/de active Application Filing
- 2007-06-12 CA CA2655258A patent/CA2655258C/en not_active Expired - Fee Related
- 2007-06-12 JP JP2009514784A patent/JP5168276B2/ja not_active Expired - Fee Related
- 2007-06-12 ES ES07765375.6T patent/ES2462392T3/es active Active
- 2007-06-12 EP EP07765375.6A patent/EP2032230B1/de active Active
- 2007-06-12 DK DK07765375.6T patent/DK2032230T3/da active
- 2007-06-13 US US11/762,119 patent/US8349615B2/en active Active
- 2007-06-13 TW TW096121335A patent/TWI435753B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20080066530A1 (en) | 2008-03-20 |
| KR20090032082A (ko) | 2009-03-31 |
| JP2009539931A (ja) | 2009-11-19 |
| CA2655258A1 (en) | 2007-12-21 |
| TWI435753B (zh) | 2014-05-01 |
| TW200815079A (en) | 2008-04-01 |
| JP5168276B2 (ja) | 2013-03-21 |
| US8349615B2 (en) | 2013-01-08 |
| ES2462392T3 (es) | 2014-05-22 |
| DE102006027496B3 (de) | 2008-01-10 |
| WO2007144353A1 (de) | 2007-12-21 |
| EP2032230B1 (de) | 2014-04-02 |
| EP2032230A1 (de) | 2009-03-11 |
| CA2655258C (en) | 2014-04-29 |
| KR101365474B1 (ko) | 2014-02-21 |
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