DK1996626T3 - Anti-idiotype antistoffer, der neutraliserer den inhibitoriske aktivitet af et inhibitorisk antistof, der er rettet mod C1-domænet af faktor VIII - Google Patents

Anti-idiotype antistoffer, der neutraliserer den inhibitoriske aktivitet af et inhibitorisk antistof, der er rettet mod C1-domænet af faktor VIII

Info

Publication number
DK1996626T3
DK1996626T3 DK07731046.4T DK07731046T DK1996626T3 DK 1996626 T3 DK1996626 T3 DK 1996626T3 DK 07731046 T DK07731046 T DK 07731046T DK 1996626 T3 DK1996626 T3 DK 1996626T3
Authority
DK
Denmark
Prior art keywords
tyr
ser
thr
asn
ala
Prior art date
Application number
DK07731046.4T
Other languages
English (en)
Inventor
Jean-Guy Gilles
Marc G Jacquemin
Jean-Marie Saint-Remy
Christian Behrens
Original Assignee
Lfb Biotechnologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lfb Biotechnologies filed Critical Lfb Biotechnologies
Application granted granted Critical
Publication of DK1996626T3 publication Critical patent/DK1996626T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
DK07731046.4T 2006-02-24 2007-02-26 Anti-idiotype antistoffer, der neutraliserer den inhibitoriske aktivitet af et inhibitorisk antistof, der er rettet mod C1-domænet af faktor VIII DK1996626T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0601633A FR2897868B1 (fr) 2006-02-24 2006-02-24 Anticorps anti-idiotypiques neutralisant l'activite inhibitrice d'un anticorps inhibiteur dirige contre le domaine c1 du facteur viii.
PCT/FR2007/000342 WO2007096536A1 (fr) 2006-02-24 2007-02-26 Anticorps anti-idiotypiques neutralisant l'activite inhibitrice d'un anticorps inhibiteur dirige contre le domaine c1 du facteur viii

Publications (1)

Publication Number Publication Date
DK1996626T3 true DK1996626T3 (da) 2012-02-13

Family

ID=37106244

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07731046.4T DK1996626T3 (da) 2006-02-24 2007-02-26 Anti-idiotype antistoffer, der neutraliserer den inhibitoriske aktivitet af et inhibitorisk antistof, der er rettet mod C1-domænet af faktor VIII

Country Status (15)

Country Link
US (2) US20080160015A1 (da)
EP (3) EP2447284A1 (da)
JP (1) JP2009528285A (da)
KR (1) KR20080106289A (da)
CN (1) CN101522718A (da)
AT (1) ATE530579T1 (da)
AU (1) AU2007217218A1 (da)
BR (1) BRPI0707031A2 (da)
CA (1) CA2643565A1 (da)
DK (1) DK1996626T3 (da)
ES (1) ES2376489T3 (da)
FR (1) FR2897868B1 (da)
IL (1) IL193212A0 (da)
PL (1) PL1996626T3 (da)
WO (1) WO2007096536A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2889534B1 (fr) * 2005-08-04 2012-11-02 Lab Francais Du Fractionnement Anticorps anti-idiotypique neutralisant l'activite inhibitrice d'un anticorps inhibiteur du facteur viii
JP2010536363A (ja) * 2007-08-23 2010-12-02 エルエフビー バイオテクノロジース ファクターｖｉｉｉのｃ１ドメインに対する阻害抗体の阻害活性を中性化する抗イデオタイプ抗体
FR2933496B1 (fr) * 2008-07-02 2012-10-05 Lfb Biotechnologies Procede de mesure du taux de facteur vii active dans un echantillon
US8716448B2 (en) 2009-02-03 2014-05-06 Amunix Operating Inc. Coagulation factor VII compositions and methods of making and using same
FR2969761A1 (fr) * 2010-12-22 2012-06-29 Lfb Biotechnologies Procede de dosage d'anticorps diriges contre le facteur viii
KR20190094480A (ko) 2012-02-15 2019-08-13 바이오버라티브 테라퓨틱스 인크. 재조합 인자 viii 단백질
CN111548418A (zh) 2012-02-15 2020-08-18 比奥贝拉蒂治疗公司 因子viii组合物及其制备和使用方法
WO2014066744A2 (en) 2012-10-25 2014-05-01 True North Therapeutics, Inc. Anti-complement c1s antibodies and uses thereof
RS63212B1 (sr) 2012-11-02 2022-06-30 Bioverativ Usa Inc Antikomplementna c1s antitela i njihove primene
TW202003554A (zh) 2013-08-14 2020-01-16 美商百歐維拉提夫治療公司 因子ｖｉｉｉ－ｘｔｅｎ融合物及其用途
PT3280440T (pt) 2015-04-06 2023-02-14 Bioverativ Usa Inc Anticorpos anti-c1s humanizados e métodos de utilização destes
JP6909203B2 (ja) 2015-08-03 2021-07-28 バイオベラティブ セラピューティクス インコーポレイテッド 第ｉｘ因子融合タンパク質及びそれらの製造方法及び使用方法
PE20191031A1 (es) * 2016-10-12 2019-08-05 Bioverativ Usa Inc ANTICUERPOS ANTI-C1s Y METODOS DE USO DE LOS MISMOS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR508320A (fr) 1920-01-12 1920-10-07 Deynoux Freres Fermoir pour sacs et objets analogues
WO2005016455A2 (en) * 2003-08-14 2005-02-24 D. Collen Research Foundation Vzw Antibodies against factor viii with modified glycosylation in the variable region
EP1194528B1 (en) * 1999-07-14 2007-03-07 D. Collen Research Foundation vzw Monoclonal antibody for factor VIII, which even when present in molar excess inactivates factor VIII only in part and a method for producing such an antibody
EP1388544A1 (en) * 2002-07-31 2004-02-11 D. Collen Research Foundation vzw Anti-idiotypic antibodies against factor VIII inhibitor and uses thereof
FR2889534B1 (fr) 2005-08-04 2012-11-02 Lab Francais Du Fractionnement Anticorps anti-idiotypique neutralisant l'activite inhibitrice d'un anticorps inhibiteur du facteur viii

Also Published As

Publication number Publication date
PL1996626T3 (pl) 2012-04-30
EP2447284A1 (fr) 2012-05-02
AU2007217218A1 (en) 2007-08-30
ATE530579T1 (de) 2011-11-15
WO2007096536A1 (fr) 2007-08-30
EP2100903A3 (fr) 2010-01-20
KR20080106289A (ko) 2008-12-04
CN101522718A (zh) 2009-09-02
US20090263380A1 (en) 2009-10-22
EP1996626A1 (fr) 2008-12-03
US20080160015A1 (en) 2008-07-03
FR2897868B1 (fr) 2012-08-31
CA2643565A1 (en) 2007-08-30
ES2376489T3 (es) 2012-03-14
JP2009528285A (ja) 2009-08-06
US8110190B2 (en) 2012-02-07
IL193212A0 (en) 2009-02-11
EP2100903A2 (fr) 2009-09-16
FR2897868A1 (fr) 2007-08-31
EP1996626B1 (fr) 2011-10-26
BRPI0707031A2 (pt) 2011-04-12

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