DK1990410T3 - Immunterapi ved anvendelse af celle, der kan samudtrykke målantigen og CD1d og er pulseret med CD1d-ligand - Google Patents

Immunterapi ved anvendelse af celle, der kan samudtrykke målantigen og CD1d og er pulseret med CD1d-ligand Download PDF

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Publication number
DK1990410T3
DK1990410T3 DK07714709.8T DK07714709T DK1990410T3 DK 1990410 T3 DK1990410 T3 DK 1990410T3 DK 07714709 T DK07714709 T DK 07714709T DK 1990410 T3 DK1990410 T3 DK 1990410T3
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Denmark
Prior art keywords
cd1d
immunotherapy
pulsed
target antigen
cell capable
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DK07714709.8T
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English (en)
Inventor
Shin-Ichiro Fujii
Kanako Shimizu
Original Assignee
Riken
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Publication of DK1990410T3 publication Critical patent/DK1990410T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4643—Vertebrate antigens
    • A61K39/4644—Cancer antigens
    • A61K39/464402—Receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/57—Skin; melanoma
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK07714709.8T 2006-02-22 2007-02-21 Immunterapi ved anvendelse af celle, der kan samudtrykke målantigen og CD1d og er pulseret med CD1d-ligand DK1990410T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006045193 2006-02-22
PCT/JP2007/053209 WO2007097370A1 (ja) 2006-02-22 2007-02-21 ＣＤ１ｄリガンドをパルスした、標的抗原及びＣＤ１ｄの共発現細胞による免疫療法

Publications (1)

Publication Number Publication Date
DK1990410T3 true DK1990410T3 (da) 2020-04-06

Family

ID=38437409

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07714709.8T DK1990410T3 (da) 2006-02-22 2007-02-21 Immunterapi ved anvendelse af celle, der kan samudtrykke målantigen og CD1d og er pulseret med CD1d-ligand

Country Status (12)

Country Link
US (1) US20100233215A1 (da)
EP (2) EP1990410B1 (da)
JP (2) JP5672647B2 (da)
CY (1) CY1122911T1 (da)
DK (1) DK1990410T3 (da)
ES (2) ES2780176T3 (da)
HU (1) HUE049283T2 (da)
LT (1) LT1990410T (da)
PL (1) PL1990410T3 (da)
PT (1) PT1990410T (da)
SI (1) SI1990410T1 (da)
WO (1) WO2007097370A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006135032A1 (ja) * 2005-06-17 2006-12-21 Riken Ｎｋｔ細胞の機能解析法
PT1990410T (pt) * 2006-02-22 2020-03-03 Riken Imunoterapia por utilização de uma célula capaz de co-expressar um antigénio alvo e cd1d e pulsada com um ligando de cd1d
WO2009034961A1 (ja) * 2007-09-10 2009-03-19 Riken ヒト樹状細胞の評価方法およびヒト細胞免疫療法剤
KR100995340B1 (ko) * 2007-11-19 2010-11-19 재단법인서울대학교산학협력재단 자연 살해 ｔ 세포의 리간드와 항원을 적재한 단핵구 또는미분화 골수성 세포를 포함하는 백신
JPWO2010061930A1 (ja) * 2008-11-28 2012-04-26 独立行政法人理化学研究所 ＣＤ１ｄ及び標的抗原の共発現アロ細胞を用いた免疫療法
US9783821B2 (en) 2011-07-29 2017-10-10 Riken Cell for use in immunotherapy which contains modified nucleic acid construct encoding wilms tumor gene product or fragment thereof, method for producing said cell, and said nucleic acid construct
US10316332B2 (en) 2011-07-29 2019-06-11 Riken Cell for immunotherapy, including modified nucleic acid construct encoding Wilms tumor gene product
WO2016093350A1 (ja) * 2014-12-11 2016-06-16 国立研究開発法人理化学研究所 改変型免疫細胞、改変型免疫細胞の製造方法、およびこれらの利用
US10501541B2 (en) * 2015-01-27 2019-12-10 Lava Therapeutics B.V. Single domain antibodies targeting CD1d
JP7125760B2 (ja) * 2019-06-14 2022-08-25 国立研究開発法人理化学研究所 免疫系を賦活化する細胞および当該細胞を含む医薬組成物
EP4011389A1 (en) 2019-08-09 2022-06-15 Riken Combined use of artificial adjuvant vector cells and an immunostimulant
TW202134431A (zh) 2019-12-02 2021-09-16 日商安斯泰來製藥股份有限公司 用於癌症處置之含有ny-eso-1之人工佐劑載體細胞
AU2020398783A1 (en) * 2019-12-02 2022-06-09 Astellas Pharma Inc. METHOD FOR TREATING CANCER USING ARTIFICIAL ADJUVANT CELL (aAVC)
JP2023078487A (ja) * 2020-04-08 2023-06-07 アステラス製薬株式会社 がんの処置に用いるｐｐ６５含有人工アジュバントベクター細胞
WO2022230971A1 (ja) 2021-04-30 2022-11-03 国立研究開発法人理化学研究所 コロナウイルスに対する免疫応答を誘発する人工アジュバントベクター細胞、および当該細胞を含む医薬組成物、並びにそれらの使用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1016418B1 (en) 1994-10-03 2009-12-30 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Host cell comprising a recombinant virus expressing an antigen and a recombinant virus expressing an immunostimulatory molecule
US20040214783A1 (en) * 2002-05-08 2004-10-28 Terman David S. Compositions and methods for treatment of neoplastic disease
JP2002112780A (ja) 2000-10-03 2002-04-16 Keio Gijuku ヒト膀胱癌抗原
JP2004147649A (ja) 2002-10-11 2004-05-27 Kumamoto Technology & Industry Foundation 頭頚部癌の抗原
HU0301358D0 (en) * 2003-05-14 2003-07-28 Debreceni Egyetem Novel use of ppargamma agonists
JP2005139118A (ja) 2003-11-07 2005-06-02 Ortho Mcneil Pharmaceut Inc 腫瘍の治療のための細胞治療方法
JP5002915B2 (ja) 2004-07-01 2012-08-15 住友化学株式会社 光学活性なシクロプロパンカルボン酸エステル化合物の製造方法およびそれに用いる不斉銅錯体
JPWO2007043630A1 (ja) * 2005-10-06 2009-04-16 独立行政法人理化学研究所 上気道粘膜下に投与されるｎｋｔ細胞刺激剤
PT1990410T (pt) * 2006-02-22 2020-03-03 Riken Imunoterapia por utilização de uma célula capaz de co-expressar um antigénio alvo e cd1d e pulsada com um ligando de cd1d
US10316332B2 (en) * 2011-07-29 2019-06-11 Riken Cell for immunotherapy, including modified nucleic acid construct encoding Wilms tumor gene product
AU2020398783A1 (en) * 2019-12-02 2022-06-09 Astellas Pharma Inc. METHOD FOR TREATING CANCER USING ARTIFICIAL ADJUVANT CELL (aAVC)

Also Published As

Publication number Publication date
EP2441468A2 (en) 2012-04-18
PT1990410T (pt) 2020-03-03
ES2774707T3 (es) 2020-07-22
JP5672647B2 (ja) 2015-02-18
EP1990410A1 (en) 2008-11-12
EP1990410B1 (en) 2020-01-08
EP1990410A4 (en) 2009-08-26
PL1990410T3 (pl) 2020-07-13
US20100233215A1 (en) 2010-09-16
LT1990410T (lt) 2020-03-10
EP2441468A3 (en) 2012-10-17
JPWO2007097370A1 (ja) 2009-07-16
JP5673723B2 (ja) 2015-02-18
CY1122911T1 (el) 2021-10-29
JP2013212107A (ja) 2013-10-17
EP2441468B1 (en) 2020-01-08
SI1990410T1 (sl) 2020-07-31
ES2780176T3 (es) 2020-08-24
HUE049283T2 (hu) 2020-09-28
WO2007097370A1 (ja) 2007-08-30

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