DK1968651T3 - Stabiliserede sammensætninger og fremgangsmåder til radioaktiv mærkning af lægemidler med alfa-partikelemittere - Google Patents

Stabiliserede sammensætninger og fremgangsmåder til radioaktiv mærkning af lægemidler med alfa-partikelemittere

Info

Publication number
DK1968651T3
DK1968651T3 DK06850596.5T DK06850596T DK1968651T3 DK 1968651 T3 DK1968651 T3 DK 1968651T3 DK 06850596 T DK06850596 T DK 06850596T DK 1968651 T3 DK1968651 T3 DK 1968651T3
Authority
DK
Denmark
Prior art keywords
drugs
alpha
methods
radioactive labeling
stabilized compositions
Prior art date
Application number
DK06850596.5T
Other languages
English (en)
Inventor
Michael Rod Zalutsky
Oscar Rodolfo Pozzi
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of DK1968651T3 publication Critical patent/DK1968651T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121Solutions, i.e. homogeneous liquid formulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00Purification; Separation; Stabilisation; Use of additives
    • C07B63/04Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
DK06850596.5T 2005-12-22 2006-12-22 Stabiliserede sammensætninger og fremgangsmåder til radioaktiv mærkning af lægemidler med alfa-partikelemittere DK1968651T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75237005P 2005-12-22 2005-12-22
PCT/US2006/048811 WO2007120251A2 (en) 2005-12-22 2006-12-22 Stabilized compositions and methods for radiolabeling pharmaceuticals with alpha-particle emitters

Publications (1)

Publication Number Publication Date
DK1968651T3 true DK1968651T3 (da) 2013-06-17

Family

ID=38609971

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06850596.5T DK1968651T3 (da) 2005-12-22 2006-12-22 Stabiliserede sammensætninger og fremgangsmåder til radioaktiv mærkning af lægemidler med alfa-partikelemittere

Country Status (6)

Country Link
US (1) US8337810B2 (da)
EP (1) EP1968651B1 (da)
JP (1) JP5264500B2 (da)
CA (1) CA2634666C (da)
DK (1) DK1968651T3 (da)
WO (1) WO2007120251A2 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2843625T3 (es) 2014-06-18 2021-07-19 Alpha Therapy Solutions Ab Plataforma de proceso automático para la producción de radiofármacos marcados con astatina-211 [At-211]
EP3600453A1 (en) * 2017-03-30 2020-02-05 Duke University Radiolabeled biomolecules and their use
EP3663307A4 (en) * 2017-08-04 2021-03-24 Osaka University MANUFACTURING PROCESS FOR RADIOACTIVELY MARKED ARYL COMPOUND
WO2019131998A1 (ja) * 2017-12-29 2019-07-04 国立大学法人大阪大学 アスタチン溶液及びその製造方法
CN111463110B (zh) * 2020-04-15 2023-05-09 武汉华星光电半导体显示技术有限公司 基于溶液法的ito薄膜的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826672A (en) * 1985-06-07 1989-05-02 President And Fellows Of Harvard College Astatinated organic compounds
US5262175A (en) * 1989-05-10 1993-11-16 Solanki Kishor K Stabilization of radiopharmaceutical compositions
US5219556A (en) 1990-07-09 1993-06-15 Mallinckrodt Medical, Inc. Stabilized therapeutic radiopharmaceutical complexes
EP1311301A2 (en) * 2000-07-06 2003-05-21 Bristol-Myers Squibb Pharma Company Stable radiopharmaceutical compositions and methods for preparation thereof

Also Published As

Publication number Publication date
JP5264500B2 (ja) 2013-08-14
US8337810B2 (en) 2012-12-25
JP2009521469A (ja) 2009-06-04
CA2634666C (en) 2015-05-26
EP1968651A2 (en) 2008-09-17
WO2007120251A3 (en) 2007-12-27
CA2634666A1 (en) 2007-10-25
WO2007120251A2 (en) 2007-10-25
EP1968651A4 (en) 2009-10-21
EP1968651B1 (en) 2013-03-13
US20090304585A1 (en) 2009-12-10

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