DK1947172T3 - Konstruktion af metabolisk styring - Google Patents

Konstruktion af metabolisk styring

Info

Publication number
DK1947172T3
DK1947172T3 DK08000125.8T DK08000125T DK1947172T3 DK 1947172 T3 DK1947172 T3 DK 1947172T3 DK 08000125 T DK08000125 T DK 08000125T DK 1947172 T3 DK1947172 T3 DK 1947172T3
Authority
DK
Denmark
Prior art keywords
construction
metabolic control
metabolic
metabolite
metabolites
Prior art date
Application number
DK08000125.8T
Other languages
English (en)
Inventor
James C Liao
Original Assignee
Food Industry Res & Dev Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Food Industry Res & Dev Inst filed Critical Food Industry Res & Dev Inst
Application granted granted Critical
Publication of DK1947172T3 publication Critical patent/DK1947172T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Control Of Positive-Displacement Air Blowers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK08000125.8T 1999-07-27 2000-07-27 Konstruktion af metabolisk styring DK1947172T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14580199P 1999-07-27 1999-07-27
EP00950804A EP1220892B1 (en) 1999-07-27 2000-07-27 Engineering of metabolic control

Publications (1)

Publication Number Publication Date
DK1947172T3 true DK1947172T3 (da) 2013-03-25

Family

ID=22514617

Family Applications (4)

Application Number Title Priority Date Filing Date
DK10152563.2T DK2184366T3 (da) 1999-07-27 2000-07-27 Fremgangsmåde til fremstilling af lycopen
DK08000125.8T DK1947172T3 (da) 1999-07-27 2000-07-27 Konstruktion af metabolisk styring
DK00950804T DK1220892T3 (da) 1999-07-27 2000-07-27 Engineering af metabolisk kontrol
DK10152561.6T DK2182072T3 (da) 1999-07-27 2000-07-27 Fremgangsmåde til produktion af isoprenoider

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK10152563.2T DK2184366T3 (da) 1999-07-27 2000-07-27 Fremgangsmåde til fremstilling af lycopen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK00950804T DK1220892T3 (da) 1999-07-27 2000-07-27 Engineering af metabolisk kontrol
DK10152561.6T DK2182072T3 (da) 1999-07-27 2000-07-27 Fremgangsmåde til produktion af isoprenoider

Country Status (9)

Country Link
US (1) US7122341B1 (da)
EP (4) EP1220892B1 (da)
JP (2) JP4685308B2 (da)
CN (4) CN100432216C (da)
AT (1) ATE386103T1 (da)
DE (1) DE60038032T2 (da)
DK (4) DK2184366T3 (da)
HK (3) HK1119742A1 (da)
WO (1) WO2001007567A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200934872A (en) 2008-02-05 2009-08-16 Echem Hightech Co Ltd A strain of genetically reengineered escherichia coli for biosynthesis of high yield carotenoids after mutation screening
CN102482648B (zh) 2009-06-22 2014-12-10 科德克希思公司 酮还原酶介导的产生α氯代醇的立体选择性途径
US9080192B2 (en) 2010-02-10 2015-07-14 Codexis, Inc. Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
CN101979587B (zh) * 2010-10-14 2013-05-01 浙江大学 少动鞘氨醇单胞菌的八氢番茄红素脱氢酶基因及其应用
WO2012174271A2 (en) 2011-06-16 2012-12-20 The Regents Of The University Of California Synthetic gene clusters
WO2014071182A1 (en) 2012-11-01 2014-05-08 Massachusetts Institute Of Technology Directed evolution of synthetic gene cluster
CN103232986B (zh) * 2013-05-27 2014-06-18 青岛蔚蓝生物集团有限公司 一种异戊二烯生产方法
US10900060B2 (en) * 2014-06-13 2021-01-26 Deinove Method of producing terpenes or terpenoids
RU2769873C2 (ru) 2015-07-13 2022-04-07 Пивот Байо, Инк. Способы и композиции для улучшения признаков растений
CN108291219B (zh) 2015-10-05 2023-02-17 麻省理工学院 使用重构nif簇的氮固定
CA3049258A1 (en) 2017-01-12 2018-07-19 Pivot Bio, Inc. Methods and compositions for improving plant traits
CN111587287A (zh) 2017-10-25 2020-08-25 皮沃特生物股份有限公司 用于改良固氮的工程微生物的方法和组合物
WO2019113387A1 (en) 2017-12-07 2019-06-13 Zymergen Inc. Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation
CA3086490A1 (en) 2017-12-21 2019-06-27 Zymergen Inc. Nepetalactol oxidoreductases, nepetalactol synthases, and microbes capable of producing nepetalactone
CN108441510B (zh) * 2018-03-26 2020-12-22 武汉天问生物科技有限公司 转基因水稻grh和黑金米的培育及grh目的基因的检测方法
CN108624600B (zh) * 2018-05-22 2021-06-18 昆明理工大学 锌指转录因子基因RkMsn4的用途
US11963530B2 (en) 2018-06-27 2024-04-23 Pivot Bio, Inc. Agricultural compositions comprising remodeled nitrogen fixing microbes
KR102229379B1 (ko) * 2019-06-11 2021-03-19 주식회사 제노포커스 파이토플루엔 고생산성 재조합 미생물 및 이를 이용한 파이토플루엔의 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2950888B2 (ja) * 1989-04-21 1999-09-20 麒麟麦酒株式会社 カロチノイドの合成に有用なｄｎａ鎖
US5429939A (en) 1989-04-21 1995-07-04 Kirin Beer Kabushiki Kaisha DNA sequences useful for the synthesis of carotenoids
US5530189A (en) 1990-03-02 1996-06-25 Amoco Corporation Lycopene biosynthesis in genetically engineered hosts
EP0725137B2 (en) * 1994-08-23 2005-03-02 Kirin Beer Kabushiki Kaisha Keto group introducing enzyme, dna coding for the same, and process for producing ketocarotenoid
WO1996008567A1 (en) * 1994-09-16 1996-03-21 Texas A & M University System Microorganisms and methods for overproduction of dahp by cloned pps gene
US5830692A (en) * 1995-03-24 1998-11-03 Consortium Fur Elektrochemische Industrie Gmbh Expression system which can be regulated
US5744341A (en) 1996-03-29 1998-04-28 University Of Maryland College Park Genes of carotenoid biosynthesis and metabolism and a system for screening for such genes
ES2200110T3 (es) * 1996-12-02 2004-03-01 F. Hoffmann-La Roche Ag Produccion fermentativa de caroteniodes mejorada.
JPH10327865A (ja) * 1997-05-29 1998-12-15 Kirin Brewery Co Ltd カロテノイド配糖体およびその製造法
US20020045220A1 (en) * 1999-10-13 2002-04-18 Chaitan Khosla Biosynthesis of polyketide synthase substrates

Also Published As

Publication number Publication date
EP1947172A3 (en) 2008-10-15
CN100432216C (zh) 2008-11-12
CN1896246B (zh) 2013-01-16
JP4685308B2 (ja) 2011-05-18
HK1142368A1 (en) 2010-12-03
ATE386103T1 (de) 2008-03-15
EP1220892A1 (en) 2002-07-10
EP2182072A3 (en) 2010-06-09
DE60038032D1 (de) 2008-03-27
DE60038032T2 (de) 2009-02-05
CN1365386A (zh) 2002-08-21
EP2182072A2 (en) 2010-05-05
EP1947172B1 (en) 2012-12-19
EP2184366A3 (en) 2010-06-02
EP2182072B1 (en) 2012-12-26
CN1670189A (zh) 2005-09-21
CN1896246A (zh) 2007-01-17
DK1220892T3 (da) 2008-06-09
HK1119742A1 (en) 2009-03-13
JP2003508085A (ja) 2003-03-04
EP1220892A4 (en) 2004-04-14
EP1947172A2 (en) 2008-07-23
CN1900304A (zh) 2007-01-24
JP5419829B2 (ja) 2014-02-19
CN1224698C (zh) 2005-10-26
WO2001007567A1 (en) 2001-02-01
US7122341B1 (en) 2006-10-17
EP2184366B1 (en) 2014-03-12
HK1142367A1 (en) 2010-12-03
DK2182072T3 (da) 2013-04-02
EP2184366A2 (en) 2010-05-12
EP1220892B1 (en) 2008-02-13
JP2010284173A (ja) 2010-12-24
DK2184366T3 (da) 2014-06-02

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