DK1910398T3 - 17-alfa-substituerede derivater af estradiol med sårhelende virkning - Google Patents

17-alfa-substituerede derivater af estradiol med sårhelende virkning

Info

Publication number
DK1910398T3
DK1910398T3 DK06762874.3T DK06762874T DK1910398T3 DK 1910398 T3 DK1910398 T3 DK 1910398T3 DK 06762874 T DK06762874 T DK 06762874T DK 1910398 T3 DK1910398 T3 DK 1910398T3
Authority
DK
Denmark
Prior art keywords
estradiol
alpha
wound healing
substituted derivatives
healing effect
Prior art date
Application number
DK06762874.3T
Other languages
English (en)
Inventor
Roberta Joudioux
Bettolo Rinaldo Marini
Mario Brufani
Francesca Ceccacci
Paolo Maria Farina
Luigi Filocamo
Barbara Garofalo
Gillian Ashcroft
Adriana Maggi
Luisa Maria Migneco
Original Assignee
Prime Europ Therapeuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prime Europ Therapeuticals filed Critical Prime Europ Therapeuticals
Application granted granted Critical
Publication of DK1910398T3 publication Critical patent/DK1910398T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0085Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK06762874.3T 2005-08-02 2006-07-28 17-alfa-substituerede derivater af estradiol med sårhelende virkning DK1910398T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001516A ITMI20051516A1 (it) 2005-08-02 2005-08-02 Derivati 17 alfa-sostituti dell'estradiolo ad attivita' cicatrizzante
PCT/EP2006/007488 WO2007014711A1 (en) 2005-08-02 2006-07-28 17-alpha-substituted derivatives of estradiol with wound-healing activity

Publications (1)

Publication Number Publication Date
DK1910398T3 true DK1910398T3 (da) 2011-02-14

Family

ID=37564355

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06762874.3T DK1910398T3 (da) 2005-08-02 2006-07-28 17-alfa-substituerede derivater af estradiol med sårhelende virkning

Country Status (10)

Country Link
US (1) US8357675B2 (da)
EP (1) EP1910398B1 (da)
AT (1) ATE489398T1 (da)
DE (1) DE602006018471D1 (da)
DK (1) DK1910398T3 (da)
ES (1) ES2356668T3 (da)
IT (1) ITMI20051516A1 (da)
PL (1) PL1910398T3 (da)
PT (1) PT1910398E (da)
WO (1) WO2007014711A1 (da)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1806131A3 (en) 1996-07-22 2007-08-01 Renovo Limited Use of sex steroid function modulators to treat wounds and fibrotic disorders

Also Published As

Publication number Publication date
EP1910398A1 (en) 2008-04-16
EP1910398B1 (en) 2010-11-24
DE602006018471D1 (de) 2011-01-05
WO2007014711A1 (en) 2007-02-08
PL1910398T3 (pl) 2011-05-31
US8357675B2 (en) 2013-01-22
US20100035796A1 (en) 2010-02-11
ES2356668T3 (es) 2011-04-12
PT1910398E (pt) 2011-02-25
ITMI20051516A1 (it) 2007-02-03
ATE489398T1 (de) 2010-12-15

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