DE602006018471D1 - 17-alpha-substituierte derivate von östradiol mit wundheilender wirkung - Google Patents

17-alpha-substituierte derivate von östradiol mit wundheilender wirkung

Info

Publication number
DE602006018471D1
DE602006018471D1 DE602006018471T DE602006018471T DE602006018471D1 DE 602006018471 D1 DE602006018471 D1 DE 602006018471D1 DE 602006018471 T DE602006018471 T DE 602006018471T DE 602006018471 T DE602006018471 T DE 602006018471T DE 602006018471 D1 DE602006018471 D1 DE 602006018471D1
Authority
DE
Germany
Prior art keywords
ostradiol
alpha
wound healing
substituted derivatives
healing effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006018471T
Other languages
English (en)
Inventor
Gillian Ashcroft
Mario Brufani
Francesca Ceccacci
Paolo Maria Farina
Luigi Filocamo
Barbara Garofalo
Roberta Joudioux
Adriana Maggi
Bettolo Rinaldo Marini
Luisa Maria Migneco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Archimica SpA
Original Assignee
Prime European Therapeuticals SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prime European Therapeuticals SpA filed Critical Prime European Therapeuticals SpA
Publication of DE602006018471D1 publication Critical patent/DE602006018471D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0085Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006018471T 2005-08-02 2006-07-28 17-alpha-substituierte derivate von östradiol mit wundheilender wirkung Active DE602006018471D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001516A ITMI20051516A1 (it) 2005-08-02 2005-08-02 Derivati 17 alfa-sostituti dell'estradiolo ad attivita' cicatrizzante
PCT/EP2006/007488 WO2007014711A1 (en) 2005-08-02 2006-07-28 17-alpha-substituted derivatives of estradiol with wound-healing activity

Publications (1)

Publication Number Publication Date
DE602006018471D1 true DE602006018471D1 (de) 2011-01-05

Family

ID=37564355

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006018471T Active DE602006018471D1 (de) 2005-08-02 2006-07-28 17-alpha-substituierte derivate von östradiol mit wundheilender wirkung

Country Status (10)

Country Link
US (1) US8357675B2 (de)
EP (1) EP1910398B1 (de)
AT (1) ATE489398T1 (de)
DE (1) DE602006018471D1 (de)
DK (1) DK1910398T3 (de)
ES (1) ES2356668T3 (de)
IT (1) ITMI20051516A1 (de)
PL (1) PL1910398T3 (de)
PT (1) PT1910398E (de)
WO (1) WO2007014711A1 (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE279916T1 (de) * 1996-07-22 2004-11-15 Renovo Ltd Verwendung von substanzen, die die östrogen wirkung fördern, zur behandlung von wunden

Also Published As

Publication number Publication date
US8357675B2 (en) 2013-01-22
EP1910398A1 (de) 2008-04-16
ITMI20051516A1 (it) 2007-02-03
ATE489398T1 (de) 2010-12-15
PL1910398T3 (pl) 2011-05-31
WO2007014711A1 (en) 2007-02-08
EP1910398B1 (de) 2010-11-24
US20100035796A1 (en) 2010-02-11
ES2356668T3 (es) 2011-04-12
DK1910398T3 (da) 2011-02-14
PT1910398E (pt) 2011-02-25

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DE602006018471D1 (de) 17-alpha-substituierte derivate von östradiol mit wundheilender wirkung
PE20070555A1 (es) Uso de valerato de estradiol en combinacion con dienogest para la terapia oral de la hemorragia uterina disfuncional unida con una anticoncepcion oral